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Aliases : yfhM, b2520
Description : bacterial alpha2-macroglobulin colonization factor ECAM; anti-host protease defense factor; periplasmic inner membrane-anchored lipoprotein [Ensembl]. MG2 domain, A-macroglobulin TED domain, Alpha-2-macroglobulin family, Bacterial macroglobulin domain 6, Alpha-2-macroglobulin bait region domain, Bacterial Alpha-2-macroglobulin MG5 domain, Bacterial Alpha-2-macroglobulin MG1 domain, Bacterial alpha-2-macroglobulin MG3 domain, Bacterial Alpha-2-macroglobulin MG10 domain [Interproscan].
Gene families : OG_02_0003588 (OrthoFinder) Phylogenetic Tree(s): No tree available for this family
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: AAC75573 | |
| Cluster | HCCA: Cluster_28 |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0004866 | endopeptidase inhibitor activity | IEA | Interproscan |
| CC | GO:0005615 | extracellular space | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| BP | GO:0000160 | phosphorelay signal transduction system | IEP | Enrichment |
| MF | GO:0003908 | methylated-DNA-[protein]-cysteine S-methyltransferase activity | IEP | Enrichment |
| MF | GO:0005216 | ion channel activity | IEP | Enrichment |
| MF | GO:0005244 | voltage-gated ion channel activity | IEP | Enrichment |
| MF | GO:0005247 | voltage-gated chloride channel activity | IEP | Enrichment |
| MF | GO:0005253 | anion channel activity | IEP | Enrichment |
| MF | GO:0005254 | chloride channel activity | IEP | Enrichment |
| BP | GO:0006821 | chloride transport | IEP | Enrichment |
| MF | GO:0008172 | S-methyltransferase activity | IEP | Enrichment |
| MF | GO:0008308 | voltage-gated anion channel activity | IEP | Enrichment |
| MF | GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity | IEP | Enrichment |
| BP | GO:0009056 | catabolic process | IEP | Enrichment |
| BP | GO:0009166 | nucleotide catabolic process | IEP | Enrichment |
| MF | GO:0015075 | ion transmembrane transporter activity | IEP | Enrichment |
| MF | GO:0015103 | inorganic anion transmembrane transporter activity | IEP | Enrichment |
| BP | GO:0015698 | inorganic anion transport | IEP | Enrichment |
| MF | GO:0022832 | voltage-gated channel activity | IEP | Enrichment |
| MF | GO:0022836 | gated channel activity | IEP | Enrichment |
| BP | GO:0034404 | nucleobase-containing small molecule biosynthetic process | IEP | Enrichment |
| BP | GO:0034655 | nucleobase-containing compound catabolic process | IEP | Enrichment |
| BP | GO:0035556 | intracellular signal transduction | IEP | Enrichment |
| BP | GO:0044270 | cellular nitrogen compound catabolic process | IEP | Enrichment |
| BP | GO:0046434 | organophosphate catabolic process | IEP | Enrichment |
| BP | GO:0046700 | heterocycle catabolic process | IEP | Enrichment |
| BP | GO:0050789 | regulation of biological process | IEP | Enrichment |
| BP | GO:0050794 | regulation of cellular process | IEP | Enrichment |
| BP | GO:0065007 | biological regulation | IEP | Enrichment |
| BP | GO:1901292 | nucleoside phosphate catabolic process | IEP | Enrichment |
| BP | GO:1901575 | organic substance catabolic process | IEP | Enrichment |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR041203 | Bact_A2M_MG5 | 485 | 610 |
| IPR040639 | A2MG_MG1 | 59 | 163 |
| IPR041246 | Bact_MG10 | 1505 | 1638 |
| IPR011626 | Alpha-macroglobulin_TED | 1176 | 1285 |
| IPR011625 | A2M_N_BRD | 759 | 906 |
| IPR002890 | MG2 | 388 | 479 |
| IPR001599 | Macroglobln_a2 | 977 | 1056 |
| IPR041462 | Bact_A2M_MG6 | 616 | 741 |
| IPR021868 | Alpha_2_Macroglob_MG3 | 289 | 381 |
| UniProtKB | P76578 |