AAC76980 (purH, b4006)

Aliases : purH, b4006

Description : IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase [Ensembl]. MGS-like domain, AICARFT/IMPCHase bienzyme [Interproscan].

Gene families : OG_02_0000542 (OrthoFinder) Phylogenetic Tree(s): OG0000542_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC76980
Cluster	HCCA: Cluster_24

Target	Alias	Description	ECC score	Gene Family Method
AAK98855	spr0051, purH	Phosphoribosylaminoimidazolecarboxamide...	0.17	OrthoFinder
AAL23004	STM4176, purH	phosphoribosylaminoimidazolecarboxamide...	0.41	OrthoFinder
AEA94177	purH, OG1RF_11490	bifunctional purine biosynthesis protein PurH [Ensembl]....	0.21	OrthoFinder
AGT26493	N559_4909	phosphoribosylaminoimidazolecarboxamide...	0.35	OrthoFinder
AKI49759	purH, L2625_01901	phosphoribosylaminoimidazolecarboxamide...	0.13	OrthoFinder
CCG26113	No alias	IMP cyclohydrolase /...	0.16	OrthoFinder
CCL18088	purH, BN171_210024	Bifunctional purine biosynthesis protein purH (Includes:...	0.1	OrthoFinder
CCP43705	purH, Rv0957	Probable bifunctional purine biosynthesis protein PurH:...	0.02	OrthoFinder
CPC40781	purH, ERS093114_00351	IMP cyclohydrolase [Ensembl]. MGS-like domain,...	0.2	OrthoFinder
CRO51482	purH	Bifunctional purine biosynthesis protein PurH [Ensembl]....	0.03	OrthoFinder
EDJ91669	purH, CGSHi22421_07938	bifunctional phosphoribosylaminoimidazolecarboxamide...	0.1	OrthoFinder
KNA49649	VCV51_030205	phosphoribosylaminoimidazolecarboxamide...	0.2	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003937	IMP cyclohydrolase activity	IEA	Interproscan
MF	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006164	purine nucleotide biosynthetic process	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	None	Extended
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
MF	GO:0019238	cyclohydrolase activity	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:0072522	purine-containing compound biosynthetic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	IEP	Enrichment
MF	GO:0004019	adenylosuccinate synthase activity	IEP	Enrichment
MF	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004637	phosphoribosylamine-glycine ligase activity	IEP	Enrichment
MF	GO:0005215	transporter activity	IEP	Enrichment
BP	GO:0006144	purine nucleobase metabolic process	IEP	Enrichment
BP	GO:0006177	GMP biosynthetic process	IEP	Enrichment
BP	GO:0006188	IMP biosynthetic process	IEP	Enrichment
BP	GO:0006189	'de novo' IMP biosynthetic process	IEP	Enrichment
BP	GO:0009112	nucleobase metabolic process	IEP	Enrichment
BP	GO:0009113	purine nucleobase biosynthetic process	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009403	toxin biosynthetic process	IEP	Enrichment
BP	GO:0009404	toxin metabolic process	IEP	Enrichment
CC	GO:0016020	membrane	IEP	Enrichment
MF	GO:0016597	amino acid binding	IEP	Enrichment
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	IEP	Enrichment
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016743	carboxyl- or carbamoyltransferase activity	IEP	Enrichment
MF	GO:0016842	amidine-lyase activity	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
BP	GO:0019748	secondary metabolic process	IEP	Enrichment
MF	GO:0022857	transmembrane transporter activity	IEP	Enrichment
BP	GO:0042440	pigment metabolic process	IEP	Enrichment
BP	GO:0044550	secondary metabolite biosynthetic process	IEP	Enrichment
BP	GO:0046037	GMP metabolic process	IEP	Enrichment
BP	GO:0046040	IMP metabolic process	IEP	Enrichment
BP	GO:0046112	nucleobase biosynthetic process	IEP	Enrichment
BP	GO:0046148	pigment biosynthetic process	IEP	Enrichment
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Enrichment
BP	GO:0055085	transmembrane transport	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR011607	MGS-like_dom	19	132
IPR002695	PurH-like	137	460

External Links

UniProtKB	P15639

AAC76980 (purH, b4006)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation