AAC76980 (purH, b4006)


Aliases : purH, b4006

Description : IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase [Ensembl]. MGS-like domain, AICARFT/IMPCHase bienzyme [Interproscan].


Gene families : OG_02_0000542 (OrthoFinder) Phylogenetic Tree(s): OG0000542_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AAC76980
Cluster HCCA: Cluster_24

Target Alias Description ECC score Gene Family Method Actions
AAK98855 spr0051, purH Phosphoribosylaminoimidazolecarboxamide... 0.17 OrthoFinder
AAL23004 STM4176, purH phosphoribosylaminoimidazolecarboxamide... 0.41 OrthoFinder
AEA94177 purH, OG1RF_11490 bifunctional purine biosynthesis protein PurH [Ensembl].... 0.21 OrthoFinder
AGT26493 N559_4909 phosphoribosylaminoimidazolecarboxamide... 0.35 OrthoFinder
AKI49759 purH, L2625_01901 phosphoribosylaminoimidazolecarboxamide... 0.13 OrthoFinder
CCG26113 No alias IMP cyclohydrolase /... 0.16 OrthoFinder
CCL18088 purH, BN171_210024 Bifunctional purine biosynthesis protein purH (Includes:... 0.1 OrthoFinder
CCP43705 purH, Rv0957 Probable bifunctional purine biosynthesis protein PurH:... 0.02 OrthoFinder
CPC40781 purH, ERS093114_00351 IMP cyclohydrolase [Ensembl]. MGS-like domain,... 0.2 OrthoFinder
CRO51482 purH Bifunctional purine biosynthesis protein PurH [Ensembl].... 0.03 OrthoFinder
EDJ91669 purH, CGSHi22421_07938 bifunctional phosphoribosylaminoimidazolecarboxamide... 0.1 OrthoFinder
KNA49649 VCV51_030205 phosphoribosylaminoimidazolecarboxamide... 0.2 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003937 IMP cyclohydrolase activity IEA Interproscan
MF GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity IEA Interproscan
BP GO:0006164 purine nucleotide biosynthetic process IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Enrichment
MF GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity IEP Enrichment
MF GO:0004019 adenylosuccinate synthase activity IEP Enrichment
MF GO:0004486 methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity IEP Enrichment
MF GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IEP Enrichment
MF GO:0004637 phosphoribosylamine-glycine ligase activity IEP Enrichment
MF GO:0005215 transporter activity IEP Enrichment
BP GO:0006144 purine nucleobase metabolic process IEP Enrichment
BP GO:0006177 GMP biosynthetic process IEP Enrichment
BP GO:0006188 IMP biosynthetic process IEP Enrichment
BP GO:0006189 'de novo' IMP biosynthetic process IEP Enrichment
BP GO:0009112 nucleobase metabolic process IEP Enrichment
BP GO:0009113 purine nucleobase biosynthetic process IEP Enrichment
BP GO:0009123 nucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009124 nucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009126 purine nucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009127 purine nucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009150 purine ribonucleotide metabolic process IEP Enrichment
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Enrichment
BP GO:0009156 ribonucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009161 ribonucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009167 purine ribonucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009259 ribonucleotide metabolic process IEP Enrichment
BP GO:0009260 ribonucleotide biosynthetic process IEP Enrichment
BP GO:0009403 toxin biosynthetic process IEP Enrichment
BP GO:0009404 toxin metabolic process IEP Enrichment
CC GO:0016020 membrane IEP Enrichment
MF GO:0016597 amino acid binding IEP Enrichment
MF GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors IEP Enrichment
MF GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor IEP Enrichment
MF GO:0016743 carboxyl- or carbamoyltransferase activity IEP Enrichment
MF GO:0016842 amidine-lyase activity IEP Enrichment
MF GO:0016874 ligase activity IEP Enrichment
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Enrichment
MF GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor IEP Enrichment
BP GO:0019693 ribose phosphate metabolic process IEP Enrichment
BP GO:0019748 secondary metabolic process IEP Enrichment
MF GO:0022857 transmembrane transporter activity IEP Enrichment
BP GO:0042440 pigment metabolic process IEP Enrichment
BP GO:0044550 secondary metabolite biosynthetic process IEP Enrichment
BP GO:0046037 GMP metabolic process IEP Enrichment
BP GO:0046040 IMP metabolic process IEP Enrichment
BP GO:0046112 nucleobase biosynthetic process IEP Enrichment
BP GO:0046148 pigment biosynthetic process IEP Enrichment
BP GO:0046390 ribose phosphate biosynthetic process IEP Enrichment
BP GO:0055085 transmembrane transport IEP Enrichment
BP GO:1901135 carbohydrate derivative metabolic process IEP Enrichment
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR011607 MGS-like_dom 19 132
IPR002695 PurH-like 137 460
UniProtKB P15639