AAC77028 (uvrA, b4058)

Aliases : uvrA, b4058

Description : ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC [Ensembl]. ABC transporter, UvrA interaction domain, UvrA DNA-binding domain [Interproscan].

Gene families : OG_02_0000216 (OrthoFinder) Phylogenetic Tree(s): OG0000216_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC77028
Cluster	HCCA: Cluster_41

Target	Alias	Description	ECC score	Gene Family Method
AAK98975	spr0171, uvrA	Excinuclease ABC-subunit A [Ensembl]. ABC transporter,...	0.03	OrthoFinder
AAL23078	STM4254, uvrA	DNA excision repair enzyme [Ensembl]. ABC transporter,...	0.08	OrthoFinder
AGT26437	N559_4853	excinuclease ABC subunit A [Ensembl]. UvrA DNA-binding...	0.09	OrthoFinder
CCG26819	No alias	Excinuclease ABC subunit A [Ensembl]. ABC transporter,...	0.03	OrthoFinder
CCP44402	uvrA, Rv1638	Probable excinuclease ABC (subunit A-DNA-binding ATPase)...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
MF	GO:0016887	ATPase	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0002097	tRNA wobble base modification	IEP	Enrichment
BP	GO:0002098	tRNA wobble uridine modification	IEP	Enrichment
BP	GO:0002143	tRNA wobble position uridine thiolation	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003677	DNA binding	IEP	Enrichment
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	IEP	Enrichment
MF	GO:0004655	porphobilinogen synthase activity	IEP	Enrichment
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Enrichment
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006188	IMP biosynthetic process	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006282	regulation of DNA repair	IEP	Enrichment
BP	GO:0006353	DNA-templated transcription, termination	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
BP	GO:0008152	metabolic process	IEP	Enrichment
MF	GO:0008907	integrase activity	IEP	Enrichment
BP	GO:0009116	nucleoside metabolic process	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009165	nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009432	SOS response	IEP	Enrichment
BP	GO:0016032	viral process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Enrichment
MF	GO:0016778	diphosphotransferase activity	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0019076	viral release from host cell	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
BP	GO:0032774	RNA biosynthetic process	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0034227	tRNA thio-modification	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0035890	exit from host	IEP	Enrichment
BP	GO:0035891	exit from host cell	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0044237	cellular metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0044403	biological process involved in symbiotic interaction	IEP	Enrichment
BP	GO:0046040	IMP metabolic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0048583	regulation of response to stimulus	IEP	Enrichment
BP	GO:0051052	regulation of DNA metabolic process	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
BP	GO:0051302	regulation of cell division	IEP	Enrichment
BP	GO:0051701	biological process involved in interaction with host	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
BP	GO:0051782	negative regulation of cell division	IEP	Enrichment
BP	GO:0052126	movement in host environment	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0071704	organic substance metabolic process	IEP	Enrichment
BP	GO:0080134	regulation of response to stress	IEP	Enrichment
BP	GO:0080135	regulation of cellular response to stress	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901657	glycosyl compound metabolic process	IEP	Enrichment
BP	GO:2001020	regulation of response to DNA damage stimulus	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR041102	UvrA_inter	130	237
IPR041552	UvrA_DNA-bd	290	399
IPR003439	ABC_transporter-like_ATP-bd	806	860

External Links

UniProtKB	P0A698

AAC77028 (uvrA, b4058)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation