AAC77302 (mcrB, b4346)

Aliases : mcrB, b4346

Description : 5-methylcytosine-specific restriction enzyme McrBC, subunit McrB [Ensembl]. Domain of unknown function (DUF3578), AAA domain (dynein-related subfamily) [Interproscan].

Gene families : OG_02_0001460 (OrthoFinder) Phylogenetic Tree(s): OG0001460_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC77302
Cluster	HCCA: Cluster_19

Target	Alias	Description	ECC score	Gene Family Method	Actions
AAL21640	STM2754	putative hexulose 6 phosphate synthase [Ensembl]. Domain...	0.06	OrthoFinder
CCL18450	BN171_2350002	Putative restriction enzyme [Ensembl]. AAA domain...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
MF	GO:0016887	ATPase	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003677	DNA binding	IEP	Enrichment
MF	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	IEP	Enrichment
MF	GO:0004655	porphobilinogen synthase activity	IEP	Enrichment
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Enrichment
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006188	IMP biosynthetic process	IEP	Enrichment
BP	GO:0006282	regulation of DNA repair	IEP	Enrichment
BP	GO:0006353	DNA-templated transcription, termination	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Enrichment
MF	GO:0008378	galactosyltransferase activity	IEP	Enrichment
MF	GO:0008907	integrase activity	IEP	Enrichment
MF	GO:0008918	lipopolysaccharide 3-alpha-galactosyltransferase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009165	nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Enrichment
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016778	diphosphotransferase activity	IEP	Enrichment
MF	GO:0016842	amidine-lyase activity	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0035250	UDP-galactosyltransferase activity	IEP	Enrichment
MF	GO:0043565	sequence-specific DNA binding	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0046040	IMP metabolic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0048583	regulation of response to stimulus	IEP	Enrichment
BP	GO:0051052	regulation of DNA metabolic process	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Enrichment
BP	GO:0080134	regulation of response to stress	IEP	Enrichment
BP	GO:0080135	regulation of cellular response to stress	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:2001020	regulation of response to DNA damage stimulus	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR011704	ATPase_dyneun-rel_AAA	196	350
IPR021961	DUF3578	11	98

External Links

UniProtKB	P15005

AAC77302 (mcrB, b4346)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation