CBI66850 (miaB, HPB8_1293)


Aliases : miaB, HPB8_1293

Description : bifunctional enzyme involved in thiolation and methylation of tRNA [Ensembl]. Radical SAM superfamily, Uncharacterized protein family UPF0004 [Interproscan].


Gene families : OG_02_0000795 (OrthoFinder) Phylogenetic Tree(s): OG0000795_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: CBI66850
Cluster HCCA: Cluster_2

Target Alias Description ECC score Gene Family Method Actions
AAC73762 miaB, b0661 tRNA-i(6)A37 methylthiotransferase [Ensembl]. TRAM... 0.05 OrthoFinder
AAL19621 STM0670, miaB methylthiolation of isopentenylated A37 derivatives in... 0.05 OrthoFinder
AGT25277 N559_3635, MiaB tRNA-I(6)A37 thiotransferase enzyme MiaB [Ensembl]. TRAM... 0.03 OrthoFinder
CCP45531 Rv2733c Conserved hypothetical alanine, arginine-rich protein... 0.03 OrthoFinder
CPC82262 miaB_2, ERS093114_01406 MiaB family protein%2C possibly involved in tRNA or rRNA... 0.02 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0035596 methylthiotransferase activity IEA Interproscan
MF GO:0051536 iron-sulfur cluster binding IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Enrichment
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEP Enrichment
MF GO:0003883 CTP synthase activity IEP Enrichment
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Enrichment
MF GO:0003924 GTPase activity IEP Enrichment
MF GO:0004129 cytochrome-c oxidase activity IEP Enrichment
MF GO:0004150 dihydroneopterin aldolase activity IEP Enrichment
MF GO:0004175 endopeptidase activity IEP Enrichment
MF GO:0004298 threonine-type endopeptidase activity IEP Enrichment
MF GO:0004497 monooxygenase activity IEP Enrichment
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Enrichment
MF GO:0004832 valine-tRNA ligase activity IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
MF GO:0005525 GTP binding IEP Enrichment
CC GO:0005694 chromosome IEP Enrichment
CC GO:0005839 proteasome core complex IEP Enrichment
BP GO:0006418 tRNA aminoacylation for protein translation IEP Enrichment
BP GO:0006438 valyl-tRNA aminoacylation IEP Enrichment
BP GO:0006457 protein folding IEP Enrichment
BP GO:0006520 cellular amino acid metabolic process IEP Enrichment
MF GO:0008320 protein transmembrane transporter activity IEP Enrichment
BP GO:0009060 aerobic respiration IEP Enrichment
MF GO:0015399 primary active transmembrane transporter activity IEP Enrichment
MF GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity IEP Enrichment
BP GO:0015980 energy derivation by oxidation of organic compounds IEP Enrichment
MF GO:0016597 amino acid binding IEP Enrichment
MF GO:0016675 oxidoreductase activity, acting on a heme group of donors IEP Enrichment
MF GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen IEP Enrichment
MF GO:0016703 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) IEP Enrichment
MF GO:0016743 carboxyl- or carbamoyltransferase activity IEP Enrichment
MF GO:0016832 aldehyde-lyase activity IEP Enrichment
MF GO:0016859 cis-trans isomerase activity IEP Enrichment
MF GO:0016874 ligase activity IEP Enrichment
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Enrichment
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
MF GO:0017111 nucleoside-triphosphatase activity IEP Enrichment
MF GO:0018580 nitronate monooxygenase activity IEP Enrichment
MF GO:0019001 guanyl nucleotide binding IEP Enrichment
MF GO:0020037 heme binding IEP Enrichment
MF GO:0022884 macromolecule transmembrane transporter activity IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
MF GO:0032561 guanyl ribonucleotide binding IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
BP GO:0043038 amino acid activation IEP Enrichment
BP GO:0043039 tRNA aminoacylation IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
BP GO:0045333 cellular respiration IEP Enrichment
MF GO:0046906 tetrapyrrole binding IEP Enrichment
MF GO:0070003 threonine-type peptidase activity IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:0140096 catalytic activity, acting on a protein IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
MF GO:0140318 protein transporter activity IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
InterPro domains Description Start Stop
IPR007197 rSAM 132 305
IPR013848 Methylthiotransferase_N 1 88
UniProtKB D7FF93