AKI49552 (hemD, L2625_01660)

Aliases : hemD, L2625_01660

Description : uroporphyrinogen-III synthase [Ensembl]. Tetrapyrrole biosynthesis [Interproscan].

Gene families : OG_02_0000411 (OrthoFinder) Phylogenetic Tree(s): OG0000411_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI49552
Cluster	HCCA: Cluster_24

Target	Alias	Description	ECC score	Gene Family Method
CCL19874	cbiF, BN171_3580009	Cobalt-precorrin-4 C(11)-methyltransferase...	0.04	OrthoFinder
CCP43248	hemD, Rv0511	Probable uroporphyrin-III C-methyltransferase HemD...	0.04	OrthoFinder
CPC85423	hemD, ERS093114_01491	uroporphyrinogen III synthase [Ensembl]....	0.05	OrthoFinder
CRP39831	cysG_2	Siroheme synthase [Ensembl]. Putative NAD(P)-binding,...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004852	uroporphyrinogen-III synthase activity	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016829	lyase activity	None	Extended
MF	GO:0016835	carbon-oxygen lyase activity	None	Extended
MF	GO:0016836	hydro-lyase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0033013	tetrapyrrole metabolic process	None	Extended
BP	GO:0033014	tetrapyrrole biosynthetic process	IEA	Interproscan
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
BP	GO:0000902	cell morphogenesis	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003678	DNA helicase activity	IEP	Enrichment
MF	GO:0003690	double-stranded DNA binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003896	DNA primase activity	IEP	Enrichment
MF	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004140	dephospho-CoA kinase activity	IEP	Enrichment
MF	GO:0004181	metallocarboxypeptidase activity	IEP	Enrichment
MF	GO:0004325	ferrochelatase activity	IEP	Enrichment
MF	GO:0004386	helicase activity	IEP	Enrichment
MF	GO:0004418	hydroxymethylbilane synthase activity	IEP	Enrichment
MF	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004527	exonuclease activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006298	mismatch repair	IEP	Enrichment
BP	GO:0006310	DNA recombination	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006528	asparagine metabolic process	IEP	Enrichment
BP	GO:0006529	asparagine biosynthetic process	IEP	Enrichment
BP	GO:0006720	isoprenoid metabolic process	IEP	Enrichment
BP	GO:0006778	porphyrin-containing compound metabolic process	IEP	Enrichment
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008235	metalloexopeptidase activity	IEP	Enrichment
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Enrichment
MF	GO:0008312	7S RNA binding	IEP	Enrichment
MF	GO:0008531	riboflavin kinase activity	IEP	Enrichment
BP	GO:0008616	queuosine biosynthetic process	IEP	Enrichment
MF	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	IEP	Enrichment
MF	GO:0008830	dTDP-4-dehydrorhamnose 3,5-epimerase activity	IEP	Enrichment
MF	GO:0008839	4-hydroxy-tetrahydrodipicolinate reductase	IEP	Enrichment
MF	GO:0008883	glutamyl-tRNA reductase activity	IEP	Enrichment
BP	GO:0009066	aspartate family amino acid metabolic process	IEP	Enrichment
BP	GO:0009067	aspartate family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009116	nucleoside metabolic process	IEP	Enrichment
BP	GO:0009119	ribonucleoside metabolic process	IEP	Enrichment
BP	GO:0009163	nucleoside biosynthetic process	IEP	Enrichment
MF	GO:0009378	four-way junction helicase activity	IEP	Enrichment
CC	GO:0009379	Holliday junction helicase complex	IEP	Enrichment
BP	GO:0009653	anatomical structure morphogenesis	IEP	Enrichment
BP	GO:0015937	coenzyme A biosynthetic process	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016744	transketolase or transaldolase activity	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0030983	mismatched DNA binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
CC	GO:0033202	DNA helicase complex	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	IEP	Enrichment
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0042455	ribonucleoside biosynthetic process	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Enrichment
BP	GO:0046116	queuosine metabolic process	IEP	Enrichment
CC	GO:0048500	signal recognition particle	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Enrichment
BP	GO:1901657	glycosyl compound metabolic process	IEP	Enrichment
BP	GO:1901659	glycosyl compound biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR003754	4pyrrol_synth_uPrphyn_synth	17	231

External Links

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AKI49552 (hemD, L2625_01660)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation