AKI49656 (leuS, L2625_01769)

Aliases : leuS, L2625_01769

Description : leucyl-tRNA synthetase [Ensembl]. Methionyl/Leucyl tRNA synthetase, Leucyl-tRNA synthetase, Aminoacyl-tRNA synthetase, Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase [Interproscan].

Gene families : OG_02_0000728 (OrthoFinder) Phylogenetic Tree(s): OG0000728_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI49656
Cluster	HCCA: Cluster_18

Target	Alias	Description	ECC score	Gene Family Method
AAC73743	leuS, b0642	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.11	OrthoFinder
AAK99039	spr0235, leuS	Leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.08	OrthoFinder
AAL19599	STM0648, leuS	leucine tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.07	OrthoFinder
AGT25290	N559_3648	leucyl-tRNA synthetase [Ensembl]. Domain 2,...	0.09	OrthoFinder
AHY40297	leuS, CJ8421_05425	leucyl-tRNA ligase [Ensembl]. Leucyl-tRNA synthetase,...	0.04	OrthoFinder
AKP15329	leuS, WX61_01280	Leucine--tRNA ligase [Ensembl]. Leucyl-tRNA synthetase,...	0.07	OrthoFinder
CBI67232	leuS, HPB8_1675	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.04	OrthoFinder
CCG26473	No alias	Leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.07	OrthoFinder
CRP36119	leuS	Leucine--tRNA ligase [Ensembl]. Leucyl-tRNA synthetase,...	0.08	OrthoFinder
EDJ91709	leuS, CGSHi22421_08138	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.04	OrthoFinder
KNA56394	VCV51_032954	leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA...	0.11	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0002161	aminoacyl-tRNA editing activity	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0052689	carboxylic ester hydrolase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003747	translation release factor activity	IEP	Enrichment
MF	GO:0003883	CTP synthase activity	IEP	Enrichment
MF	GO:0003896	DNA primase activity	IEP	Enrichment
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004347	glucose-6-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Enrichment
MF	GO:0004527	exonuclease activity	IEP	Enrichment
MF	GO:0004652	polynucleotide adenylyltransferase activity	IEP	Enrichment
MF	GO:0004664	prephenate dehydratase activity	IEP	Enrichment
MF	GO:0004788	thiamine diphosphokinase activity	IEP	Enrichment
MF	GO:0004810	tRNA adenylyltransferase activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006396	RNA processing	IEP	Enrichment
BP	GO:0006415	translational termination	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006450	regulation of translational fidelity	IEP	Enrichment
BP	GO:0006528	asparagine metabolic process	IEP	Enrichment
BP	GO:0006529	asparagine biosynthetic process	IEP	Enrichment
BP	GO:0006558	L-phenylalanine metabolic process	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
MF	GO:0008079	translation termination factor activity	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008135	translation factor activity, RNA binding	IEP	Enrichment
MF	GO:0008144	drug binding	IEP	Enrichment
MF	GO:0008408	3'-5' exonuclease activity	IEP	Enrichment
BP	GO:0008616	queuosine biosynthetic process	IEP	Enrichment
MF	GO:0008658	penicillin binding	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0009094	L-phenylalanine biosynthetic process	IEP	Enrichment
BP	GO:0009119	ribonucleoside metabolic process	IEP	Enrichment
BP	GO:0009163	nucleoside biosynthetic process	IEP	Enrichment
BP	GO:0009229	thiamine diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
BP	GO:0017013	protein flavinylation	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0022411	cellular component disassembly	IEP	Enrichment
MF	GO:0030975	thiamine binding	IEP	Enrichment
MF	GO:0031406	carboxylic acid binding	IEP	Enrichment
BP	GO:0031554	regulation of DNA-templated transcription, termination	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Enrichment
BP	GO:0032984	protein-containing complex disassembly	IEP	Enrichment
MF	GO:0033218	amide binding	IEP	Enrichment
MF	GO:0033293	monocarboxylic acid binding	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0042357	thiamine diphosphate metabolic process	IEP	Enrichment
BP	GO:0042455	ribonucleoside biosynthetic process	IEP	Enrichment
MF	GO:0043177	organic acid binding	IEP	Enrichment
BP	GO:0043244	regulation of protein-containing complex disassembly	IEP	Enrichment
BP	GO:0043624	cellular protein complex disassembly	IEP	Enrichment
BP	GO:0043933	protein-containing complex subunit organization	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
MF	GO:0045182	translation regulator activity	IEP	Enrichment
BP	GO:0046116	queuosine metabolic process	IEP	Enrichment
BP	GO:0046168	glycerol-3-phosphate catabolic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
MF	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
BP	GO:0051128	regulation of cellular component organization	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
BP	GO:0052646	alditol phosphate metabolic process	IEP	Enrichment
BP	GO:0065008	regulation of biological quality	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0090079	translation regulator activity, nucleic acid binding	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901659	glycosyl compound biosynthetic process	IEP	Enrichment
MF	GO:1901681	sulfur compound binding	IEP	Enrichment
BP	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	IEP	Enrichment
BP	GO:1902223	erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process	IEP	Enrichment
MF	GO:1990817	RNA adenylyltransferase activity	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR015413	Methionyl/Leucyl_tRNA_Synth	42	173
IPR025709	Leu_tRNA-synth_edit	222	402
IPR002300	aa-tRNA-synth_Ia	415	605
IPR013155	M/V/L/I-tRNA-synth_anticd-bd	657	766

External Links

No external refs found!

AKI49656 (leuS, L2625_01769)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation