AKP16109 (leuA, WX61_02083)

Aliases : leuA, WX61_02083

Description : 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA allosteric (dimerisation) domain [Interproscan].

Gene families : OG_02_0000655 (OrthoFinder) Phylogenetic Tree(s): OG0000655_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKP16109
Cluster	HCCA: Cluster_12

Target	Alias	Description	ECC score	Gene Family Method	Actions
CRP61562	leuA_2	2-isopropylmalate synthase [Ensembl]. HMGL-like [Interproscan].	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0003852	2-isopropylmalate synthase activity	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006551	leucine metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009098	leucine biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016746	acyltransferase activity	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
MF	GO:0046912	acyltransferase, acyl groups converted into alkyl on transfer	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004358	glutamate N-acetyltransferase activity	IEP	Enrichment
MF	GO:0004375	glycine dehydrogenase (decarboxylating) activity	IEP	Enrichment
MF	GO:0004611	phosphoenolpyruvate carboxykinase activity	IEP	Enrichment
MF	GO:0004743	pyruvate kinase activity	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
BP	GO:0005975	carbohydrate metabolic process	IEP	Enrichment
BP	GO:0006026	aminoglycan catabolic process	IEP	Enrichment
BP	GO:0006027	glycosaminoglycan catabolic process	IEP	Enrichment
BP	GO:0006525	arginine metabolic process	IEP	Enrichment
BP	GO:0006526	arginine biosynthetic process	IEP	Enrichment
BP	GO:0006544	glycine metabolic process	IEP	Enrichment
BP	GO:0006546	glycine catabolic process	IEP	Enrichment
MF	GO:0008080	N-acetyltransferase activity	IEP	Enrichment
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Enrichment
MF	GO:0008703	5-amino-6-(5-phosphoribosylamino)uracil reductase activity	IEP	Enrichment
MF	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	IEP	Enrichment
MF	GO:0008915	lipid-A-disaccharide synthase activity	IEP	Enrichment
MF	GO:0008964	phosphoenolpyruvate carboxylase activity	IEP	Enrichment
BP	GO:0009056	catabolic process	IEP	Enrichment
BP	GO:0009063	cellular amino acid catabolic process	IEP	Enrichment
BP	GO:0009071	serine family amino acid catabolic process	IEP	Enrichment
BP	GO:0009253	peptidoglycan catabolic process	IEP	Enrichment
BP	GO:0015977	carbon fixation	IEP	Enrichment
BP	GO:0016054	organic acid catabolic process	IEP	Enrichment
MF	GO:0016407	acetyltransferase activity	IEP	Enrichment
MF	GO:0016410	N-acyltransferase activity	IEP	Enrichment
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Enrichment
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Enrichment
MF	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	IEP	Enrichment
MF	GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	IEP	Enrichment
MF	GO:0016758	hexosyltransferase activity	IEP	Enrichment
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Enrichment
MF	GO:0030955	potassium ion binding	IEP	Enrichment
MF	GO:0031420	alkali metal ion binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0046395	carboxylic acid catabolic process	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
MF	GO:0061783	peptidoglycan muralytic activity	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Enrichment
BP	GO:1901575	organic substance catabolic process	IEP	Enrichment
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Enrichment
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013709	2-isopropylmalate_synth_dimer	452	582
IPR000891	PYR_CT	86	355

External Links

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AKP16109 (leuA, WX61_02083)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation