AAL22809 (STM3965, metE)

Aliases : STM3965, metE

Description : 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase [Ensembl]. Cobalamin-independent synthase [Interproscan].

Gene families : OG_02_0000815 (OrthoFinder) Phylogenetic Tree(s): OG0000815_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAL22809
Cluster	HCCA: Cluster_39

Target	Alias	Description	ECC score	Gene Family Method
AAC76832	metE, b3829	5-methyltetrahydropteroyltriglutamate-homocysteine...	0.34	OrthoFinder
AAK99318	spr0514, metE	Tetrahydropteroyltriglutamate methyltransferase...	0.03	OrthoFinder
AGT23847	N559_2131	5-methyltetrahydropteroyltriglutamate-homocysteine...	0.11	OrthoFinder
AHY40405	CJ8421_05990	5-methyltetrahydropteroyltriglutamate--homocysteine...	0.04	OrthoFinder
AKI49677	metE, L2625_01792	5-methyltetrahydropteroyltriglutamate-homocysteine...	0.05	OrthoFinder
AKP16035	metE, WX61_02008	5-methyltetrahydropteroyltriglutamate--homocysteine...	0.06	OrthoFinder
CPC90093	metE, ERS093114_01572	5-methyltetrahydropteroyltriglutamate--homocysteine...	0.04	OrthoFinder
EDJ90316	CGSHi22421_02271	5-methyltetrahydropteroyltriglutamate--homocysteine...	0.04	OrthoFinder
KNA58565	VCV51_031138	5-methyltetrahydropteroyltriglutamate-homocysteine...	0.14	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	None	Extended
BP	GO:0000097	sulfur amino acid biosynthetic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003871	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006555	methionine metabolic process	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	None	Extended
MF	GO:0008172	S-methyltransferase activity	None	Extended
MF	GO:0008270	zinc ion binding	IEA	Interproscan
BP	GO:0008652	cellular amino acid biosynthetic process	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009066	aspartate family amino acid metabolic process	None	Extended
BP	GO:0009067	aspartate family amino acid biosynthetic process	None	Extended
BP	GO:0009086	methionine biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0042085	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044272	sulfur compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended
BP	GO:1901607	alpha-amino acid biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0000287	magnesium ion binding	IEP	Enrichment
MF	GO:0004417	hydroxyethylthiazole kinase activity	IEP	Enrichment
MF	GO:0004478	methionine adenosyltransferase activity	IEP	Enrichment
MF	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity	IEP	Enrichment
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0006534	cysteine metabolic process	IEP	Enrichment
BP	GO:0006536	glutamate metabolic process	IEP	Enrichment
BP	GO:0006537	glutamate biosynthetic process	IEP	Enrichment
BP	GO:0006556	S-adenosylmethionine biosynthetic process	IEP	Enrichment
BP	GO:0006772	thiamine metabolic process	IEP	Enrichment
BP	GO:0006810	transport	IEP	Enrichment
MF	GO:0008705	methionine synthase activity	IEP	Enrichment
MF	GO:0009007	site-specific DNA-methyltransferase (adenine-specific) activity	IEP	Enrichment
MF	GO:0009008	DNA-methyltransferase activity	IEP	Enrichment
BP	GO:0009069	serine family amino acid metabolic process	IEP	Enrichment
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009092	homoserine metabolic process	IEP	Enrichment
BP	GO:0009228	thiamine biosynthetic process	IEP	Enrichment
BP	GO:0009403	toxin biosynthetic process	IEP	Enrichment
BP	GO:0009404	toxin metabolic process	IEP	Enrichment
BP	GO:0015833	peptide transport	IEP	Enrichment
MF	GO:0015930	glutamate synthase activity	IEP	Enrichment
CC	GO:0016020	membrane	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Enrichment
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Enrichment
MF	GO:0016778	diphosphotransferase activity	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
BP	GO:0019346	transsulfuration	IEP	Enrichment
BP	GO:0019748	secondary metabolic process	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0031419	cobalamin binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032775	DNA methylation on adenine	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
MF	GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	IEP	Enrichment
BP	GO:0042723	thiamine-containing compound metabolic process	IEP	Enrichment
BP	GO:0042724	thiamine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0042886	amide transport	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043650	dicarboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0044550	secondary metabolite biosynthetic process	IEP	Enrichment
BP	GO:0046500	S-adenosylmethionine metabolic process	IEP	Enrichment
MF	GO:0046906	tetrapyrrole binding	IEP	Enrichment
MF	GO:0050661	NADP binding	IEP	Enrichment
BP	GO:0050667	homocysteine metabolic process	IEP	Enrichment
BP	GO:0051179	localization	IEP	Enrichment
BP	GO:0051234	establishment of localization	IEP	Enrichment
BP	GO:0055085	transmembrane transport	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013215	Cbl-indep_Met_Synth_N	5	312
IPR002629	Met_Synth_C/arc	426	748

External Links

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AAL22809 (STM3965, metE)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation