CPD26981 (pykA, ERS093114_02430)

Aliases : pykA, ERS093114_02430

Description : Pyruvate kinase [Ensembl]. Pyruvate kinase, PEP-utilising enzyme [Interproscan].

Gene families : OG_02_0000218 (OrthoFinder) Phylogenetic Tree(s): OG0000218_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CPD26981
Cluster	HCCA: Cluster_10

Target	Alias	Description	ECC score	Gene Family Method
AAC74746	pykF, b1676	pyruvate kinase I [Ensembl]. Pyruvate kinase [Interproscan].	0.16	OrthoFinder
AAC74924	pykA, b1854	pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].	0.1	OrthoFinder
AAK99601	spr0797, pykF	Pyruvate kinase I; fructose-stimulated [Ensembl]....	0.12	OrthoFinder
AAL20302	STM1378, pykF	pyruvate kinase I [Ensembl]. Pyruvate kinase [Interproscan].	0.15	OrthoFinder
AAL20804	STM1888, pykA	pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].	0.06	OrthoFinder
AEA93466	pyk, OG1RF_10779	pyruvate kinase [Ensembl]. Pyruvate kinase,...	0.14	OrthoFinder
AGT23623	N559_1890	pyruvate kinase [Ensembl]. barrel domain, alpha/beta...	0.03	OrthoFinder
AGT23869	N559_2155	pyruvate kinase [Ensembl]. barrel domain, alpha/beta...	0.07	OrthoFinder
AKI49567	pyk, L2625_01676	pyruvate kinase [Ensembl]. PEP-utilising enzyme,...	0.04	OrthoFinder
AKP15076	pykA, WX61_01018	Pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].	0.05	OrthoFinder
CCG26415	No alias	Pyruvate kinase [Ensembl]. Pyruvate kinase [Interproscan].	0.05	OrthoFinder
KNA49521	VCV51_030321	pyruvate kinase [Ensembl]. Pyruvate kinase [Interproscan].	0.1	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004743	pyruvate kinase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0005975	carbohydrate metabolic process	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006090	pyruvate metabolic process	None	Extended
BP	GO:0006091	generation of precursor metabolites and energy	None	Extended
BP	GO:0006096	glycolytic process	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006165	nucleoside diphosphate phosphorylation	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006757	ATP generation from ADP	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009132	nucleoside diphosphate metabolic process	None	Extended
BP	GO:0009135	purine nucleoside diphosphate metabolic process	None	Extended
BP	GO:0009150	purine ribonucleotide metabolic process	None	Extended
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	None	Extended
BP	GO:0009185	ribonucleoside diphosphate metabolic process	None	Extended
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016052	carbohydrate catabolic process	None	Extended
BP	GO:0016310	phosphorylation	IEA	Interproscan
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEA	Interproscan
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030955	potassium ion binding	IEA	Interproscan
MF	GO:0031420	alkali metal ion binding	None	Extended
BP	GO:0032787	monocarboxylic acid metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046031	ADP metabolic process	None	Extended
BP	GO:0046034	ATP metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
BP	GO:0046939	nucleotide phosphorylation	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0003684	damaged DNA binding	IEP	Enrichment
MF	GO:0003872	6-phosphofructokinase activity	IEP	Enrichment
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEP	Enrichment
MF	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004332	fructose-bisphosphate aldolase activity	IEP	Enrichment
MF	GO:0004347	glucose-6-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Enrichment
MF	GO:0004618	phosphoglycerate kinase activity	IEP	Enrichment
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Enrichment
MF	GO:0004807	triose-phosphate isomerase activity	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0005996	monosaccharide metabolic process	IEP	Enrichment
BP	GO:0006006	glucose metabolic process	IEP	Enrichment
BP	GO:0006007	glucose catabolic process	IEP	Enrichment
BP	GO:0006098	pentose-phosphate shunt	IEP	Enrichment
BP	GO:0006177	GMP biosynthetic process	IEP	Enrichment
BP	GO:0006289	nucleotide-excision repair	IEP	Enrichment
BP	GO:0006739	NADP metabolic process	IEP	Enrichment
BP	GO:0006740	NADPH regeneration	IEP	Enrichment
MF	GO:0008175	tRNA methyltransferase activity	IEP	Enrichment
MF	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	IEP	Enrichment
MF	GO:0008270	zinc ion binding	IEP	Enrichment
MF	GO:0008443	phosphofructokinase activity	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
MF	GO:0015129	lactate transmembrane transporter activity	IEP	Enrichment
BP	GO:0015727	lactate transport	IEP	Enrichment
BP	GO:0015850	organic hydroxy compound transport	IEP	Enrichment
MF	GO:0016301	kinase activity	IEP	Enrichment
MF	GO:0016423	tRNA (guanine) methyltransferase activity	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016774	phosphotransferase activity, carboxyl group as acceptor	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016830	carbon-carbon lyase activity	IEP	Enrichment
MF	GO:0016832	aldehyde-lyase activity	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Enrichment
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Enrichment
MF	GO:0019200	carbohydrate kinase activity	IEP	Enrichment
BP	GO:0019318	hexose metabolic process	IEP	Enrichment
BP	GO:0019320	hexose catabolic process	IEP	Enrichment
MF	GO:0030145	manganese ion binding	IEP	Enrichment
MF	GO:0030246	carbohydrate binding	IEP	Enrichment
BP	GO:0045149	acetoin metabolic process	IEP	Enrichment
BP	GO:0045151	acetoin biosynthetic process	IEP	Enrichment
BP	GO:0046037	GMP metabolic process	IEP	Enrichment
BP	GO:0046165	alcohol biosynthetic process	IEP	Enrichment
BP	GO:0046365	monosaccharide catabolic process	IEP	Enrichment
MF	GO:0046914	transition metal ion binding	IEP	Enrichment
MF	GO:0047605	acetolactate decarboxylase activity	IEP	Enrichment
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Enrichment
MF	GO:1901618	organic hydroxy compound transmembrane transporter activity	IEP	Enrichment
BP	GO:1902652	secondary alcohol metabolic process	IEP	Enrichment
BP	GO:1902653	secondary alcohol biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR008279	PEP-util_enz_mobile_dom	507	575
IPR015795	Pyrv_Knase_C	358	470
IPR015793	Pyrv_Knase_brl	1	341

External Links

No external refs found!

CPD26981 (pykA, ERS093114_02430)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation