CRO36716 (metH)

Aliases : metH

Description : Methionine synthase [Ensembl]. B12 binding domain, Pterin binding enzyme, Homocysteine S-methyltransferase, Vitamin B12 dependent methionine synthase [Interproscan].

Gene families : OG_02_0000961 (OrthoFinder) Phylogenetic Tree(s): OG0000961_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: CRO36716
Cluster HCCA: Cluster_12

Target Alias Description ECC score Gene Family Method Actions
AAC73364 mmuM, b0261 CP4-6 prophage; S-methylmethionine:homocysteine... 0.09 OrthoFinder
AAL23012 STM4188, metH B12-dependent homocysteine-N5-methyltetrahydrofolate... 0.03 OrthoFinder
AKI49674 L2625_01789 bifunctional homocysteine S-methyltransferase... 0.03 OrthoFinder
CPC90060 metH, ERS093114_01571 5%2C10-methylenetetrahydrofolate reductase-like... 0.06 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0008705 methionine synthase activity IEA Interproscan
BP GO:0009086 methionine biosynthetic process IEA Interproscan
MF GO:0031419 cobalamin binding IEA Interproscan
BP GO:0042558 pteridine-containing compound metabolic process IEA Interproscan
MF GO:0046872 metal ion binding IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Enrichment
MF GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity IEP Enrichment
MF GO:0008270 zinc ion binding IEP Enrichment
MF GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors IEP Enrichment
MF GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor IEP Enrichment
BP GO:0017004 cytochrome complex assembly IEP Enrichment
BP GO:0022607 cellular component assembly IEP Enrichment
BP GO:0034622 cellular protein-containing complex assembly IEP Enrichment
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Enrichment
BP GO:0043933 protein-containing complex subunit organization IEP Enrichment
BP GO:0065003 protein-containing complex assembly IEP Enrichment
InterPro domains Description Start Stop
IPR003726 HCY_dom 24 332
IPR000489 Pterin-binding_dom 367 605
IPR003759 Cbl-bd_cap 664 737
IPR004223 VitB12-dep_Met_synth_activ_dom 946 1216
IPR006158 Cobalamin-bd 754 847