AAC73227 (lpd, b0116)


Aliases : lpd, b0116

Description : dihydrolipoyl dehydrogenase; E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes; glycine cleavage system L protein; dihydrolipoamide dehydrogenase [Ensembl]. Pyridine nucleotide-disulphide oxidoreductase [Interproscan].


Gene families : OG_02_0000040 (OrthoFinder) Phylogenetic Tree(s): OG0000040_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AAC73227
Cluster HCCA: Cluster_1

Target Alias Description ECC score Gene Family Method Actions
AAK99852 spr1048, acoL Dihydrolipoamide dehydrogenase [Ensembl].... 0.07 OrthoFinder
AAL19118 STM0154, lpdA lipoamide dehydrogenase (NADH) [Ensembl]. Pyridine... 0.25 OrthoFinder
AAL22964 STM4126, udhA soluble pyridine nucleotide transhydrogenase [Ensembl].... 0.09 OrthoFinder
ADK87170 lpdA, MPNE_0452 dihydrolipoyl dehydrogenase [Ensembl]. Pyridine... 0.04 OrthoFinder
AGT25922 N559_4307 dihydrolipoamide dehydrogenase [Ensembl]. dimerisation... 0.16 OrthoFinder
AKP14226 lpdA, WX61_00137 Dihydrolipoyl dehydrogenase [Ensembl]. Biotin-requiring... 0.06 OrthoFinder
CCP45656 mtr, Rv2855 NADPH-dependent mycothiol reductase Mtr [Ensembl].... 0.05 OrthoFinder
CPC40095 pdhD, ERS093114_00328 Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase... 0.13 OrthoFinder
CRP29375 lpd Dihydrolipoyl dehydrogenase [Ensembl]. Pyridine... 0.11 OrthoFinder
EDJ90985 CGSHi22421_02646 dihydrolipoamide dehydrogenase [Ensembl]. Pyridine... 0.04 OrthoFinder
KNA53278 VCV51_031622 dihydrolipoyl dehydrogenase [Ensembl]. Pyridine... 0.11 OrthoFinder
KNA53638 VCV51_033312 pyridine nucleotide-disulfide oxidoreductase [Ensembl].... 0.06 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0016491 oxidoreductase activity IEA Interproscan
BP GO:0045454 cell redox homeostasis IEA Interproscan
BP GO:0055114 obsolete oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0003735 structural constituent of ribosome IEP Enrichment
MF GO:0003746 translation elongation factor activity IEP Enrichment
MF GO:0003954 NADH dehydrogenase activity IEP Enrichment
MF GO:0003955 NAD(P)H dehydrogenase (quinone) activity IEP Enrichment
MF GO:0003989 acetyl-CoA carboxylase activity IEP Enrichment
MF GO:0004129 cytochrome-c oxidase activity IEP Enrichment
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Enrichment
MF GO:0005198 structural molecule activity IEP Enrichment
MF GO:0005261 cation channel activity IEP Enrichment
CC GO:0005575 cellular_component IEP Enrichment
CC GO:0005840 ribosome IEP Enrichment
BP GO:0006091 generation of precursor metabolites and energy IEP Enrichment
BP GO:0006098 pentose-phosphate shunt IEP Enrichment
BP GO:0006099 tricarboxylic acid cycle IEP Enrichment
BP GO:0006163 purine nucleotide metabolic process IEP Enrichment
BP GO:0006164 purine nucleotide biosynthetic process IEP Enrichment
BP GO:0006412 translation IEP Enrichment
BP GO:0006518 peptide metabolic process IEP Enrichment
BP GO:0006633 fatty acid biosynthetic process IEP Enrichment
BP GO:0006739 NADP metabolic process IEP Enrichment
BP GO:0006740 NADPH regeneration IEP Enrichment
BP GO:0006753 nucleoside phosphate metabolic process IEP Enrichment
BP GO:0006754 ATP biosynthetic process IEP Enrichment
BP GO:0006793 phosphorus metabolic process IEP Enrichment
BP GO:0006796 phosphate-containing compound metabolic process IEP Enrichment
BP GO:0006811 ion transport IEP Enrichment
BP GO:0006812 cation transport IEP Enrichment
MF GO:0008137 NADH dehydrogenase (ubiquinone) activity IEP Enrichment
BP GO:0008152 metabolic process IEP Enrichment
MF GO:0008324 cation transmembrane transporter activity IEP Enrichment
MF GO:0008924 malate dehydrogenase (quinone) activity IEP Enrichment
MF GO:0009055 electron transfer activity IEP Enrichment
BP GO:0009058 biosynthetic process IEP Enrichment
BP GO:0009059 macromolecule biosynthetic process IEP Enrichment
BP GO:0009060 aerobic respiration IEP Enrichment
BP GO:0009117 nucleotide metabolic process IEP Enrichment
BP GO:0009141 nucleoside triphosphate metabolic process IEP Enrichment
BP GO:0009142 nucleoside triphosphate biosynthetic process IEP Enrichment
BP GO:0009144 purine nucleoside triphosphate metabolic process IEP Enrichment
BP GO:0009145 purine nucleoside triphosphate biosynthetic process IEP Enrichment
BP GO:0009150 purine ribonucleotide metabolic process IEP Enrichment
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Enrichment
BP GO:0009165 nucleotide biosynthetic process IEP Enrichment
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Enrichment
BP GO:0009201 ribonucleoside triphosphate biosynthetic process IEP Enrichment
BP GO:0009205 purine ribonucleoside triphosphate metabolic process IEP Enrichment
BP GO:0009206 purine ribonucleoside triphosphate biosynthetic process IEP Enrichment
BP GO:0009259 ribonucleotide metabolic process IEP Enrichment
BP GO:0009260 ribonucleotide biosynthetic process IEP Enrichment
CC GO:0009317 acetyl-CoA carboxylase complex IEP Enrichment
MF GO:0015002 obsolete heme-copper terminal oxidase activity IEP Enrichment
MF GO:0015075 ion transmembrane transporter activity IEP Enrichment
MF GO:0015078 proton transmembrane transporter activity IEP Enrichment
MF GO:0015252 proton channel activity IEP Enrichment
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Enrichment
BP GO:0015980 energy derivation by oxidation of organic compounds IEP Enrichment
BP GO:0015985 energy coupled proton transport, down electrochemical gradient IEP Enrichment
BP GO:0015986 ATP synthesis coupled proton transport IEP Enrichment
MF GO:0016421 CoA carboxylase activity IEP Enrichment
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Enrichment
MF GO:0016615 malate dehydrogenase activity IEP Enrichment
MF GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEP Enrichment
MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEP Enrichment
MF GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor IEP Enrichment
MF GO:0016675 oxidoreductase activity, acting on a heme group of donors IEP Enrichment
MF GO:0016885 ligase activity, forming carbon-carbon bonds IEP Enrichment
MF GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor IEP Enrichment
BP GO:0019438 aromatic compound biosynthetic process IEP Enrichment
BP GO:0019538 protein metabolic process IEP Enrichment
BP GO:0019637 organophosphate metabolic process IEP Enrichment
BP GO:0019693 ribose phosphate metabolic process IEP Enrichment
MF GO:0022890 inorganic cation transmembrane transporter activity IEP Enrichment
CC GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain IEP Enrichment
BP GO:0034220 ion transmembrane transport IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
BP GO:0034645 cellular macromolecule biosynthetic process IEP Enrichment
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Enrichment
BP GO:0043043 peptide biosynthetic process IEP Enrichment
CC GO:0043226 organelle IEP Enrichment
CC GO:0043228 non-membrane-bounded organelle IEP Enrichment
CC GO:0043229 intracellular organelle IEP Enrichment
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Enrichment
BP GO:0043603 cellular amide metabolic process IEP Enrichment
BP GO:0043604 amide biosynthetic process IEP Enrichment
BP GO:0044237 cellular metabolic process IEP Enrichment
BP GO:0044238 primary metabolic process IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044260 cellular macromolecule metabolic process IEP Enrichment
BP GO:0044267 cellular protein metabolic process IEP Enrichment
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Enrichment
CC GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) IEP Enrichment
BP GO:0045333 cellular respiration IEP Enrichment
BP GO:0046034 ATP metabolic process IEP Enrichment
BP GO:0046390 ribose phosphate biosynthetic process IEP Enrichment
MF GO:0046933 proton-transporting ATP synthase activity, rotational mechanism IEP Enrichment
MF GO:0050136 NADH dehydrogenase (quinone) activity IEP Enrichment
BP GO:0051156 glucose 6-phosphate metabolic process IEP Enrichment
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Enrichment
BP GO:0072521 purine-containing compound metabolic process IEP Enrichment
BP GO:0072522 purine-containing compound biosynthetic process IEP Enrichment
BP GO:0090407 organophosphate biosynthetic process IEP Enrichment
BP GO:0098655 cation transmembrane transport IEP Enrichment
BP GO:0098660 inorganic ion transmembrane transport IEP Enrichment
BP GO:0098662 inorganic cation transmembrane transport IEP Enrichment
CC GO:0110165 cellular anatomical entity IEP Enrichment
BP GO:1901135 carbohydrate derivative metabolic process IEP Enrichment
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Enrichment
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Enrichment
BP GO:1901564 organonitrogen compound metabolic process IEP Enrichment
BP GO:1901566 organonitrogen compound biosynthetic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
BP GO:1902600 proton transmembrane transport IEP Enrichment
InterPro domains Description Start Stop
IPR023753 FAD/NAD-binding_dom 8 328
IPR004099 Pyr_nucl-diS_OxRdtase_dimer 347 455
UniProtKB P0A9P0