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  5. AAC73762

AAC73762 (miaB, b0661)


Aliases : miaB, b0661

Description : tRNA-i(6)A37 methylthiotransferase [Ensembl]. TRAM domain, Radical SAM superfamily, Uncharacterized protein family UPF0004 [Interproscan].


Gene families : OG_02_0000795 (OrthoFinder) Phylogenetic Tree(s): OG0000795_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AAC73762
Cluster HCCA: Cluster_41

Target Alias Description ECC score Gene Family Method Actions
AAL19621 STM0670, miaB methylthiolation of isopentenylated A37 derivatives in... 0.17 OrthoFinder
AGT25277 N559_3635, MiaB tRNA-I(6)A37 thiotransferase enzyme MiaB [Ensembl]. TRAM... 0.16 OrthoFinder
AHY39711 CJ8421_02290 (dimethylallyl)adenosine tRNA methylthiotransferase... 0.03 OrthoFinder
AKP15355 miaB, WX61_01307 (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB... 0.05 OrthoFinder
CBI66834 HPB8_1277 conserved hypothetical protein [Ensembl]. Radical SAM... 0.05 OrthoFinder
CBI66850 miaB, HPB8_1293 bifunctional enzyme involved in thiolation and... 0.05 OrthoFinder
CCP45531 Rv2733c Conserved hypothetical alanine, arginine-rich protein... 0.03 OrthoFinder
CPC82262 miaB_2, ERS093114_01406 MiaB family protein%2C possibly involved in tRNA or rRNA... 0.11 OrthoFinder
CRP36330 miaB (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB... 0.09 OrthoFinder
EDJ91266 CGSHi22421_02069 lipoyl synthase [Ensembl]. TRAM domain, Radical SAM... 0.08 OrthoFinder
KNA56400 VCV51_030677, MiaB tRNA-I(6)A37 thiotransferase enzyme MiaB [Ensembl]. TRAM... 0.18 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0035596 methylthiotransferase activity IEA Interproscan
MF GO:0051536 iron-sulfur cluster binding IEA Interproscan
MF GO:0051539 4 iron, 4 sulfur cluster binding IEA Interproscan
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Enrichment
MF GO:0002161 aminoacyl-tRNA editing activity IEP Enrichment
MF GO:0003676 nucleic acid binding IEP Enrichment
MF GO:0003723 RNA binding IEP Enrichment
MF GO:0003896 DNA primase activity IEP Enrichment
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Enrichment
MF GO:0003924 GTPase activity IEP Enrichment
MF GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity IEP Enrichment
MF GO:0004312 fatty acid synthase activity IEP Enrichment
MF GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity IEP Enrichment
MF GO:0004486 methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity IEP Enrichment
MF GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IEP Enrichment
MF GO:0004520 endodeoxyribonuclease activity IEP Enrichment
MF GO:0004652 polynucleotide adenylyltransferase activity IEP Enrichment
MF GO:0004749 ribose phosphate diphosphokinase activity IEP Enrichment
MF GO:0004810 tRNA adenylyltransferase activity IEP Enrichment
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Enrichment
MF GO:0004814 arginine-tRNA ligase activity IEP Enrichment
MF GO:0004817 cysteine-tRNA ligase activity IEP Enrichment
MF GO:0004832 valine-tRNA ligase activity IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
MF GO:0005525 GTP binding IEP Enrichment
CC GO:0005737 cytoplasm IEP Enrichment
BP GO:0006082 organic acid metabolic process IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006188 IMP biosynthetic process IEP Enrichment
BP GO:0006269 DNA replication, synthesis of RNA primer IEP Enrichment
BP GO:0006364 rRNA processing IEP Enrichment
BP GO:0006396 RNA processing IEP Enrichment
BP GO:0006399 tRNA metabolic process IEP Enrichment
BP GO:0006418 tRNA aminoacylation for protein translation IEP Enrichment
BP GO:0006420 arginyl-tRNA aminoacylation IEP Enrichment
BP GO:0006423 cysteinyl-tRNA aminoacylation IEP Enrichment
BP GO:0006438 valyl-tRNA aminoacylation IEP Enrichment
BP GO:0006520 cellular amino acid metabolic process IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0008152 metabolic process IEP Enrichment
MF GO:0008168 methyltransferase activity IEP Enrichment
MF GO:0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity IEP Enrichment
BP GO:0009116 nucleoside metabolic process IEP Enrichment
BP GO:0009165 nucleotide biosynthetic process IEP Enrichment
BP GO:0009987 cellular process IEP Enrichment
BP GO:0016070 RNA metabolic process IEP Enrichment
BP GO:0016072 rRNA metabolic process IEP Enrichment
MF GO:0016462 pyrophosphatase activity IEP Enrichment
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Enrichment
MF GO:0016778 diphosphotransferase activity IEP Enrichment
MF GO:0016779 nucleotidyltransferase activity IEP Enrichment
MF GO:0016787 hydrolase activity IEP Enrichment
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Enrichment
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Enrichment
MF GO:0016849 phosphorus-oxygen lyase activity IEP Enrichment
MF GO:0016874 ligase activity IEP Enrichment
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
MF GO:0017111 nucleoside-triphosphatase activity IEP Enrichment
BP GO:0018130 heterocycle biosynthetic process IEP Enrichment
MF GO:0019001 guanyl nucleotide binding IEP Enrichment
BP GO:0019438 aromatic compound biosynthetic process IEP Enrichment
BP GO:0019752 carboxylic acid metabolic process IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
MF GO:0032561 guanyl ribonucleotide binding IEP Enrichment
BP GO:0032774 RNA biosynthetic process IEP Enrichment
MF GO:0032977 membrane insertase activity IEP Enrichment
MF GO:0034062 5'-3' RNA polymerase activity IEP Enrichment
BP GO:0034470 ncRNA processing IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
BP GO:0043038 amino acid activation IEP Enrichment
BP GO:0043039 tRNA aminoacylation IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
BP GO:0043170 macromolecule metabolic process IEP Enrichment
BP GO:0043436 oxoacid metabolic process IEP Enrichment
BP GO:0043647 inositol phosphate metabolic process IEP Enrichment
BP GO:0044237 cellular metabolic process IEP Enrichment
BP GO:0044238 primary metabolic process IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Enrichment
BP GO:0044281 small molecule metabolic process IEP Enrichment
BP GO:0046040 IMP metabolic process IEP Enrichment
BP GO:0046164 alcohol catabolic process IEP Enrichment
BP GO:0046174 polyol catabolic process IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
BP GO:0046838 phosphorylated carbohydrate dephosphorylation IEP Enrichment
BP GO:0046855 inositol phosphate dephosphorylation IEP Enrichment
MF GO:0046983 protein dimerization activity IEP Enrichment
MF GO:0052689 carboxylic ester hydrolase activity IEP Enrichment
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Enrichment
BP GO:0071545 inositol phosphate catabolic process IEP Enrichment
BP GO:0071704 organic substance metabolic process IEP Enrichment
BP GO:0090304 nucleic acid metabolic process IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:0097747 RNA polymerase activity IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
MF GO:0140104 molecular carrier activity IEP Enrichment
MF GO:0140597 protein carrier activity IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
BP GO:1901362 organic cyclic compound biosynthetic process IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
BP GO:1901564 organonitrogen compound metabolic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
BP GO:1901616 organic hydroxy compound catabolic process IEP Enrichment
BP GO:1901657 glycosyl compound metabolic process IEP Enrichment
MF GO:1990817 RNA adenylyltransferase activity IEP Enrichment
InterPro domains Description Start Stop
IPR002792 TRAM_dom 378 440
IPR007197 rSAM 151 325
IPR013848 Methylthiotransferase_N 4 104
UniProtKB P0AEI1