AAC75085 (hisA, b2024)

Aliases : hisA, b2024

Description : N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'-phosphoribosyl)-4-imidazolecarboxamide isomerase [Ensembl]. Histidine biosynthesis protein [Interproscan].

Gene families : OG_02_0000826 (OrthoFinder) Phylogenetic Tree(s): OG0000826_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC75085
Cluster	HCCA: Cluster_32

Target	Alias	Description	ECC score	Gene Family Method
AAL20980	STM2076, hisA	N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'-phosphor...	0.11	OrthoFinder
AGT23513	N559_1777	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methyliden...	0.09	OrthoFinder
AKI48513	hisA, L2625_00577	phosphoribosylformimino-5-aminoimidazole carboxamide...	0.05	OrthoFinder
CCL17755	hisA, BN171_1750016	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methyliden...	0.06	OrthoFinder
CCP44367	hisA, Rv1603	Probable phosphoribosylformimino-5-aminoimidazole...	0.05	OrthoFinder
CPC67992	hisA, ERS093114_01040	Phosphoribosylformimino-5-aminoimidazole carboxamide...	0.5	OrthoFinder
CRP48862	hisA	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methyliden...	0.03	OrthoFinder
EDJ91519	CGSHi22421_07107	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methyliden...	0.12	OrthoFinder
KNA53865	VCV51_030803	histidine biosynthesis protein [Ensembl]. Histidine...	0.08	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0000105	histidine biosynthetic process	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006547	histidine metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004399	histidinol dehydrogenase activity	IEP	Enrichment
MF	GO:0004424	imidazoleglycerol-phosphate dehydratase activity	IEP	Enrichment
MF	GO:0004635	phosphoribosyl-AMP cyclohydrolase activity	IEP	Enrichment
BP	GO:0006553	lysine metabolic process	IEP	Enrichment
MF	GO:0008839	4-hydroxy-tetrahydrodipicolinate reductase	IEP	Enrichment
BP	GO:0009066	aspartate family amino acid metabolic process	IEP	Enrichment
BP	GO:0009067	aspartate family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009085	lysine biosynthetic process	IEP	Enrichment
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Enrichment
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEP	Enrichment
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEP	Enrichment
MF	GO:0016835	carbon-oxygen lyase activity	IEP	Enrichment
MF	GO:0016836	hydro-lyase activity	IEP	Enrichment
MF	GO:0019238	cyclohydrolase activity	IEP	Enrichment
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Enrichment
BP	GO:0046451	diaminopimelate metabolic process	IEP	Enrichment
MF	GO:0051287	NAD binding	IEP	Enrichment
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006062	His_biosynth	1	234

External Links

UniProtKB	P10371

AAC75085 (hisA, b2024)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation