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GO:0004222: metalloendopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE]


There are 1163 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_8 Escherichia coli 4.23 % 0.000377 0.013276
Cluster_27 Neisseria gonorrhoeae 50.0 % 0.003703 0.022746
Cluster_47 Pseudomonas aeruginosa 2.07 % 0.003287 0.032495
Sequences (1163) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms