GO:0004252: serine-type endopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]

There are 860 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_12 Clostridioides difficile 1.62 % 0.001082 0.01352
Cluster_23 Haemophilus influenzae 5.66 % 0.00078 0.043679
Cluster_17 Staphylococcus aureus 5.13 % 2.3e-05 0.005096
Sequences (860) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms