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Heatmap: Cluster_9 (HCCA)

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(Showing raw values)

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Gene
BHI
Basal Medium
CD196,BHI
CD196,Basal Medium
CD196,Log,BHI
ClnR mutant
LB-CD16
Log,BHI
LuxS KO
ND-CD12
ND-CD13
ND-CD17
R20291
R20291,BHI
R20291,Basal Medium
R20291,Heme+
R20291,Log
R20291,Log,BHI
Strain 630
Strain 630,BHI
Strain 630,Basal Medium
Strain 630,Faecal water+
Strain 630,HPUra+
Strain 630,Lag
Strain 630,Log
Strain 630,Log,BHI
Strain 630,Sporulating
TW11
UK1
CCL16947 (BN171_1020014)
 3.16 24.49 5.82 44.13 6.6 3.0 132.72 4.08 13.86 65.17 59.86 87.33 12.38 3.69 67.55 6.34 93.33 8.13 32.07 4.0 37.45 10.67 8.26 18.79 51.25 4.99 55.23 3.5 28.96
CCL16948 (BN171_1020015)
 0.45 3.47 1.15 5.73 0.67 3.75 92.63 0.17 7.76 66.91 56.13 71.98 14.0 0.76 10.56 7.48 91.77 0.67 24.48 0.3 8.22 5.74 8.53 16.67 46.79 0.26 68.3 4.3 20.8
CCL16950 (BN171_1020017)
 2.54 36.58 3.82 66.28 5.5 3.69 195.65 3.12 10.53 80.08 93.66 113.16 14.54 3.0 92.57 5.47 90.66 7.54 32.04 2.97 51.22 14.32 7.82 21.06 51.26 3.48 142.32 4.21 49.56
CCL16951 (BN171_1020018)
 3.29 62.29 7.08 97.74 9.35 3.73 202.67 5.71 12.14 105.78 97.96 135.39 18.3 4.05 142.41 10.2 131.0 12.03 39.98 3.86 63.35 12.18 9.54 28.58 66.69 3.42 210.87 7.59 43.8
CCL17339 (BN171_1440023)
 0.72 5.55 5.48 4.35 3.64 1.46 0.0 1.86 0.0 0.0 0.0 0.0 3.2 0.98 3.41 1.33 163.88 3.32 3.5 3.69 2.34 4.02 0.81 1.27 0.37 0.7 0.48 11.19 0.0
CCL17340 (BN171_1450001)
 2.25 2.34 1.95 3.89 2.55 1.74 2.06 1.83 1.36 1.95 1.78 1.81 4.51 1.49 2.26 7.7 21.11 1.62 2.63 1.59 2.14 1.46 2.48 2.0 3.25 1.59 1.19 4.56 0.64
CCL17392 (BN171_1480004)
 27.02 5.74 57.5 73.96 27.8 59.73 250.8 9.94 9.52 85.14 15.55 102.18 12.98 50.07 4.42 4.24 947.32 5.16 29.77 17.15 66.98 0.0 50.55 11.84 60.15 20.97 32.65 38.56 0.0
CCL17393 (BN171_1480005)
 0.0 0.0 0.0 0.0 0.0 1.89 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.42 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
CCL17528 (BN171_1540007)
 0.0 0.0 0.0 2.84 0.0 2.57 30.52 0.0 0.0 15.47 18.53 6.02 24.29 2.02 10.69 0.0 24.2 6.19 26.74 0.0 1.47 0.0 44.85 0.0 3.22 0.0 2.23 79.0 0.0
CCL17529 (BN171_1540008)
 1.64 1.9 2.02 1.95 1.88 0.97 9.82 0.49 0.33 3.6 15.1 5.3 16.94 7.13 10.67 4.95 6.3 5.95 14.51 1.04 0.53 1.18 26.09 0.78 0.98 0.14 2.25 18.66 5.5
CCL17590 (BN171_160006)
 0.0 0.0 0.0 0.02 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.13 0.0 0.0 0.0 0.16 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2
CCL17619 (BN171_1640009)
 278.4 187.71 309.69 361.14 235.38 333.38 287.58 101.11 1725.22 292.54 299.11 243.59 569.84 294.09 263.75 378.51 1834.18 219.14 500.67 353.82 377.98 115.03 662.11 641.26 538.53 170.67 151.0 398.72 249.4
CCL17705 (fdxA)
 224.69 284.47 148.99 138.3 97.6 453.29 0.0 214.98 66.37 0.0 0.0 0.0 406.28 100.98 181.59 0.0 55.83 165.1 183.53 160.71 264.71 20.08 105.25 98.41 192.01 158.12 59.82 816.95 0.0
CCL17726 (BN171_1740001)
 41029.9 130955.5 42360.25 70104.6 43375.8 5144.26 11553.67 74029.35 21852.4 6547.67 10947.62 12199.35 14630.12 9181.12 89652.8 5870.3 71879.5 46906.15 21570.2 29061.15 25800.3 2682.03 34079.05 79474.32 17273.12 20460.6 31290.41 14827.42 15916.6
CCL17945 (BN171_1970014)
 572.55 222.29 704.4 527.99 434.35 77.8 211.58 68.39 99.57 130.19 160.96 184.45 169.7 88.19 197.99 39.55 1454.31 322.35 378.55 157.69 224.6 0.0 609.82 375.12 34.47 67.0 249.59 718.13 160.79
CCL17971 (BN171_1980009)
 19.04 17.8 30.07 54.46 13.67 22.34 2185.47 3.62 5270.29 1454.26 407.36 374.27 930.87 10.48 9.74 158.12 17479.64 10.62 1415.63 20.61 192.59 7.77 326.22 763.42 410.17 3.12 2850.88 2473.86 347.32
CCL18067 (BN171_210003)
 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.37 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
CCL18142 (BN171_2120002)
 13.51 124.16 8.29 89.5 8.66 7.75 123.04 8.73 29.28 125.72 119.61 95.96 66.11 23.76 231.51 21.12 180.45 38.22 42.06 17.62 221.23 16.95 7.73 46.23 26.71 7.12 146.26 145.83 118.92
CCL18184 (BN171_2140026)
 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.02 0.0 0.0 0.0 0.0 0.0 0.0 0.91 0.79 0.0 0.84 0.0 0.0
CCL18348 (BN171_2220035)
 0.0 0.31 4.81 6.58 6.34 2.13 1.5 0.24 1.53 15.19 16.11 21.5 32.15 2.04 1.49 8.05 850.12 1.3 30.0 4.65 4.56 0.0 75.24 10.1 17.6 0.85 0.52 15.93 17.34
CCL18350 (BN171_2220037)
 0.0 0.0 0.0 0.0 0.0 40.18 0.0 0.0 0.0 0.0 0.0 0.0 78.47 0.0 0.0 0.0 444.08 0.0 5.21 0.0 0.0 0.0 0.0 143.13 121.57 0.0 27.16 5.62 0.0
CCL18378 (BN171_2270001)
 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.47 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0
CCL18384 (BN171_2270007)
 0.0 0.0 0.0 0.0 0.0 1.58 0.0 0.0 0.0 0.0 0.0 0.0 3.48 0.0 1.92 0.0 52.72 0.0 1.66 0.0 0.0 0.0 0.0 4.89 0.53 0.0 9.75 0.0 0.0
CCL18385 (BN171_2270008)
 49.01 77.44 161.85 91.23 62.88 38.57 3114.16 42.5 2827.82 1491.89 1847.78 1848.24 632.95 29.76 60.53 140.48 4220.6 49.17 848.27 124.09 85.59 7.77 1455.96 1833.48 254.14 16.88 393.41 1487.22 2418.92
CCL18496 (BN171_240001)
 2.86 2.31 2.9 2.58 1.67 2.3 15.11 0.89 8.02 7.01 3.84 6.29 6.26 2.37 2.53 5.2 50.13 2.89 21.34 2.83 2.08 3.3 13.95 3.34 3.61 1.17 7.64 8.88 4.46
CCL18497 (BN171_240002)
 0.0 0.0 0.96 0.0 0.0 1.86 3.57 0.0 4.63 3.62 0.0 0.0 4.1 0.0 0.0 6.99 16.73 1.19 17.43 0.0 2.58 0.0 10.44 3.24 3.98 0.0 3.07 8.87 0.0
CCL18498 (BN171_240003)
 3.95 2.28 2.66 3.26 3.59 4.13 4.37 2.53 10.02 2.29 2.89 3.1 4.96 2.72 3.36 5.72 38.6 3.97 26.67 2.4 2.96 9.12 14.41 5.82 6.26 2.16 5.02 7.75 1.56
CCL18499 (BN171_240004)
 0.49 0.25 0.54 0.51 0.41 1.17 2.16 0.08 1.26 1.34 0.41 0.25 2.08 0.21 0.3 1.33 25.92 0.38 22.13 0.91 1.62 1.19 13.57 3.77 4.68 0.73 3.98 6.65 0.73
CCL18650 (BN171_2480025)
 67.65 8.84 281.62 101.43 79.38 163.29 314.84 5.11 5376.12 286.0 376.27 259.11 1320.91 242.64 67.87 649.01 4860.59 58.35 396.5 352.07 574.91 29.61 490.15 823.48 858.48 27.32 6751.26 3315.65 298.35
CCL18744 (4hbD)
 19.01 22.85 16.05 25.51 32.96 924.52 4068.18 46.16 129.82 4219.66 3528.9 2515.38 420.3 5.72 27.09 25.01 1706.59 11.02 1026.33 55.54 53.01 71.09 1286.85 56.17 1111.82 208.31 211.3 88.93 1638.64
CCL18745 (cat)
 19.45 26.6 16.21 28.65 38.34 924.28 3695.76 48.01 114.27 3541.86 3112.78 2102.39 399.61 4.57 31.38 17.2 1366.87 13.19 1000.0 41.24 47.86 119.5 1141.62 49.62 869.07 171.0 153.07 47.25 1318.72
CCL18746 (BN171_2600005)
 58.96 58.09 56.04 72.11 106.9 3001.06 4106.77 123.92 173.98 3230.2 2940.11 2032.49 591.91 13.09 55.51 20.91 3222.45 33.53 1733.73 115.71 88.6 106.63 1231.64 38.92 1214.81 515.0 234.53 49.35 1502.46
CCL18747 (abfD)
 16.14 28.68 14.02 29.72 32.6 913.3 4422.63 47.42 185.39 3710.73 3321.88 2436.97 557.11 7.06 32.69 22.08 1544.9 11.44 1060.36 46.35 54.79 103.28 905.18 30.91 934.09 183.52 191.8 42.6 1715.04
CCL18748 (sucD)
 12.61 2.71 12.51 5.38 46.78 1070.46 3903.11 46.75 219.86 3541.23 3262.03 2290.03 316.19 1.53 1.53 6.22 924.57 2.87 1183.71 45.71 19.51 23.29 975.06 30.5 749.74 233.15 205.11 46.07 1746.58
CCL18749 (cat)
 7.41 1.83 6.95 4.44 35.41 620.98 2064.87 35.14 132.01 2299.2 2074.73 1386.14 188.53 0.88 1.11 3.26 402.55 1.69 831.98 27.42 13.59 12.84 847.05 16.29 505.75 162.23 126.16 41.87 1027.21
CCL18750 (BN171_2600009)
 4.34 1.26 6.15 3.78 27.56 440.5 1544.76 23.28 106.47 1691.13 1466.24 970.53 112.54 0.25 0.42 3.59 242.97 0.65 584.51 22.04 14.76 7.8 777.63 16.99 323.06 117.67 56.3 36.97 757.32
CCL18823 (BN171_2670005)
 0.64 4.17 0.8 3.88 0.82 1.49 4.47 0.66 4.09 2.82 3.68 2.92 4.55 0.55 5.46 3.33 38.87 0.57 4.84 0.76 9.64 3.75 4.41 2.4 0.99 0.65 6.64 5.32 3.75
CCL18824 (BN171_2670006)
 1.21 4.69 1.66 6.3 1.02 0.5 1.79 1.68 1.76 1.17 0.4 2.08 2.31 0.79 5.6 3.06 11.3 1.75 3.15 1.02 8.55 0.0 3.91 2.15 0.56 0.74 1.73 4.59 3.89
CCL18825 (BN171_2670007)
 0.97 0.75 0.55 3.42 0.47 0.16 1.21 0.65 1.63 0.77 1.11 1.19 1.95 0.2 2.73 3.3 10.39 0.49 1.88 0.96 3.57 0.0 2.19 1.54 0.17 0.31 1.12 5.38 1.27
CCL18826 (BN171_2670008)
 0.05 0.08 0.22 0.35 0.15 0.19 1.03 0.02 0.73 0.71 1.39 1.04 1.6 0.14 0.33 1.13 5.38 0.09 1.42 0.08 1.6 0.0 1.58 0.54 0.22 0.06 0.6 1.88 1.56
CCL18827 (BN171_2670009)
 0.32 5.4 0.21 5.15 0.23 0.29 3.73 0.34 2.5 1.01 1.45 1.65 2.26 0.25 8.19 3.38 23.66 0.46 3.2 0.24 11.2 1.17 0.44 0.65 0.32 0.22 4.85 3.93 2.26
CCL18828 (BN171_2670010)
 0.05 1.7 0.0 1.65 0.05 0.11 2.8 0.04 3.95 2.96 2.38 0.53 1.67 0.0 2.64 2.08 27.7 0.34 2.2 0.0 3.21 0.0 0.38 0.54 0.42 0.14 3.47 3.36 3.25
CCL18927 (BN171_2720027)
 0.85 0.1 4.9 3.29 4.1 4.97 21.92 0.15 25.94 64.56 86.09 53.03 43.82 4.45 0.57 26.53 25.08 1.28 62.2 3.61 2.98 8.69 112.59 22.04 25.71 1.06 0.85 115.76 106.62
CCL18928 (LinCd)
 13.1 3.04 13.29 18.22 15.45 5.2 27.16 6.72 37.44 85.38 107.47 64.94 74.12 11.02 6.05 51.08 58.59 17.38 101.86 10.71 10.36 81.34 161.42 65.22 75.26 9.56 8.62 73.14 110.06
CCL19205 (BN171_2950007)
 8.51 88.43 18.6 128.59 21.65 19.21 258.96 7.76 3.69 124.58 170.49 255.39 49.72 29.26 220.75 9.93 294.13 46.77 35.42 18.55 103.09 10.84 14.01 33.56 60.65 20.63 198.11 8.82 50.73
CCL19206 (BN171_2950008)
 2.25 13.06 4.56 23.64 7.81 8.05 84.43 0.9 0.27 63.12 63.39 93.41 23.89 7.57 44.12 3.87 117.7 12.39 17.58 3.63 21.58 7.48 6.4 13.53 28.01 5.44 71.2 4.95 18.73
CCL19407 (BN171_3100013)
 0.52 0.07 2.71 2.62 4.72 24.39 14.67 0.31 4.44 27.17 19.88 19.08 16.38 2.49 0.47 24.65 11.92 2.64 48.44 5.98 13.61 3.32 66.0 31.98 34.92 2.81 2.35 57.56 18.27
CCL19460 (BN171_3150023)
 11.37 3.17 9.55 4.32 5.2 11.42 20.22 4.4 3.55 23.02 22.11 20.52 13.01 9.98 3.55 17.7 4.76 8.18 39.34 10.37 3.3 7.42 23.19 4.74 17.52 6.38 1.73 39.32 27.56
CCL19461 (BN171_3150024)
 17.02 5.57 15.8 6.83 11.1 18.89 9.56 11.47 4.7 17.44 12.47 12.13 12.35 19.75 4.74 20.57 5.36 14.19 30.89 15.14 3.19 4.18 17.29 3.26 14.5 8.85 1.01 42.76 8.79
CCL19533 (BN171_3220002)
 2.13 4.79 25.09 65.39 35.05 5.37 117.8 2.37 2.94 9.2 10.15 32.57 41.31 2.33 6.47 35.38 5.96 5.07 50.33 14.62 15.02 43.35 17.36 184.54 9.64 9.68 3.66 196.05 12.8
CCL19534 (BN171_3220003)
 3.95 5.16 4.71 6.46 24.65 7.34 126.94 9.62 0.0 8.48 10.59 34.54 13.71 6.16 8.06 3.24 0.36 19.03 51.2 76.97 9.23 0.35 3.91 118.78 5.9 48.54 0.79 110.45 11.79
CCL19584 (BN171_3270022)
 1.49 0.48 2.42 1.31 1.68 6.06 3.32 2.3 2.69 11.43 6.65 5.44 13.01 4.16 1.32 13.65 12.09 2.59 23.69 0.72 1.27 1.31 24.11 12.24 8.19 0.15 6.3 55.71 1.41
CCL19621 (BN171_3310001)
 68.73 33.53 39.28 21.57 28.01 77.17 34.69 35.76 54.25 38.56 50.73 43.2 106.91 70.03 28.25 88.27 154.46 56.64 195.12 39.17 40.62 7.29 145.62 89.5 105.23 14.21 67.43 215.56 85.7
CCL19622 (BN171_3310002)
 7.54 1.37 5.66 5.51 3.0 2.31 2.14 1.55 2.38 6.89 2.98 5.4 6.18 8.41 1.67 2.86 13.87 3.55 21.27 2.73 5.16 3.95 16.28 7.84 7.93 1.66 8.76 18.66 8.86
CCL19737 (rgaR)
 15.86 14.23 29.57 26.68 33.0 44.71 65.64 16.47 154.47 99.12 100.94 101.88 93.97 26.08 18.08 161.0 116.52 21.76 173.91 55.5 55.84 27.41 213.84 157.14 118.07 27.6 64.81 242.56 89.47
CCL19746 (pstC)
 5.04 1.04 6.46 2.43 1.64 0.42 4.56 1.0 2.89 3.78 0.98 1.81 10.9 21.23 1.49 3.01 1.45 1.3 12.54 23.7 2.21 2.52 14.38 3.12 0.79 0.75 5.7 23.37 2.42
CCL19803 (BN171_3490006)
 89.24 35.33 56.86 51.06 62.87 47.32 40.37 26.39 57.2 64.47 70.89 60.02 98.86 65.29 38.8 130.58 77.21 52.51 105.48 86.53 56.3 3.44 141.85 93.98 136.62 43.2 68.25 98.46 62.2
CCL20035 (BN171_3670018)
 2753.69 713.07 2144.19 1471.13 1044.12 1969.21 2874.89 633.24 15509.57 2287.11 3919.47 4076.24 5039.88 2279.39 548.68 2514.73 23199.95 1051.01 12071.48 2474.91 1385.72 745.29 11387.73 5179.49 3295.34 827.92 2674.86 14078.57 5655.13
CCL20038 (BN171_3670021)
 23.31 8.43 21.23 10.22 14.3 73.01 0.0 39.61 3.54 0.0 0.0 0.0 174.39 34.09 2.32 0.0 63.02 33.15 109.11 26.22 7.81 0.0 135.3 96.66 243.95 11.9 5.29 376.59 0.0
CCL20212 (BN171_380007)
 0.0 0.0 0.3 0.0 0.34 23.38 8.9 0.24 54.12 30.88 21.37 14.46 70.48 2.31 0.0 80.97 53.03 0.0 63.72 0.66 0.74 3.23 47.13 29.67 20.25 0.0 27.57 172.19 31.21
CCL20280 (BN171_40008)
 213.89 96.88 305.55 270.79 524.64 106.85 252.86 336.73 141.23 316.29 305.31 288.1 430.17 745.85 139.78 1067.0 214.09 403.73 715.59 1026.45 766.36 0.0 675.05 37.11 104.97 226.24 11.87 1245.17 290.46
CCL20414 (BN171_440002)
 24.35 17.3 24.46 13.99 18.13 10.06 15.18 21.68 7.23 11.25 13.05 17.5 12.89 10.29 10.03 19.26 8.66 16.56 18.69 12.99 6.58 3.51 21.12 12.01 12.82 9.37 1.93 28.0 14.05
CCL20432 (BN171_450008)
 565.94 244.18 393.92 223.45 283.43 139.06 768.28 183.49 743.45 737.88 884.11 586.87 594.55 295.13 172.95 505.31 1100.62 263.32 1096.23 610.47 435.32 176.16 800.78 680.87 405.17 235.42 926.27 565.12 819.32
CCL20437 (BN171_460001)
 0.9 6.73 2.13 22.19 1.91 1.37 25.86 1.03 1.54 13.75 7.39 7.56 18.29 0.87 1.97 32.58 40.84 1.16 13.25 1.08 6.41 2.29 21.74 1.92 1.33 0.39 17.14 10.34 2.01
CCL20474 (BN171_530001)
 98.08 64.58 80.18 85.72 100.74 78.47 18.42 100.6 116.75 28.31 49.82 101.12 176.7 181.64 60.34 18.04 384.45 82.91 324.21 19.26 47.8 0.0 299.96 95.64 76.72 20.12 109.05 264.19 77.68
CCL20490 (BN171_570003)
 433.87 14991.0 243.55 3955.04 265.16 52.75 723.06 321.08 1837.64 755.16 184.66 190.98 353.24 120.45 2119.7 267.09 6363.67 204.56 809.92 218.49 1188.07 40.92 365.8 1153.77 214.26 94.08 3821.09 39.19 18.63
CCL20491 (BN171_570004)
 0.2 17.81 0.97 13.2 0.19 5.6 758.69 0.0 262.42 587.52 140.25 189.78 265.46 0.8 3.39 102.97 1507.76 0.21 208.35 1.09 6.52 3.22 105.53 94.54 21.79 0.0 347.36 23.97 44.91
CCL20492 (BN171_580001)
 4.25 17.35 5.18 16.1 6.09 2.62 30.36 3.78 12.13 56.38 21.5 26.3 18.16 2.06 5.74 25.94 52.43 2.33 10.02 0.7 2.87 21.32 3.41 1.33 1.78 0.55 13.7 2.67 11.24
CCL20493 (BN171_580002)
 5.0 25.4 5.61 19.12 7.64 4.07 42.47 5.75 11.17 85.1 32.85 41.88 25.61 1.78 7.69 32.02 45.34 3.06 16.91 1.94 4.54 30.72 8.19 3.65 3.95 1.49 21.06 5.25 18.21
CCL20612 (BN171_730002)
 1.73 3.6 8.62 2.37 0.0 26.53 0.0 4.61 21.01 0.0 0.0 0.0 103.22 3.04 2.31 0.0 91.25 0.0 32.31 0.0 2.46 0.0 53.6 69.83 46.83 0.0 32.49 260.81 0.0
CCL20613 (BN171_740001)
 7.49 18.4 24.78 33.37 20.89 171.78 87.01 23.79 128.81 119.69 69.71 137.94 121.83 24.34 20.41 50.83 354.11 15.67 411.2 153.11 191.42 7.36 421.8 266.81 173.08 119.71 207.5 873.83 51.36
CCL20646 (BN171_810002)
 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.24 0.0 0.14 0.0 0.0 0.0 0.0 0.0 1.02 0.0 1.15 39.52 0.0
CCL20648 (tcdC)
 5.56 5.01 4.32 10.01 4.53 19.34 128.34 5.1 5.87 77.48 23.41 43.4 17.7 4.64 6.91 8.45 7.48 10.21 49.92 33.72 33.56 23.68 49.7 50.07 34.38 25.68 32.55 73.48 16.81
CCL20718 (BN171_960010)
 2.53 2.81 2.74 6.94 0.0 52.89 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 9.71 0.0 311.7 0.0 10.23 0.0 20.7 0.0 0.0 37.63 19.77 0.0 234.4 5.93 0.0

Details

Raw expression values (TPM normalized), Green cells indicate low expression and red high. (Dark gray cells indicate missing values)