AKI49412 (mvaS, L2625_01512)

Aliases : mvaS, L2625_01512

Description : hydroxymethylglutaryl-CoA synthase [Ensembl]. Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain [Interproscan].

Gene families : OG_02_0002535 (OrthoFinder) Phylogenetic Tree(s): OG0002535_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI49412
Cluster	HCCA: Cluster_26

Target	Alias	Description	ECC score	Gene Family Method	Actions
AAL00374	spr1571, mvaS	3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase...	0.06	OrthoFinder
CPC63667	mvaS, ERS093114_00915	Hydroxymethylglutaryl-CoA synthase [Ensembl]....	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004421	hydroxymethylglutaryl-CoA synthase activity	IEA	Interproscan
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006720	isoprenoid metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008299	isoprenoid biosynthetic process	IEA	Interproscan
BP	GO:0008610	lipid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016746	acyltransferase activity	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
MF	GO:0046912	acyltransferase, acyl groups converted into alkyl on transfer	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003725	double-stranded RNA binding	IEP	Enrichment
MF	GO:0004096	catalase activity	IEP	Enrichment
MF	GO:0004345	glucose-6-phosphate dehydrogenase activity	IEP	Enrichment
MF	GO:0004357	glutamate-cysteine ligase activity	IEP	Enrichment
MF	GO:0004601	peroxidase activity	IEP	Enrichment
MF	GO:0004602	glutathione peroxidase activity	IEP	Enrichment
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEP	Enrichment
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Enrichment
MF	GO:0004784	superoxide dismutase activity	IEP	Enrichment
BP	GO:0006098	pentose-phosphate shunt	IEP	Enrichment
BP	GO:0006740	NADPH regeneration	IEP	Enrichment
BP	GO:0006749	glutathione metabolic process	IEP	Enrichment
BP	GO:0006750	glutathione biosynthetic process	IEP	Enrichment
BP	GO:0006784	heme A biosynthetic process	IEP	Enrichment
BP	GO:0006801	superoxide metabolic process	IEP	Enrichment
BP	GO:0006979	response to oxidative stress	IEP	Enrichment
MF	GO:0008883	glutamyl-tRNA reductase activity	IEP	Enrichment
BP	GO:0010035	response to inorganic substance	IEP	Enrichment
BP	GO:0010038	response to metal ion	IEP	Enrichment
MF	GO:0016209	antioxidant activity	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IEP	Enrichment
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	IEP	Enrichment
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Enrichment
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Enrichment
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Enrichment
BP	GO:0019184	nonribosomal peptide biosynthetic process	IEP	Enrichment
MF	GO:0030151	molybdenum ion binding	IEP	Enrichment
MF	GO:0033743	peptide-methionine (R)-S-oxide reductase activity	IEP	Enrichment
CC	GO:0042597	periplasmic space	IEP	Enrichment
MF	GO:0043169	cation binding	IEP	Enrichment
BP	GO:0046160	heme a metabolic process	IEP	Enrichment
MF	GO:0046429	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity	IEP	Enrichment
BP	GO:0046688	response to copper ion	IEP	Enrichment
MF	GO:0046872	metal ion binding	IEP	Enrichment
MF	GO:0050661	NADP binding	IEP	Enrichment
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Enrichment
MF	GO:0052592	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Enrichment
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013746	HMG_CoA_synt_C_dom	264	353
IPR013746	HMG_CoA_synt_C_dom	178	247
IPR013528	HMG_CoA_synth_N	2	164

External Links

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AKI49412 (mvaS, L2625_01512)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation