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GO:0003824: catalytic activity (Molecular function)

"Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [GOC:vw, ISBN:0198506732]


There are 15560 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_14 Clostridioides difficile 28.05 % 0.000423 0.027059
Cluster_2 Clostridioides difficile 20.36 % 0.003029 0.015982
Cluster_26 Enterococcus faecalis 43.9 % 0.000617 0.007814
Cluster_22 Escherichia coli 38.27 % 0.004569 0.039594
Cluster_48 Escherichia coli 100.0 % 0.015187 0.016356
Cluster_23 Escherichia coli 43.48 % 0.004068 0.026994
Cluster_6 Escherichia coli 48.15 % 4e-06 0.000534
Cluster_41 Escherichia coli 39.08 % 0.002031 0.013553
Cluster_31 Escherichia coli 39.39 % 0.005817 0.031781
Cluster_37 Escherichia coli 39.66 % 0.000239 0.001888
Cluster_3 Haemophilus influenzae 32.64 % 0.002095 0.046815
Cluster_26 Klebsiella pneumoniae 39.05 % 1.6e-05 0.000234
Cluster_29 Klebsiella pneumoniae 31.98 % 6.4e-05 0.003395
Cluster_18 Klebsiella pneumoniae 38.96 % 0.000228 0.014952
Cluster_16 Klebsiella pneumoniae 36.17 % 2e-05 0.001817
Cluster_44 Klebsiella pneumoniae 35.82 % 4.6e-05 0.000354
Cluster_30 Klebsiella pneumoniae 30.77 % 0.00161 0.023338
Cluster_63 Klebsiella pneumoniae 80.0 % 0.008099 0.021298
Cluster_8 Listeria monocytogenes 40.37 % 0.000508 0.006457
Cluster_18 Listeria monocytogenes 40.15 % 0.000161 0.000929
Cluster_9 Listeria monocytogenes 39.19 % 0.007391 0.03675
Cluster_7 Listeria monocytogenes 49.21 % 4.8e-05 0.00054
Cluster_48 Mycobacterium tuberculosis 100.0 % 0.0 0.0
Cluster_31 Mycobacterium tuberculosis 35.0 % 0.000129 0.03206
Cluster_8 Neisseria gonorrhoeae 44.0 % 4.5e-05 0.014275
Cluster_12 Neisseria gonorrhoeae 40.52 % 1e-06 9e-06
Cluster_7 Neisseria gonorrhoeae 39.68 % 1.7e-05 0.006692
Cluster_22 Pseudomonas aeruginosa 27.75 % 0.004584 0.018512
Cluster_72 Pseudomonas aeruginosa 100.0 % 0.008182 0.031559
Cluster_47 Pseudomonas aeruginosa 37.24 % 1e-06 0.000395
Cluster_26 Pseudomonas aeruginosa 33.33 % 0.00689 0.045645
Cluster_51 Pseudomonas aeruginosa 36.9 % 0.000261 0.001777
Cluster_35 Pseudomonas aeruginosa 28.5 % 0.002613 0.021951
Cluster_6 Salmonella enterica 39.9 % 0.0 2e-06
Cluster_3 Salmonella enterica 41.76 % 3.7e-05 0.000953
Cluster_47 Salmonella enterica 44.9 % 0.000486 0.006055
Cluster_31 Salmonella enterica 32.74 % 0.000322 0.002745
Cluster_35 Salmonella enterica 41.55 % 0.0 5.4e-05
Cluster_5 Staphylococcus aureus 35.14 % 4.7e-05 0.000563
Cluster_14 Staphylococcus aureus 54.39 % 0.0 3.7e-05
Cluster_11 Staphylococcus aureus 40.54 % 1.4e-05 0.000782
Cluster_14 Streptococcus pneumoniae 23.66 % 0.004883 0.030326
Cluster_3 Streptococcus pneumoniae 28.28 % 1.6e-05 0.004422
Cluster_5 Streptococcus pyogenes 28.92 % 0.00034 0.014218
Cluster_2 Streptococcus pyogenes 24.58 % 0.001626 0.026152
Cluster_16 Streptococcus pyogenes 30.0 % 0.0031 0.03238
Cluster_12 Vibrio cholerae 19.8 % 0.002686 0.046258
Sequences (15560) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !