CPC90060 (metH, ERS093114_01571)

Aliases : metH, ERS093114_01571

Description : 5%2C10-methylenetetrahydrofolate reductase-like homocysteine-binding domain protein [Ensembl]. Homocysteine S-methyltransferase, Methylenetetrahydrofolate reductase [Interproscan].

Gene families : OG_02_0000961 (OrthoFinder) Phylogenetic Tree(s): OG0000961_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CPC90060
Cluster	HCCA: Cluster_25

Target	Alias	Description	ECC score	Gene Family Method
AAC73364	mmuM, b0261	CP4-6 prophage; S-methylmethionine:homocysteine...	0.06	OrthoFinder
AAL23012	STM4188, metH	B12-dependent homocysteine-N5-methyltetrahydrofolate...	0.02	OrthoFinder
AGT25728	N559_4102	homocysteine methyltransferase [Ensembl]....	0.02	OrthoFinder
AKI49674	L2625_01789	bifunctional homocysteine S-methyltransferase...	0.05	OrthoFinder
CRO36716	metH	Methionine synthase [Ensembl]. B12 binding domain,...	0.06	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006555	methionine metabolic process	IEA	Interproscan
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009066	aspartate family amino acid metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	None	Extended
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0055114	obsolete oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000097	sulfur amino acid biosynthetic process	IEP	Enrichment
MF	GO:0003871	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	IEP	Enrichment
MF	GO:0004061	arylformamidase activity	IEP	Enrichment
MF	GO:0005283	amino acid:sodium symporter activity	IEP	Enrichment
MF	GO:0005342	organic acid transmembrane transporter activity	IEP	Enrichment
MF	GO:0005343	organic acid:sodium symporter activity	IEP	Enrichment
MF	GO:0005416	amino acid:cation symporter activity	IEP	Enrichment
BP	GO:0006534	cysteine metabolic process	IEP	Enrichment
BP	GO:0006568	tryptophan metabolic process	IEP	Enrichment
BP	GO:0006569	tryptophan catabolic process	IEP	Enrichment
BP	GO:0006576	cellular biogenic amine metabolic process	IEP	Enrichment
BP	GO:0006586	indolalkylamine metabolic process	IEP	Enrichment
BP	GO:0006811	ion transport	IEP	Enrichment
BP	GO:0006812	cation transport	IEP	Enrichment
BP	GO:0006814	sodium ion transport	IEP	Enrichment
BP	GO:0006820	anion transport	IEP	Enrichment
BP	GO:0006865	amino acid transport	IEP	Enrichment
MF	GO:0008172	S-methyltransferase activity	IEP	Enrichment
MF	GO:0008270	zinc ion binding	IEP	Enrichment
MF	GO:0008324	cation transmembrane transporter activity	IEP	Enrichment
MF	GO:0008509	anion transmembrane transporter activity	IEP	Enrichment
MF	GO:0008514	organic anion transmembrane transporter activity	IEP	Enrichment
MF	GO:0008519	ammonium transmembrane transporter activity	IEP	Enrichment
BP	GO:0009063	cellular amino acid catabolic process	IEP	Enrichment
BP	GO:0009067	aspartate family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009069	serine family amino acid metabolic process	IEP	Enrichment
BP	GO:0009072	aromatic amino acid family metabolic process	IEP	Enrichment
BP	GO:0009074	aromatic amino acid family catabolic process	IEP	Enrichment
BP	GO:0009086	methionine biosynthetic process	IEP	Enrichment
BP	GO:0009092	homoserine metabolic process	IEP	Enrichment
BP	GO:0009308	amine metabolic process	IEP	Enrichment
BP	GO:0009310	amine catabolic process	IEP	Enrichment
MF	GO:0015075	ion transmembrane transporter activity	IEP	Enrichment
MF	GO:0015081	sodium ion transmembrane transporter activity	IEP	Enrichment
MF	GO:0015171	amino acid transmembrane transporter activity	IEP	Enrichment
MF	GO:0015175	neutral amino acid transmembrane transporter activity	IEP	Enrichment
MF	GO:0015291	secondary active transmembrane transporter activity	IEP	Enrichment
MF	GO:0015293	symporter activity	IEP	Enrichment
MF	GO:0015294	solute:cation symporter activity	IEP	Enrichment
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Enrichment
MF	GO:0015370	solute:sodium symporter activity	IEP	Enrichment
MF	GO:0015655	alanine:sodium symporter activity	IEP	Enrichment
BP	GO:0015696	ammonium transport	IEP	Enrichment
BP	GO:0015711	organic anion transport	IEP	Enrichment
BP	GO:0015804	neutral amino acid transport	IEP	Enrichment
BP	GO:0015849	organic acid transport	IEP	Enrichment
BP	GO:0016054	organic acid catabolic process	IEP	Enrichment
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEP	Enrichment
MF	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	IEP	Enrichment
BP	GO:0019346	transsulfuration	IEP	Enrichment
BP	GO:0019439	aromatic compound catabolic process	IEP	Enrichment
BP	GO:0019441	tryptophan catabolic process to kynurenine	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
MF	GO:0022853	active ion transmembrane transporter activity	IEP	Enrichment
MF	GO:0022858	alanine transmembrane transporter activity	IEP	Enrichment
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
BP	GO:0032328	alanine transport	IEP	Enrichment
MF	GO:0042085	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	IEP	Enrichment
BP	GO:0042180	cellular ketone metabolic process	IEP	Enrichment
BP	GO:0042402	cellular biogenic amine catabolic process	IEP	Enrichment
BP	GO:0042430	indole-containing compound metabolic process	IEP	Enrichment
BP	GO:0042436	indole-containing compound catabolic process	IEP	Enrichment
BP	GO:0042537	benzene-containing compound metabolic process	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
BP	GO:0044106	cellular amine metabolic process	IEP	Enrichment
BP	GO:0044248	cellular catabolic process	IEP	Enrichment
BP	GO:0044270	cellular nitrogen compound catabolic process	IEP	Enrichment
BP	GO:0044272	sulfur compound biosynthetic process	IEP	Enrichment
BP	GO:0044282	small molecule catabolic process	IEP	Enrichment
BP	GO:0046218	indolalkylamine catabolic process	IEP	Enrichment
BP	GO:0046395	carboxylic acid catabolic process	IEP	Enrichment
BP	GO:0046700	heterocycle catabolic process	IEP	Enrichment
MF	GO:0046873	metal ion transmembrane transporter activity	IEP	Enrichment
BP	GO:0046942	carboxylic acid transport	IEP	Enrichment
MF	GO:0046943	carboxylic acid transmembrane transporter activity	IEP	Enrichment
BP	GO:0050667	homocysteine metabolic process	IEP	Enrichment
BP	GO:0070189	kynurenine metabolic process	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment
BP	GO:0071705	nitrogen compound transport	IEP	Enrichment
BP	GO:1901361	organic cyclic compound catabolic process	IEP	Enrichment
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Enrichment
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Enrichment
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR003726	HCY_dom	13	280
IPR003171	Mehydrof_redctse-like	318	577

External Links

No external refs found!

CPC90060 (metH, ERS093114_01571)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation