CCP46506 (ponA2, Rv3682)


Aliases : ponA2, Rv3682

Description : Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insensitive transglycosylase (peptidoglycan TGASE) + penicillin-sensitive transpeptidase (DD-transpeptidase)] [Ensembl]. PASTA domain, Transglycosylase, Penicillin binding protein transpeptidase domain [Interproscan].


Gene families : OG_02_0000069 (OrthoFinder) Phylogenetic Tree(s): OG0000069_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: CCP46506
Cluster HCCA: Cluster_23

Target Alias Description ECC score Gene Family Method Actions
AAL19154 STM0190, mrcB transpeptidase of penicillin-binding protein 1b... 0.02 OrthoFinder
AGT25872 N559_4252 penicillin-binding protein 1b [Ensembl]. Penicillin... 0.02 OrthoFinder
CCG26909 No alias Multimodular transpeptidase-transglycosylase [Ensembl].... 0.02 OrthoFinder
CPD02024 mgt, ERS093114_01842 monofunctional biosynthetic peptidoglycan... 0.03 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0008658 penicillin binding IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0002161 aminoacyl-tRNA editing activity IEP Enrichment
MF GO:0003746 translation elongation factor activity IEP Enrichment
MF GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity IEP Enrichment
MF GO:0004474 malate synthase activity IEP Enrichment
MF GO:0005515 protein binding IEP Enrichment
BP GO:0006081 cellular aldehyde metabolic process IEP Enrichment
BP GO:0006082 organic acid metabolic process IEP Enrichment
BP GO:0006097 glyoxylate cycle IEP Enrichment
BP GO:0006099 tricarboxylic acid cycle IEP Enrichment
BP GO:0006399 tRNA metabolic process IEP Enrichment
BP GO:0006400 tRNA modification IEP Enrichment
BP GO:0006414 translational elongation IEP Enrichment
BP GO:0006721 terpenoid metabolic process IEP Enrichment
BP GO:0008152 metabolic process IEP Enrichment
MF GO:0008175 tRNA methyltransferase activity IEP Enrichment
MF GO:0008176 tRNA (guanine-N7-)-methyltransferase activity IEP Enrichment
MF GO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEP Enrichment
MF GO:0008924 malate dehydrogenase (quinone) activity IEP Enrichment
BP GO:0009073 aromatic amino acid family biosynthetic process IEP Enrichment
BP GO:0016114 terpenoid biosynthetic process IEP Enrichment
MF GO:0016423 tRNA (guanine) methyltransferase activity IEP Enrichment
MF GO:0016615 malate dehydrogenase activity IEP Enrichment
MF GO:0016725 oxidoreductase activity, acting on CH or CH2 groups IEP Enrichment
MF GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
MF GO:0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity IEP Enrichment
BP GO:0046487 glyoxylate metabolic process IEP Enrichment
MF GO:0046912 acyltransferase, acyl groups converted into alkyl on transfer IEP Enrichment
MF GO:0052592 oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor IEP Enrichment
MF GO:0052689 carboxylic ester hydrolase activity IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
InterPro domains Description Start Stop
IPR005543 PASTA_dom 702 761
IPR001460 PCN-bd_Tpept 364 620
IPR001264 Glyco_trans_51 70 256
UniProtKB I6YGX2