CCP46536 (leuA, Rv3710)

Aliases : leuA, Rv3710

Description : 2-isopropylmalate synthase LeuA (alpha-isopropylmalate synthase) (alpha-IPM synthetase) (IPMS) [Ensembl]. HMGL-like, LeuA allosteric (dimerisation) domain [Interproscan].

Gene families : OG_02_0002621 (OrthoFinder) Phylogenetic Tree(s): OG0002621_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCP46536
Cluster	HCCA: Cluster_41

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0003852	2-isopropylmalate synthase activity	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006551	leucine metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009098	leucine biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016746	acyltransferase activity	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
MF	GO:0046912	acyltransferase, acyl groups converted into alkyl on transfer	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001522	pseudouridine synthesis	IEP	Enrichment
MF	GO:0004175	endopeptidase activity	IEP	Enrichment
MF	GO:0004356	glutamate-ammonia ligase activity	IEP	Enrichment
CC	GO:0005576	extracellular region	IEP	Enrichment
BP	GO:0005975	carbohydrate metabolic process	IEP	Enrichment
BP	GO:0005984	disaccharide metabolic process	IEP	Enrichment
BP	GO:0005991	trehalose metabolic process	IEP	Enrichment
BP	GO:0005992	trehalose biosynthetic process	IEP	Enrichment
BP	GO:0006541	glutamine metabolic process	IEP	Enrichment
BP	GO:0006542	glutamine biosynthetic process	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
MF	GO:0008686	3,4-dihydroxy-2-butanone-4-phosphate synthase activity	IEP	Enrichment
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009311	oligosaccharide metabolic process	IEP	Enrichment
BP	GO:0009312	oligosaccharide biosynthetic process	IEP	Enrichment
MF	GO:0009982	pseudouridine synthase activity	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016211	ammonia ligase activity	IEP	Enrichment
BP	GO:0016311	dephosphorylation	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016855	racemase and epimerase activity, acting on amino acids and derivatives	IEP	Enrichment
MF	GO:0016880	acid-ammonia (or amide) ligase activity	IEP	Enrichment
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0036361	racemase activity, acting on amino acids and derivatives	IEP	Enrichment
BP	GO:0043412	macromolecule modification	IEP	Enrichment
BP	GO:0043647	inositol phosphate metabolic process	IEP	Enrichment
BP	GO:0044262	cellular carbohydrate metabolic process	IEP	Enrichment
BP	GO:0046164	alcohol catabolic process	IEP	Enrichment
BP	GO:0046174	polyol catabolic process	IEP	Enrichment
BP	GO:0046351	disaccharide biosynthetic process	IEP	Enrichment
BP	GO:0046838	phosphorylated carbohydrate dephosphorylation	IEP	Enrichment
BP	GO:0046855	inositol phosphate dephosphorylation	IEP	Enrichment
BP	GO:0071545	inositol phosphate catabolic process	IEP	Enrichment
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Enrichment
BP	GO:1901616	organic hydroxy compound catabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR000891	PYR_CT	33	312
IPR013709	2-isopropylmalate_synth_dimer	434	602

External Links

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CCP46536 (leuA, Rv3710)

Expression Profile

Co-expression Networks

Functional Annotation