CRO72766 (leuA_1)

Aliases : leuA_1

Description : 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA allosteric (dimerisation) domain [Interproscan].

Gene families : OG_02_0002621 (OrthoFinder) Phylogenetic Tree(s): OG0002621_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CRO72766
Cluster	HCCA: Cluster_38

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0003852	2-isopropylmalate synthase activity	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006551	leucine metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009098	leucine biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016746	acyltransferase activity	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
MF	GO:0046912	acyltransferase, acyl groups converted into alkyl on transfer	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEP	Enrichment
BP	GO:0001539	cilium or flagellum-dependent cell motility	IEP	Enrichment
MF	GO:0004455	ketol-acid reductoisomerase activity	IEP	Enrichment
BP	GO:0006873	cellular ion homeostasis	IEP	Enrichment
BP	GO:0006875	cellular metal ion homeostasis	IEP	Enrichment
BP	GO:0006879	cellular iron ion homeostasis	IEP	Enrichment
BP	GO:0006928	movement of cell or subcellular component	IEP	Enrichment
MF	GO:0008199	ferric iron binding	IEP	Enrichment
MF	GO:0008238	exopeptidase activity	IEP	Enrichment
BP	GO:0009081	branched-chain amino acid metabolic process	IEP	Enrichment
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016805	dipeptidase activity	IEP	Enrichment
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Enrichment
BP	GO:0019725	cellular homeostasis	IEP	Enrichment
BP	GO:0030003	cellular cation homeostasis	IEP	Enrichment
MF	GO:0030976	thiamine pyrophosphate binding	IEP	Enrichment
BP	GO:0040011	locomotion	IEP	Enrichment
BP	GO:0042592	homeostatic process	IEP	Enrichment
MF	GO:0043169	cation binding	IEP	Enrichment
CC	GO:0043190	ATP-binding cassette (ABC) transporter complex	IEP	Enrichment
MF	GO:0046872	metal ion binding	IEP	Enrichment
BP	GO:0046916	cellular transition metal ion homeostasis	IEP	Enrichment
MF	GO:0046983	protein dimerization activity	IEP	Enrichment
BP	GO:0048870	cell motility	IEP	Enrichment
BP	GO:0048878	chemical homeostasis	IEP	Enrichment
BP	GO:0050801	ion homeostasis	IEP	Enrichment
BP	GO:0055065	metal ion homeostasis	IEP	Enrichment
BP	GO:0055072	iron ion homeostasis	IEP	Enrichment
BP	GO:0055076	transition metal ion homeostasis	IEP	Enrichment
BP	GO:0055080	cation homeostasis	IEP	Enrichment
BP	GO:0055082	cellular chemical homeostasis	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
BP	GO:0065008	regulation of biological quality	IEP	Enrichment
BP	GO:0071973	bacterial-type flagellum-dependent cell motility	IEP	Enrichment
BP	GO:0097588	archaeal or bacterial-type flagellum-dependent cell motility	IEP	Enrichment
CC	GO:0098533	ATPase dependent transmembrane transport complex	IEP	Enrichment
BP	GO:0098771	inorganic ion homeostasis	IEP	Enrichment
CC	GO:0098796	membrane protein complex	IEP	Enrichment
CC	GO:0098797	plasma membrane protein complex	IEP	Enrichment
MF	GO:1901681	sulfur compound binding	IEP	Enrichment
CC	GO:1902495	transmembrane transporter complex	IEP	Enrichment
CC	GO:1904949	ATPase complex	IEP	Enrichment
CC	GO:1990351	transporter complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR000891	PYR_CT	33	313
IPR013709	2-isopropylmalate_synth_dimer	422	547

External Links

Locus_tag	PAERUG_E11_London_26_VIM_2_06_13_03272

CRO72766 (leuA_1)

Expression Profile

Co-expression Networks

Functional Annotation