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Aliases : pflA, b0902
Description : pyruvate formate-lyase 1-activating enzyme; [formate-C-acetyltransferase 1]-activating enzyme; PFL activase [Ensembl]. Radical SAM superfamily, 4Fe-4S single cluster domain [Interproscan].
Gene families : OG_02_0000132 (OrthoFinder) Phylogenetic Tree(s): OG0000132_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: AAC73988 | |
| Cluster | HCCA: Cluster_2 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AAL19904 | STM0970, pflA | pyruvate formate lyase activating enzyme 1 [Ensembl].... | 0.08 | OrthoFinder | |
| AEA94015 | pflA, OG1RF_11328 | pyruvate formate-lyase activating enzyme [Ensembl].... | 0.02 | OrthoFinder | |
| AGT25004 | N559_3348 | pyruvate formate lyase-activating enzyme 1 [Ensembl].... | 0.03 | OrthoFinder | |
| EDJ90583 | pflA, CGSHi22421_01222 | pyruvate formate lyase-activating enzyme 1 [Ensembl].... | 0.03 | OrthoFinder |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0003824 | catalytic activity | IEA | Interproscan |
| MF | GO:0051536 | iron-sulfur cluster binding | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0003712 | transcription coregulator activity | IEP | Enrichment |
| MF | GO:0003714 | transcription corepressor activity | IEP | Enrichment |
| MF | GO:0003941 | L-serine ammonia-lyase activity | IEP | Enrichment |
| BP | GO:0006006 | glucose metabolic process | IEP | Enrichment |
| BP | GO:0006094 | gluconeogenesis | IEP | Enrichment |
| BP | GO:0009060 | aerobic respiration | IEP | Enrichment |
| BP | GO:0015980 | energy derivation by oxidation of organic compounds | IEP | Enrichment |
| MF | GO:0016742 | hydroxymethyl-, formyl- and related transferase activity | IEP | Enrichment |
| MF | GO:0016840 | carbon-nitrogen lyase activity | IEP | Enrichment |
| MF | GO:0016841 | ammonia-lyase activity | IEP | Enrichment |
| MF | GO:0016989 | sigma factor antagonist activity | IEP | Enrichment |
| BP | GO:0019319 | hexose biosynthetic process | IEP | Enrichment |
| BP | GO:0019646 | aerobic electron transport chain | IEP | Enrichment |
| BP | GO:0022900 | electron transport chain | IEP | Enrichment |
| BP | GO:0022904 | respiratory electron transport chain | IEP | Enrichment |
| BP | GO:0045333 | cellular respiration | IEP | Enrichment |
| BP | GO:0046364 | monosaccharide biosynthetic process | IEP | Enrichment |
| CC | GO:0070069 | cytochrome complex | IEP | Enrichment |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR007197 | rSAM | 24 | 178 |
| UniProtKB | P0A9N4 |