AAC75087 (hisI, b2026)


Aliases : hisI, b2026

Description : phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase [Ensembl]. Phosphoribosyl-AMP cyclohydrolase, Phosphoribosyl-ATP pyrophosphohydrolase [Interproscan].


Gene families : OG_02_0000827 (OrthoFinder) Phylogenetic Tree(s): OG0000827_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AAC75087
Cluster HCCA: Cluster_32

Target Alias Description ECC score Gene Family Method Actions
AAL20982 STM2078, hisI phosphoribosyl-AMP cyclohydrolase [Ensembl].... 0.16 OrthoFinder
AGT23511 N559_1775 bifunctional phosphoribosyl-AMP... 0.09 OrthoFinder
AHY40777 CJ8421_08025 bifunctional phosphoribosyl-AMP... 0.04 OrthoFinder
AKI48511 hisI, L2625_00575 phosphoribosyl-AMP cyclohydrolase [Ensembl].... 0.06 OrthoFinder
CCL17756 hisI, BN171_1760001 Histidine biosynthesis bifunctional protein HisIE... 0.09 OrthoFinder
CCP44370 hisI, Rv1606 Probable phosphoribosyl-AMP 1,6 cyclohydrolase HisI... 0.07 OrthoFinder
CPC67916 hisI, ERS093114_01038 Phosphoribosyl-AMP cyclohydrolase / Phosphoribosyl-ATP... 0.25 OrthoFinder
EDJ91517 atpC, CGSHi22421_07097 F0F1 ATP synthase subunit epsilon [Ensembl].... 0.12 OrthoFinder
KNA53867 VCV51_030805 phosphoribosyl-ATP pyrophosphohydrolase [Ensembl].... 0.12 OrthoFinder

Type GO Term Name Evidence Source
BP GO:0000105 histidine biosynthetic process IEA Interproscan
MF GO:0004635 phosphoribosyl-AMP cyclohydrolase activity IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEP Enrichment
MF GO:0003879 ATP phosphoribosyltransferase activity IEP Enrichment
MF GO:0004399 histidinol dehydrogenase activity IEP Enrichment
MF GO:0004424 imidazoleglycerol-phosphate dehydratase activity IEP Enrichment
BP GO:0006553 lysine metabolic process IEP Enrichment
MF GO:0008839 4-hydroxy-tetrahydrodipicolinate reductase IEP Enrichment
BP GO:0009066 aspartate family amino acid metabolic process IEP Enrichment
BP GO:0009067 aspartate family amino acid biosynthetic process IEP Enrichment
BP GO:0009085 lysine biosynthetic process IEP Enrichment
BP GO:0009089 lysine biosynthetic process via diaminopimelate IEP Enrichment
MF GO:0016491 oxidoreductase activity IEP Enrichment
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Enrichment
MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEP Enrichment
MF GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor IEP Enrichment
MF GO:0016763 pentosyltransferase activity IEP Enrichment
MF GO:0016835 carbon-oxygen lyase activity IEP Enrichment
MF GO:0016836 hydro-lyase activity IEP Enrichment
MF GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043169 cation binding IEP Enrichment
BP GO:0043648 dicarboxylic acid metabolic process IEP Enrichment
BP GO:0046451 diaminopimelate metabolic process IEP Enrichment
MF GO:0046872 metal ion binding IEP Enrichment
MF GO:0046983 protein dimerization activity IEP Enrichment
MF GO:0051287 NAD binding IEP Enrichment
BP GO:0055114 obsolete oxidation-reduction process IEP Enrichment
BP GO:1901607 alpha-amino acid biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR021130 PRib-ATP_PPHydrolase-like 116 202
IPR002496 PRib_AMP_CycHydrolase_dom 33 105
UniProtKB P06989