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GO:0045047: protein targeting to ER (Biological process)

"The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane." [ISBN:0716731363]


There are 874 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_44 Klebsiella pneumoniae 1.49 % 0.000674 0.00353
Cluster_5 Mycoplasma pneumoniae 2.78 % 0.012941 0.037883
Cluster_32 Salmonella enterica 1.14 % 0.001469 0.026353
Cluster_5 Staphylococcus aureus 1.08 % 0.004893 0.021554
Sequences (874) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms