Coexpression cluster: Cluster_5 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0017076 purine nucleotide binding 18.92% (35/185) 1.59 0.0 0.0
GO:0035639 purine ribonucleoside triphosphate binding 18.92% (35/185) 1.6 0.0 0.0
GO:0032555 purine ribonucleotide binding 18.92% (35/185) 1.6 0.0 0.0
GO:0032553 ribonucleotide binding 18.92% (35/185) 1.55 0.0 0.0
GO:1901363 heterocyclic compound binding 29.73% (55/185) 1.12 0.0 0.0
GO:0097159 organic cyclic compound binding 29.73% (55/185) 1.12 0.0 0.0
GO:0097367 carbohydrate derivative binding 18.92% (35/185) 1.5 0.0 0.0
GO:0000166 nucleotide binding 19.46% (36/185) 1.39 0.0 1e-06
GO:1901265 nucleoside phosphate binding 19.46% (36/185) 1.39 0.0 1e-06
GO:0090304 nucleic acid metabolic process 13.51% (25/185) 1.78 0.0 1e-06
GO:0003676 nucleic acid binding 17.84% (33/185) 1.48 0.0 1e-06
GO:0005488 binding 31.89% (59/185) 0.95 0.0 2e-06
GO:0043168 anion binding 19.46% (36/185) 1.32 0.0 2e-06
GO:0006139 nucleobase-containing compound metabolic process 15.68% (29/185) 1.47 0.0 5e-06
GO:0036094 small molecule binding 19.46% (36/185) 1.16 2e-06 3.7e-05
GO:0019001 guanyl nucleotide binding 4.86% (9/185) 2.68 3e-06 6e-05
GO:0032561 guanyl ribonucleotide binding 4.86% (9/185) 2.68 3e-06 6e-05
GO:0005525 GTP binding 4.86% (9/185) 2.68 3e-06 6e-05
GO:0006725 cellular aromatic compound metabolic process 15.68% (29/185) 1.27 4e-06 7.1e-05
GO:0032559 adenyl ribonucleotide binding 14.05% (26/185) 1.35 4e-06 7.5e-05
GO:0005524 ATP binding 14.05% (26/185) 1.35 4e-06 7.5e-05
GO:0030554 adenyl nucleotide binding 14.05% (26/185) 1.34 5e-06 8.2e-05
GO:0046483 heterocycle metabolic process 15.68% (29/185) 1.23 7e-06 0.000102
GO:0043167 ion binding 19.46% (36/185) 1.07 6e-06 0.000103
GO:0016070 RNA metabolic process 7.57% (14/185) 1.94 7e-06 0.000105
GO:1901360 organic cyclic compound metabolic process 15.68% (29/185) 1.2 1e-05 0.000149
GO:0003674 molecular_function 53.51% (99/185) 0.48 1.2e-05 0.00016
GO:0008168 methyltransferase activity 4.86% (9/185) 2.48 1.2e-05 0.00016
GO:0043170 macromolecule metabolic process 16.76% (31/185) 1.12 1.6e-05 0.000199
GO:0016741 transferase activity, transferring one-carbon groups 5.41% (10/185) 2.2 2.7e-05 0.000338
GO:0003824 catalytic activity 35.14% (65/185) 0.63 4.7e-05 0.000563
GO:0003723 RNA binding 5.95% (11/185) 1.94 7.4e-05 0.000852
GO:0140098 catalytic activity, acting on RNA 5.41% (10/185) 2.03 8.8e-05 0.000992
GO:0140097 catalytic activity, acting on DNA 4.86% (9/185) 1.96 0.000298 0.003245
GO:0006281 DNA repair 3.78% (7/185) 2.25 0.000372 0.003627
GO:0006974 cellular response to DNA damage stimulus 3.78% (7/185) 2.25 0.000372 0.003627
GO:0033554 cellular response to stress 3.78% (7/185) 2.25 0.000372 0.003627
GO:0044238 primary metabolic process 20.54% (38/185) 0.78 0.000355 0.003757
GO:0034641 cellular nitrogen compound metabolic process 15.68% (29/185) 0.91 0.000459 0.00435
GO:0051716 cellular response to stimulus 3.78% (7/185) 2.18 0.000514 0.004757
GO:0016740 transferase activity 14.05% (26/185) 0.96 0.000563 0.005082
GO:0006259 DNA metabolic process 5.95% (11/185) 1.59 0.000711 0.006118
GO:0006418 tRNA aminoacylation for protein translation 3.24% (6/185) 2.33 0.000707 0.006229
GO:0043038 amino acid activation 3.24% (6/185) 2.25 0.000999 0.007547
GO:0016875 ligase activity, forming carbon-oxygen bonds 3.24% (6/185) 2.25 0.000999 0.007547
GO:0004812 aminoacyl-tRNA ligase activity 3.24% (6/185) 2.25 0.000999 0.007547
GO:0043039 tRNA aminoacylation 3.24% (6/185) 2.25 0.000999 0.007547
GO:0016874 ligase activity 4.86% (9/185) 1.76 0.000927 0.00762
GO:0006950 response to stress 3.78% (7/185) 2.06 0.000925 0.00778
GO:0044237 cellular metabolic process 20.54% (38/185) 0.7 0.001094 0.008096
GO:0008094 ATPase, acting on DNA 2.16% (4/185) 2.83 0.001311 0.008819
GO:0030983 mismatched DNA binding 1.62% (3/185) 3.42 0.001288 0.008828
GO:0006298 mismatch repair 1.62% (3/185) 3.42 0.001288 0.008828
GO:0003690 double-stranded DNA binding 1.62% (3/185) 3.42 0.001288 0.008828
GO:0034660 ncRNA metabolic process 4.32% (8/185) 1.83 0.001225 0.008888
GO:0140101 catalytic activity, acting on a tRNA 3.78% (7/185) 1.94 0.001559 0.010301
GO:0008152 metabolic process 24.32% (45/185) 0.59 0.00198 0.012855
GO:0071704 organic substance metabolic process 22.16% (41/185) 0.62 0.002091 0.013341
GO:0016866 intramolecular transferase activity 2.16% (4/185) 2.66 0.002231 0.013992
GO:0050896 response to stimulus 3.78% (7/185) 1.78 0.00309 0.018438
GO:0008173 RNA methyltransferase activity 1.62% (3/185) 3.1 0.003055 0.018529
GO:0004386 helicase activity 1.62% (3/185) 3.1 0.003055 0.018529
GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.08% (2/185) 3.83 0.004893 0.021554
GO:0004529 exodeoxyribonuclease activity 1.08% (2/185) 3.83 0.004893 0.021554
GO:0004536 deoxyribonuclease activity 1.08% (2/185) 3.83 0.004893 0.021554
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 1.08% (2/185) 3.83 0.004893 0.021554
GO:0008855 exodeoxyribonuclease VII activity 1.08% (2/185) 3.83 0.004893 0.021554
GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters 1.08% (2/185) 3.83 0.004893 0.021554
GO:0090150 establishment of protein localization to membrane 1.08% (2/185) 3.83 0.004893 0.021554
GO:0072657 protein localization to membrane 1.08% (2/185) 3.83 0.004893 0.021554
GO:0006613 cotranslational protein targeting to membrane 1.08% (2/185) 3.83 0.004893 0.021554
GO:0009378 four-way junction helicase activity 1.08% (2/185) 3.83 0.004893 0.021554
GO:0033365 protein localization to organelle 1.08% (2/185) 3.83 0.004893 0.021554
GO:0034613 cellular protein localization 1.08% (2/185) 3.83 0.004893 0.021554
GO:0045047 protein targeting to ER 1.08% (2/185) 3.83 0.004893 0.021554
GO:0004826 phenylalanine-tRNA ligase activity 1.08% (2/185) 3.83 0.004893 0.021554
GO:0006432 phenylalanyl-tRNA aminoacylation 1.08% (2/185) 3.83 0.004893 0.021554
GO:0070727 cellular macromolecule localization 1.08% (2/185) 3.83 0.004893 0.021554
GO:0051668 localization within membrane 1.08% (2/185) 3.83 0.004893 0.021554
GO:0006612 protein targeting to membrane 1.08% (2/185) 3.83 0.004893 0.021554
GO:0072599 establishment of protein localization to endoplasmic reticulum 1.08% (2/185) 3.83 0.004893 0.021554
GO:0072594 establishment of protein localization to organelle 1.08% (2/185) 3.83 0.004893 0.021554
GO:0070972 protein localization to endoplasmic reticulum 1.08% (2/185) 3.83 0.004893 0.021554
GO:0043412 macromolecule modification 3.24% (6/185) 1.83 0.005083 0.022127
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.16% (4/185) 2.37 0.005226 0.022226
GO:0016817 hydrolase activity, acting on acid anhydrides 2.16% (4/185) 2.37 0.005226 0.022226
GO:0009982 pseudouridine synthase activity 1.62% (3/185) 2.83 0.005795 0.024093
GO:0001522 pseudouridine synthesis 1.62% (3/185) 2.83 0.005795 0.024093
GO:0003677 DNA binding 8.11% (15/185) 1.01 0.00608 0.024996
GO:0006807 nitrogen compound metabolic process 17.84% (33/185) 0.65 0.004257 0.024999
GO:0006399 tRNA metabolic process 3.24% (6/185) 1.72 0.00773 0.031431
GO:0003924 GTPase activity 1.62% (3/185) 2.61 0.009622 0.037873
GO:0051276 chromosome organization 1.62% (3/185) 2.61 0.009622 0.037873
GO:0017111 nucleoside-triphosphatase activity 1.62% (3/185) 2.61 0.009622 0.037873
GO:0006396 RNA processing 2.7% (5/185) 1.83 0.01047 0.040778
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Campylobacter jejuni HCCA Cluster_1 0.048 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_7 0.048 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_8 0.031 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_2 0.051 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_19 0.034 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_30 0.061 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_35 0.03 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_37 0.03 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_2 0.042 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_7 0.064 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_10 0.033 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_13 0.047 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_17 0.049 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_21 0.035 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_28 0.05 OrthoFinder Compare
Escherichia coli HCCA Cluster_2 0.031 OrthoFinder Compare
Escherichia coli HCCA Cluster_29 0.059 OrthoFinder Compare
Escherichia coli HCCA Cluster_39 0.035 OrthoFinder Compare
Escherichia coli HCCA Cluster_40 0.035 OrthoFinder Compare
Escherichia coli HCCA Cluster_41 0.051 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_3 0.04 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_7 0.043 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_14 0.029 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_22 0.031 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_1 0.032 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_10 0.033 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_14 0.042 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_26 0.067 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_29 0.031 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_44 0.069 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_2 0.031 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_18 0.077 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_20 0.042 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_24 0.107 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_28 0.04 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_1 0.03 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_5 0.029 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_28 0.038 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_1 0.028 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_7 0.031 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_8 0.041 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_12 0.057 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_17 0.028 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_34 0.054 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_35 0.036 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_40 0.05 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_51 0.048 OrthoFinder Compare
Salmonella enterica HCCA Cluster_3 0.051 OrthoFinder Compare
Salmonella enterica HCCA Cluster_31 0.061 OrthoFinder Compare
Salmonella enterica HCCA Cluster_32 0.036 OrthoFinder Compare
Salmonella enterica HCCA Cluster_42 0.029 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_2 0.047 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_3 0.036 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_14 0.069 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_16 0.047 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_18 0.082 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_19 0.035 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_1 0.029 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_4 0.04 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_5 0.04 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_7 0.06 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_11 0.085 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_16 0.036 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_17 0.044 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_18 0.03 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_1 0.048 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_24 0.08 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_32 0.041 OrthoFinder Compare
Sequences (185) (download table)

InterPro Domains

GO Terms

Family Terms