EDJ91313 (CGSHi22421_04398)

Aliases : CGSHi22421_04398

Description : DNA polymerase III subunit alpha [Ensembl]. PHP domain, Helix-hairpin-helix motif, OB-fold nucleic acid binding domain, Bacterial DNA polymerase III alpha NTPase domain, Bacterial DNA polymerase III alpha subunit finger domain [Interproscan].

Gene families : OG_02_0000325 (OrthoFinder) Phylogenetic Tree(s): OG0000325_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: EDJ91313
Cluster	HCCA: Cluster_22

Target	Alias	Description	ECC score	Gene Family Method
AKP15394	dnaE, WX61_01347	DNA polymerase III subunit alpha [Ensembl]. PHP domain,...	0.03	OrthoFinder
CCG26417	No alias	DNA polymerase III alpha subunit [Ensembl]. PHP domain,...	0.03	OrthoFinder
CRO13404	dnaE	DNA polymerase III subunit alpha [Ensembl]. PHP domain,...	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008408	3'-5' exonuclease activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000105	histidine biosynthetic process	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006547	histidine metabolic process	IEP	Enrichment
BP	GO:0008104	protein localization	IEP	Enrichment
MF	GO:0008312	7S RNA binding	IEP	Enrichment
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Enrichment
MF	GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	IEP	Enrichment
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Enrichment
BP	GO:0009892	negative regulation of metabolic process	IEP	Enrichment
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Enrichment
BP	GO:0015031	protein transport	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Enrichment
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Enrichment
BP	GO:0031554	regulation of DNA-templated transcription, termination	IEP	Enrichment
BP	GO:0033036	macromolecule localization	IEP	Enrichment
BP	GO:0043242	negative regulation of protein-containing complex disassembly	IEP	Enrichment
BP	GO:0043244	regulation of protein-containing complex disassembly	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0045184	establishment of protein localization	IEP	Enrichment
BP	GO:0045892	negative regulation of transcription, DNA-templated	IEP	Enrichment
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Enrichment
CC	GO:0048500	signal recognition particle	IEP	Enrichment
BP	GO:0048519	negative regulation of biological process	IEP	Enrichment
BP	GO:0048523	negative regulation of cellular process	IEP	Enrichment
BP	GO:0051128	regulation of cellular component organization	IEP	Enrichment
BP	GO:0051129	negative regulation of cellular component organization	IEP	Enrichment
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0051253	negative regulation of RNA metabolic process	IEP	Enrichment
BP	GO:0060567	negative regulation of DNA-templated transcription, termination	IEP	Enrichment
BP	GO:1902679	negative regulation of RNA biosynthetic process	IEP	Enrichment
BP	GO:1903507	negative regulation of nucleic acid-templated transcription	IEP	Enrichment
CC	GO:1990904	ribonucleoprotein complex	IEP	Enrichment
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR011708	DNA_pol3_alpha_NTPase_dom	292	558
IPR029460	DNAPol_HHH	808	897
IPR004013	PHP_dom	9	171
IPR040982	DNA_pol3_finger	561	735
IPR004365	NA-bd_OB_tRNA	994	1069

External Links

No external refs found!

EDJ91313 (CGSHi22421_04398)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation