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  5. AKI49271

AKI49271 (topA, L2625_01365)


Aliases : topA, L2625_01365

Description : DNA topoisomerase I [Ensembl]. TOPRIM domain, DNA topoisomerase [Interproscan].


Gene families : OG_02_0000393 (OrthoFinder) Phylogenetic Tree(s): OG0000393_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AKI49271
Cluster HCCA: Cluster_4

Target Alias Description ECC score Gene Family Method Actions
AGT24669 N559_3006 DNA topoisomerase I [Ensembl]. Toprim domain [InterProScan]. 0.03 OrthoFinder
AKP15097 topA, WX61_01039 DNA topoisomerase 1 [Ensembl]. Toprim domain, DNA... 0.02 OrthoFinder
CBI67006 topA5, HPB8_1449 DNA topoisomerase I [Ensembl]. Toprim domain, DNA... 0.02 OrthoFinder
CCG27509 No alias DNA topoisomerase I [Ensembl]. Toprim domain, DNA... 0.04 OrthoFinder
CCL17440 topA, BN171_1500016 DNA topoisomerase I [Ensembl]. DNA topoisomerase, Toprim... 0.04 OrthoFinder
CPC35500 topA, ERS093114_00174 DNA topoisomerase I [Ensembl]. Toprim domain, DNA... 0.03 OrthoFinder
CRO91125 topA_2 DNA topoisomerase 1 [Ensembl]. Toprim domain, DNA... 0.03 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA Interproscan
MF GO:0003916 DNA topoisomerase activity IEA Interproscan
CC GO:0005694 chromosome IEA Interproscan
BP GO:0006265 DNA topological change IEA Interproscan
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Enrichment
BP GO:0000413 protein peptidyl-prolyl isomerization IEP Enrichment
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEP Enrichment
MF GO:0004345 glucose-6-phosphate dehydrogenase activity IEP Enrichment
MF GO:0005525 GTP binding IEP Enrichment
BP GO:0006281 DNA repair IEP Enrichment
BP GO:0006282 regulation of DNA repair IEP Enrichment
BP GO:0006457 protein folding IEP Enrichment
BP GO:0006464 cellular protein modification process IEP Enrichment
BP GO:0006974 cellular response to DNA damage stimulus IEP Enrichment
MF GO:0008144 drug binding IEP Enrichment
MF GO:0008658 penicillin binding IEP Enrichment
MF GO:0008725 DNA-3-methyladenine glycosylase activity IEP Enrichment
BP GO:0010035 response to inorganic substance IEP Enrichment
BP GO:0010038 response to metal ion IEP Enrichment
MF GO:0016859 cis-trans isomerase activity IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
BP GO:0018193 peptidyl-amino acid modification IEP Enrichment
BP GO:0018208 peptidyl-proline modification IEP Enrichment
MF GO:0019001 guanyl nucleotide binding IEP Enrichment
MF GO:0030151 molybdenum ion binding IEP Enrichment
MF GO:0031406 carboxylic acid binding IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032561 guanyl ribonucleotide binding IEP Enrichment
MF GO:0033218 amide binding IEP Enrichment
MF GO:0033293 monocarboxylic acid binding IEP Enrichment
BP GO:0033554 cellular response to stress IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
BP GO:0036211 protein modification process IEP Enrichment
CC GO:0042597 periplasmic space IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
MF GO:0043177 organic acid binding IEP Enrichment
MF GO:0043733 DNA-3-methylbase glycosylase activity IEP Enrichment
BP GO:0046688 response to copper ion IEP Enrichment
BP GO:0048583 regulation of response to stimulus IEP Enrichment
BP GO:0050896 response to stimulus IEP Enrichment
BP GO:0051052 regulation of DNA metabolic process IEP Enrichment
BP GO:0080134 regulation of response to stress IEP Enrichment
BP GO:0080135 regulation of cellular response to stress IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:2001020 regulation of response to DNA damage stimulus IEP Enrichment
InterPro domains Description Start Stop
IPR006171 TOPRIM_domain 5 113
IPR013498 Topo_IA_Znf 617 655
IPR013498 Topo_IA_Znf 658 691
IPR013498 Topo_IA_Znf 577 612
IPR013497 Topo_IA_cen 127 548
No external refs found!