AKI49674 (L2625_01789)


Aliases : L2625_01789

Description : bifunctional homocysteine S-methyltransferase family/methylenetetrahydrofolate reductase family protein [Ensembl]. Homocysteine-binding domain, Methylenetetrahydrofolate reductase [Interproscan].


Gene families : OG_02_0000961 (OrthoFinder) Phylogenetic Tree(s): OG0000961_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AKI49674
Cluster HCCA: Cluster_15

Target Alias Description ECC score Gene Family Method Actions
AAC73364 mmuM, b0261 CP4-6 prophage; S-methylmethionine:homocysteine... 0.04 OrthoFinder
AAL23012 STM4188, metH B12-dependent homocysteine-N5-methyltetrahydrofolate... 0.06 OrthoFinder
AGT25728 N559_4102 homocysteine methyltransferase [Ensembl].... 0.05 OrthoFinder
CPC90060 metH, ERS093114_01571 5%2C10-methylenetetrahydrofolate reductase-like... 0.05 OrthoFinder
CRO36716 metH Methionine synthase [Ensembl]. B12 binding domain,... 0.03 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity IEA Interproscan
BP GO:0006555 methionine metabolic process IEA Interproscan
BP GO:0055114 obsolete oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source
BP GO:0000097 sulfur amino acid biosynthetic process IEP Enrichment
MF GO:0003852 2-isopropylmalate synthase activity IEP Enrichment
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Enrichment
MF GO:0004424 imidazoleglycerol-phosphate dehydratase activity IEP Enrichment
MF GO:0004425 indole-3-glycerol-phosphate synthase activity IEP Enrichment
MF GO:0004455 ketol-acid reductoisomerase activity IEP Enrichment
MF GO:0004640 phosphoribosylanthranilate isomerase activity IEP Enrichment
BP GO:0006534 cysteine metabolic process IEP Enrichment
BP GO:0006536 glutamate metabolic process IEP Enrichment
BP GO:0006537 glutamate biosynthetic process IEP Enrichment
BP GO:0006551 leucine metabolic process IEP Enrichment
BP GO:0006568 tryptophan metabolic process IEP Enrichment
BP GO:0006586 indolalkylamine metabolic process IEP Enrichment
MF GO:0008172 S-methyltransferase activity IEP Enrichment
MF GO:0008270 zinc ion binding IEP Enrichment
BP GO:0008652 cellular amino acid biosynthetic process IEP Enrichment
BP GO:0009067 aspartate family amino acid biosynthetic process IEP Enrichment
BP GO:0009069 serine family amino acid metabolic process IEP Enrichment
BP GO:0009081 branched-chain amino acid metabolic process IEP Enrichment
BP GO:0009082 branched-chain amino acid biosynthetic process IEP Enrichment
BP GO:0009086 methionine biosynthetic process IEP Enrichment
BP GO:0009092 homoserine metabolic process IEP Enrichment
BP GO:0009098 leucine biosynthetic process IEP Enrichment
MF GO:0015035 protein-disulfide reductase activity IEP Enrichment
MF GO:0015036 disulfide oxidoreductase activity IEP Enrichment
MF GO:0015930 glutamate synthase activity IEP Enrichment
BP GO:0016053 organic acid biosynthetic process IEP Enrichment
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Enrichment
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Enrichment
MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEP Enrichment
MF GO:0016829 lyase activity IEP Enrichment
MF GO:0016830 carbon-carbon lyase activity IEP Enrichment
BP GO:0019346 transsulfuration IEP Enrichment
MF GO:0019842 vitamin binding IEP Enrichment
MF GO:0030170 pyridoxal phosphate binding IEP Enrichment
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Enrichment
BP GO:0042430 indole-containing compound metabolic process IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043169 cation binding IEP Enrichment
BP GO:0043650 dicarboxylic acid biosynthetic process IEP Enrichment
BP GO:0044272 sulfur compound biosynthetic process IEP Enrichment
BP GO:0044283 small molecule biosynthetic process IEP Enrichment
BP GO:0046394 carboxylic acid biosynthetic process IEP Enrichment
MF GO:0046872 metal ion binding IEP Enrichment
MF GO:0046914 transition metal ion binding IEP Enrichment
BP GO:0050667 homocysteine metabolic process IEP Enrichment
MF GO:0070279 vitamin B6 binding IEP Enrichment
BP GO:1901566 organonitrogen compound biosynthetic process IEP Enrichment
BP GO:1901607 alpha-amino acid biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR003726 HCY_dom 12 283
IPR003171 Mehydrof_redctse-like 321 583
No external refs found!