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GO:0016829: lyase activity (Molecular function)

"Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." [ISBN:0198547684]


There are 2615 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_5 Haemophilus influenzae 5.43 % 0.00141 0.030591
Cluster_30 Klebsiella pneumoniae 5.33 % 0.000855 0.014878
Cluster_63 Klebsiella pneumoniae 40.0 % 0.002151 0.006639
Cluster_9 Listeria monocytogenes 8.11 % 0.000326 0.003074
Cluster_68 Salmonella enterica 100.0 % 0.000282 0.001411
Cluster_22 Salmonella enterica 9.46 % 0.000218 0.004136
Sequences (2615) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms