AKI49677 (metE, L2625_01792)

Aliases : metE, L2625_01792

Description : 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase [Ensembl]. Cobalamin-independent methionine synthase MetE [Interproscan].

Gene families : OG_02_0000815 (OrthoFinder) Phylogenetic Tree(s): OG0000815_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI49677
Cluster	HCCA: Cluster_15

Target	Alias	Description	ECC score	Gene Family Method
AAC76832	metE, b3829	5-methyltetrahydropteroyltriglutamate-homocysteine...	0.06	OrthoFinder
AAL22809	STM3965, metE	5-methyltetrahydropteroyltriglutamate-homocysteine...	0.05	OrthoFinder
AGT23847	N559_2131	5-methyltetrahydropteroyltriglutamate-homocysteine...	0.04	OrthoFinder
AKP16035	metE, WX61_02008	5-methyltetrahydropteroyltriglutamate--homocysteine...	0.03	OrthoFinder
CPC90093	metE, ERS093114_01572	5-methyltetrahydropteroyltriglutamate--homocysteine...	0.1	OrthoFinder
CRN86909	metE	5-methyltetrahydropteroyltriglutamate--homocysteine...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	None	Extended
BP	GO:0000097	sulfur amino acid biosynthetic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003871	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006555	methionine metabolic process	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	None	Extended
MF	GO:0008172	S-methyltransferase activity	None	Extended
MF	GO:0008270	zinc ion binding	IEA	Interproscan
BP	GO:0008652	cellular amino acid biosynthetic process	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009066	aspartate family amino acid metabolic process	None	Extended
BP	GO:0009067	aspartate family amino acid biosynthetic process	None	Extended
BP	GO:0009086	methionine biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0042085	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044272	sulfur compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended
BP	GO:1901607	alpha-amino acid biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003852	2-isopropylmalate synthase activity	IEP	Enrichment
MF	GO:0004107	chorismate synthase activity	IEP	Enrichment
MF	GO:0004425	indole-3-glycerol-phosphate synthase activity	IEP	Enrichment
MF	GO:0004455	ketol-acid reductoisomerase activity	IEP	Enrichment
MF	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity	IEP	Enrichment
MF	GO:0004640	phosphoribosylanthranilate isomerase activity	IEP	Enrichment
BP	GO:0006534	cysteine metabolic process	IEP	Enrichment
BP	GO:0006536	glutamate metabolic process	IEP	Enrichment
BP	GO:0006537	glutamate biosynthetic process	IEP	Enrichment
BP	GO:0006551	leucine metabolic process	IEP	Enrichment
BP	GO:0006568	tryptophan metabolic process	IEP	Enrichment
BP	GO:0006586	indolalkylamine metabolic process	IEP	Enrichment
MF	GO:0008080	N-acetyltransferase activity	IEP	Enrichment
BP	GO:0009069	serine family amino acid metabolic process	IEP	Enrichment
BP	GO:0009072	aromatic amino acid family metabolic process	IEP	Enrichment
BP	GO:0009081	branched-chain amino acid metabolic process	IEP	Enrichment
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009092	homoserine metabolic process	IEP	Enrichment
BP	GO:0009098	leucine biosynthetic process	IEP	Enrichment
MF	GO:0015930	glutamate synthase activity	IEP	Enrichment
MF	GO:0016407	acetyltransferase activity	IEP	Enrichment
MF	GO:0016410	N-acyltransferase activity	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEP	Enrichment
MF	GO:0016746	acyltransferase activity	IEP	Enrichment
MF	GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016830	carbon-carbon lyase activity	IEP	Enrichment
MF	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	IEP	Enrichment
BP	GO:0019346	transsulfuration	IEP	Enrichment
MF	GO:0019842	vitamin binding	IEP	Enrichment
MF	GO:0030170	pyridoxal phosphate binding	IEP	Enrichment
BP	GO:0042430	indole-containing compound metabolic process	IEP	Enrichment
BP	GO:0043650	dicarboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0050667	homocysteine metabolic process	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
MF	GO:0070279	vitamin B6 binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002629	Met_Synth_C/arc	443	765
IPR013215	Cbl-indep_Met_Synth_N	17	325

External Links

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AKI49677 (metE, L2625_01792)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation