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  5. AKI49982

AKI49982 (leuA, L2625_02135)


Aliases : leuA, L2625_02135

Description : 2-isopropylmalate synthase [Ensembl]. Pyruvate carboxyltransferase, 2-isopropylmalate synthase LeuA [Interproscan].


Gene families : OG_02_0000655 (OrthoFinder) Phylogenetic Tree(s): OG0000655_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AKI49982
Cluster HCCA: Cluster_6

Target Alias Description ECC score Gene Family Method Actions
AAC73185 leuA, b0074 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA... 0.04 OrthoFinder
AAL19077 STM0113, leuA 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA... 0.09 OrthoFinder
AGT25961 N559_4351 2-isopropylmalate synthase [Ensembl]. LeuA allosteric... 0.13 OrthoFinder
AHY40904 CJ8421_08660 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA... 0.02 OrthoFinder
CCL17001 aksA, BN171_1070003 Trans-homoaconitate synthase [Ensembl]. HMGL-like [Interproscan]. 0.05 OrthoFinder
CPD08084 leuA_2, ERS093114_02010 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA... 0.12 OrthoFinder
KNA51159 VCV51_031676 2-isopropylmalate synthase [Ensembl]. HMGL-like, LeuA... 0.07 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0003852 2-isopropylmalate synthase activity IEA Interproscan
BP GO:0009098 leucine biosynthetic process IEA Interproscan
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Type GO Term Name Evidence Source
BP GO:0000096 sulfur amino acid metabolic process IEP Enrichment
BP GO:0000097 sulfur amino acid biosynthetic process IEP Enrichment
BP GO:0000105 histidine biosynthetic process IEP Enrichment
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Enrichment
MF GO:0003879 ATP phosphoribosyltransferase activity IEP Enrichment
MF GO:0004356 glutamate-ammonia ligase activity IEP Enrichment
MF GO:0004399 histidinol dehydrogenase activity IEP Enrichment
MF GO:0004424 imidazoleglycerol-phosphate dehydratase activity IEP Enrichment
MF GO:0004455 ketol-acid reductoisomerase activity IEP Enrichment
MF GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity IEP Enrichment
BP GO:0006536 glutamate metabolic process IEP Enrichment
BP GO:0006537 glutamate biosynthetic process IEP Enrichment
BP GO:0006541 glutamine metabolic process IEP Enrichment
BP GO:0006542 glutamine biosynthetic process IEP Enrichment
BP GO:0006547 histidine metabolic process IEP Enrichment
BP GO:0006555 methionine metabolic process IEP Enrichment
BP GO:0006790 sulfur compound metabolic process IEP Enrichment
BP GO:0006808 regulation of nitrogen utilization IEP Enrichment
BP GO:0006811 ion transport IEP Enrichment
BP GO:0006812 cation transport IEP Enrichment
MF GO:0008172 S-methyltransferase activity IEP Enrichment
MF GO:0008324 cation transmembrane transporter activity IEP Enrichment
MF GO:0008519 ammonium transmembrane transporter activity IEP Enrichment
BP GO:0009064 glutamine family amino acid metabolic process IEP Enrichment
BP GO:0009066 aspartate family amino acid metabolic process IEP Enrichment
BP GO:0009067 aspartate family amino acid biosynthetic process IEP Enrichment
BP GO:0009081 branched-chain amino acid metabolic process IEP Enrichment
BP GO:0009082 branched-chain amino acid biosynthetic process IEP Enrichment
BP GO:0009084 glutamine family amino acid biosynthetic process IEP Enrichment
BP GO:0009086 methionine biosynthetic process IEP Enrichment
MF GO:0015035 protein-disulfide reductase activity IEP Enrichment
MF GO:0015036 disulfide oxidoreductase activity IEP Enrichment
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Enrichment
BP GO:0015696 ammonium transport IEP Enrichment
MF GO:0015930 glutamate synthase activity IEP Enrichment
MF GO:0016211 ammonia ligase activity IEP Enrichment
MF GO:0016491 oxidoreductase activity IEP Enrichment
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Enrichment
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Enrichment
MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEP Enrichment
MF GO:0016880 acid-ammonia (or amide) ligase activity IEP Enrichment
MF GO:0022890 inorganic cation transmembrane transporter activity IEP Enrichment
BP GO:0030001 metal ion transport IEP Enrichment
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Enrichment
MF GO:0043169 cation binding IEP Enrichment
BP GO:0043650 dicarboxylic acid biosynthetic process IEP Enrichment
BP GO:0044272 sulfur compound biosynthetic process IEP Enrichment
MF GO:0046872 metal ion binding IEP Enrichment
MF GO:0046873 metal ion transmembrane transporter activity IEP Enrichment
MF GO:0051287 NAD binding IEP Enrichment
BP GO:0055114 obsolete oxidation-reduction process IEP Enrichment
BP GO:1901605 alpha-amino acid metabolic process IEP Enrichment
BP GO:1901607 alpha-amino acid biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR000891 PYR_CT 3 271
IPR013709 2-isopropylmalate_synth_dimer 368 496
No external refs found!