AKI50019 (nadC, L2625_02173)

Aliases : nadC, L2625_02173

Description : nicotinate-nucleotide pyrophosphorylase [Ensembl]. Quinolinate phosphoribosyl transferase [Interproscan].

Gene families : OG_02_0000968 (OrthoFinder) Phylogenetic Tree(s): OG0000968_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI50019
Cluster	HCCA: Cluster_10

Target	Alias	Description	ECC score	Gene Family Method
AKP14630	nadC, WX61_00551	putative nicotinate-nucleotide pyrophosphorylase...	0.03	OrthoFinder
CCG26688	No alias	Quinolinate phosphoribosyltransferase [decarboxylating]...	0.03	OrthoFinder
CCL18778	nadC, BN171_2620001	Nicotinate-nucleotide pyrophosphorylase [Ensembl]....	0.11	OrthoFinder
CCP44360	nadC, Rv1596	Probable nicotinate-nucleotide pyrophosphatase NadC...	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	None	Extended
BP	GO:0009435	NAD biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016757	glycosyltransferase activity	None	Extended
MF	GO:0016763	pentosyltransferase activity	IEA	Interproscan
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	None	Extended
BP	GO:0019362	pyridine nucleotide metabolic process	None	Extended
BP	GO:0019363	pyridine nucleotide biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0046496	nicotinamide nucleotide metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072524	pyridine-containing compound metabolic process	None	Extended
BP	GO:0072525	pyridine-containing compound biosynthetic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000105	histidine biosynthetic process	IEP	Enrichment
MF	GO:0003864	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	IEP	Enrichment
MF	GO:0003879	ATP phosphoribosyltransferase activity	IEP	Enrichment
MF	GO:0003937	IMP cyclohydrolase activity	IEP	Enrichment
MF	GO:0004019	adenylosuccinate synthase activity	IEP	Enrichment
MF	GO:0004399	histidinol dehydrogenase activity	IEP	Enrichment
MF	GO:0004592	pantoate-beta-alanine ligase activity	IEP	Enrichment
MF	GO:0004635	phosphoribosyl-AMP cyclohydrolase activity	IEP	Enrichment
MF	GO:0004637	phosphoribosylamine-glycine ligase activity	IEP	Enrichment
MF	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IEP	Enrichment
MF	GO:0004665	prephenate dehydrogenase (NADP+) activity	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006144	purine nucleobase metabolic process	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006188	IMP biosynthetic process	IEP	Enrichment
BP	GO:0006189	'de novo' IMP biosynthetic process	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006547	histidine metabolic process	IEP	Enrichment
BP	GO:0006570	tyrosine metabolic process	IEP	Enrichment
BP	GO:0006571	tyrosine biosynthetic process	IEP	Enrichment
BP	GO:0006575	cellular modified amino acid metabolic process	IEP	Enrichment
BP	GO:0006810	transport	IEP	Enrichment
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Enrichment
MF	GO:0008977	prephenate dehydrogenase (NAD+) activity	IEP	Enrichment
MF	GO:0008987	quinolinate synthetase A activity	IEP	Enrichment
BP	GO:0009113	purine nucleobase biosynthetic process	IEP	Enrichment
BP	GO:0009116	nucleoside metabolic process	IEP	Enrichment
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Enrichment
MF	GO:0015035	protein-disulfide reductase activity	IEP	Enrichment
MF	GO:0015036	disulfide oxidoreductase activity	IEP	Enrichment
BP	GO:0015939	pantothenate metabolic process	IEP	Enrichment
BP	GO:0015940	pantothenate biosynthetic process	IEP	Enrichment
CC	GO:0016020	membrane	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEP	Enrichment
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	IEP	Enrichment
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
MF	GO:0019238	cyclohydrolase activity	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Enrichment
BP	GO:0042398	cellular modified amino acid biosynthetic process	IEP	Enrichment
CC	GO:0043190	ATP-binding cassette (ABC) transporter complex	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046040	IMP metabolic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0046417	chorismate metabolic process	IEP	Enrichment
BP	GO:0051179	localization	IEP	Enrichment
BP	GO:0051234	establishment of localization	IEP	Enrichment
MF	GO:0051287	NAD binding	IEP	Enrichment
BP	GO:0055085	transmembrane transport	IEP	Enrichment
BP	GO:0072330	monocarboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0072521	purine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Enrichment
CC	GO:0098533	ATPase dependent transmembrane transport complex	IEP	Enrichment
CC	GO:0098797	plasma membrane protein complex	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901657	glycosyl compound metabolic process	IEP	Enrichment
CC	GO:1902495	transmembrane transporter complex	IEP	Enrichment
CC	GO:1904949	ATPase complex	IEP	Enrichment
CC	GO:1990351	transporter complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002638	Quinolinate_PRibosylTrfase_C	109	273
IPR022412	Quinolinate_PRibosylTrfase_N	18	107

External Links

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AKI50019 (nadC, L2625_02173)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation