AKP16198 (mutL, WX61_02174)

Aliases : mutL, WX61_02174

Description : DNA mismatch repair protein MutL [Ensembl]. Histidine kinase-, DNA mismatch repair protein, MutL C terminal dimerisation domain [Interproscan].

Gene families : OG_02_0000756 (OrthoFinder) Phylogenetic Tree(s): OG0000756_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKP16198
Cluster	HCCA: Cluster_21

Target	Alias	Description	ECC score	Gene Family Method
AAL23179	STM4359, mutL	enzyme in methyl-directed mismatch repair [Ensembl]....	0.05	OrthoFinder
AEA95121	hexB, OG1RF_12434	DNA mismatch repair protein HexB [Ensembl]. Histidine...	0.04	OrthoFinder
AKI49401	mutL, L2625_01501	DNA mismatch repair protein [Ensembl]. DNA mismatch...	0.03	OrthoFinder
CCL18232	mutL, BN171_2170019	DNA mismatch repair protein MutL [Ensembl]. MutL C...	0.03	OrthoFinder
EDJ91210	CGSHi22421_01789	DNA mismatch repair protein [Ensembl]. Histidine...	0.05	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0002097	tRNA wobble base modification	IEP	Enrichment
BP	GO:0002100	tRNA wobble adenosine to inosine editing	IEP	Enrichment
BP	GO:0002949	tRNA threonylcarbamoyladenosine modification	IEP	Enrichment
MF	GO:0003951	NAD+ kinase activity	IEP	Enrichment
MF	GO:0004000	adenosine deaminase activity	IEP	Enrichment
MF	GO:0004055	argininosuccinate synthase activity	IEP	Enrichment
MF	GO:0004107	chorismate synthase activity	IEP	Enrichment
MF	GO:0004127	cytidylate kinase activity	IEP	Enrichment
MF	GO:0004424	imidazoleglycerol-phosphate dehydratase activity	IEP	Enrichment
CC	GO:0005694	chromosome	IEP	Enrichment
BP	GO:0006284	base-excision repair	IEP	Enrichment
BP	GO:0006382	adenosine to inosine editing	IEP	Enrichment
BP	GO:0006396	RNA processing	IEP	Enrichment
BP	GO:0006400	tRNA modification	IEP	Enrichment
BP	GO:0006741	NADP biosynthetic process	IEP	Enrichment
BP	GO:0006743	ubiquinone metabolic process	IEP	Enrichment
BP	GO:0006744	ubiquinone biosynthetic process	IEP	Enrichment
BP	GO:0008033	tRNA processing	IEP	Enrichment
MF	GO:0008251	tRNA-specific adenosine deaminase activity	IEP	Enrichment
MF	GO:0008813	chorismate lyase activity	IEP	Enrichment
BP	GO:0009143	nucleoside triphosphate catabolic process	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
BP	GO:0016553	base conversion or substitution editing	IEP	Enrichment
MF	GO:0016657	oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor	IEP	Enrichment
MF	GO:0016782	transferase activity, transferring sulphur-containing groups	IEP	Enrichment
MF	GO:0016833	oxo-acid-lyase activity	IEP	Enrichment
MF	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
MF	GO:0019239	deaminase activity	IEP	Enrichment
BP	GO:0032506	cytokinetic process	IEP	Enrichment
MF	GO:0032977	membrane insertase activity	IEP	Enrichment
MF	GO:0033739	preQ1 synthase activity	IEP	Enrichment
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
BP	GO:0042180	cellular ketone metabolic process	IEP	Enrichment
BP	GO:0042181	ketone biosynthetic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
MF	GO:0051536	iron-sulfur cluster binding	IEP	Enrichment
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEP	Enrichment
MF	GO:0051540	metal cluster binding	IEP	Enrichment
BP	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process	IEP	Enrichment
BP	GO:0090529	cell septum assembly	IEP	Enrichment
MF	GO:0140104	molecular carrier activity	IEP	Enrichment
MF	GO:0140597	protein carrier activity	IEP	Enrichment
BP	GO:1901292	nucleoside phosphate catabolic process	IEP	Enrichment
BP	GO:1901661	quinone metabolic process	IEP	Enrichment
BP	GO:1901663	quinone biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR014790	MutL_C	466	614
IPR013507	DNA_mismatch_S5_2-like	208	325

External Links

No external refs found!

AKP16198 (mutL, WX61_02174)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation