AAL20982 (STM2078, hisI)

Aliases : STM2078, hisI

Description : phosphoribosyl-AMP cyclohydrolase [Ensembl]. Phosphoribosyl-AMP cyclohydrolase, Phosphoribosyl-ATP pyrophosphohydrolase [Interproscan].

Gene families : OG_02_0000827 (OrthoFinder) Phylogenetic Tree(s): OG0000827_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAL20982
Cluster	HCCA: Cluster_10

Target	Alias	Description	ECC score	Gene Family Method
AAC75087	hisI, b2026	phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP...	0.16	OrthoFinder
AGT23511	N559_1775	bifunctional phosphoribosyl-AMP...	0.08	OrthoFinder
AHY40777	CJ8421_08025	bifunctional phosphoribosyl-AMP...	0.03	OrthoFinder
AKI48511	hisI, L2625_00575	phosphoribosyl-AMP cyclohydrolase [Ensembl]....	0.07	OrthoFinder
CCL17756	hisI, BN171_1760001	Histidine biosynthesis bifunctional protein HisIE...	0.05	OrthoFinder
CCP44370	hisI, Rv1606	Probable phosphoribosyl-AMP 1,6 cyclohydrolase HisI...	0.03	OrthoFinder
CPC67916	hisI, ERS093114_01038	Phosphoribosyl-AMP cyclohydrolase / Phosphoribosyl-ATP...	0.06	OrthoFinder
EDJ91517	atpC, CGSHi22421_07097	F0F1 ATP synthase subunit epsilon [Ensembl]....	0.07	OrthoFinder
KNA53867	VCV51_030805	phosphoribosyl-ATP pyrophosphohydrolase [Ensembl]....	0.07	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0000105	histidine biosynthetic process	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004635	phosphoribosyl-AMP cyclohydrolase activity	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006547	histidine metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	None	Extended
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	None	Extended
MF	GO:0019238	cyclohydrolase activity	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003677	DNA binding	IEP	Enrichment
MF	GO:0003879	ATP phosphoribosyltransferase activity	IEP	Enrichment
MF	GO:0004399	histidinol dehydrogenase activity	IEP	Enrichment
MF	GO:0004424	imidazoleglycerol-phosphate dehydratase activity	IEP	Enrichment
MF	GO:0004455	ketol-acid reductoisomerase activity	IEP	Enrichment
MF	GO:0004518	nuclease activity	IEP	Enrichment
MF	GO:0004527	exonuclease activity	IEP	Enrichment
MF	GO:0004529	exodeoxyribonuclease activity	IEP	Enrichment
MF	GO:0004536	deoxyribonuclease activity	IEP	Enrichment
MF	GO:0004568	chitinase activity	IEP	Enrichment
MF	GO:0004834	tryptophan synthase activity	IEP	Enrichment
BP	GO:0006030	chitin metabolic process	IEP	Enrichment
BP	GO:0006032	chitin catabolic process	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006568	tryptophan metabolic process	IEP	Enrichment
BP	GO:0006576	cellular biogenic amine metabolic process	IEP	Enrichment
BP	GO:0006586	indolalkylamine metabolic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
MF	GO:0008309	double-stranded DNA exodeoxyribonuclease activity	IEP	Enrichment
MF	GO:0008409	5'-3' exonuclease activity	IEP	Enrichment
MF	GO:0008452	RNA ligase activity	IEP	Enrichment
BP	GO:0009081	branched-chain amino acid metabolic process	IEP	Enrichment
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009308	amine metabolic process	IEP	Enrichment
MF	GO:0009378	four-way junction helicase activity	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016763	pentosyltransferase activity	IEP	Enrichment
MF	GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	Enrichment
MF	GO:0016835	carbon-oxygen lyase activity	IEP	Enrichment
MF	GO:0016836	hydro-lyase activity	IEP	Enrichment
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Enrichment
MF	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	IEP	Enrichment
BP	GO:0019076	viral release from host cell	IEP	Enrichment
BP	GO:0019835	cytolysis	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
MF	GO:0035312	5'-3' exodeoxyribonuclease activity	IEP	Enrichment
BP	GO:0035890	exit from host	IEP	Enrichment
BP	GO:0035891	exit from host cell	IEP	Enrichment
BP	GO:0042430	indole-containing compound metabolic process	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0044106	cellular amine metabolic process	IEP	Enrichment
BP	GO:0044403	biological process involved in symbiotic interaction	IEP	Enrichment
BP	GO:0046348	amino sugar catabolic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051701	biological process involved in interaction with host	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
MF	GO:0051908	double-stranded DNA 5'-3' exodeoxyribonuclease activity	IEP	Enrichment
BP	GO:0052126	movement in host environment	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
BP	GO:1901071	glucosamine-containing compound metabolic process	IEP	Enrichment
BP	GO:1901072	glucosamine-containing compound catabolic process	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR021130	PRib-ATP_PPHydrolase-like	116	202
IPR002496	PRib_AMP_CycHydrolase_dom	33	105

External Links

No external refs found!

AAL20982 (STM2078, hisI)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation