Coexpression cluster: Cluster_10 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0016053 organic acid biosynthetic process 20.97% (13/62) 4.9 0.0 0.0
GO:0008652 cellular amino acid biosynthetic process 17.74% (11/62) 5.13 0.0 0.0
GO:0046394 carboxylic acid biosynthetic process 17.74% (11/62) 4.85 0.0 0.0
GO:0006520 cellular amino acid metabolic process 22.58% (14/62) 3.86 0.0 0.0
GO:0006082 organic acid metabolic process 24.19% (15/62) 3.45 0.0 0.0
GO:0044283 small molecule biosynthetic process 20.97% (13/62) 3.79 0.0 0.0
GO:0006547 histidine metabolic process 9.68% (6/62) 6.2 0.0 0.0
GO:0000105 histidine biosynthetic process 9.68% (6/62) 6.2 0.0 0.0
GO:0019752 carboxylic acid metabolic process 22.58% (14/62) 3.44 0.0 0.0
GO:0043436 oxoacid metabolic process 22.58% (14/62) 3.44 0.0 0.0
GO:0044281 small molecule metabolic process 24.19% (15/62) 2.55 0.0 0.0
GO:1901566 organonitrogen compound biosynthetic process 20.97% (13/62) 2.81 0.0 0.0
GO:0009058 biosynthetic process 25.81% (16/62) 2.16 0.0 4e-06
GO:0044249 cellular biosynthetic process 20.97% (13/62) 2.22 3e-06 3.5e-05
GO:1901564 organonitrogen compound metabolic process 24.19% (15/62) 1.98 3e-06 3.9e-05
GO:1901576 organic substance biosynthetic process 20.97% (13/62) 2.14 5e-06 5.8e-05
GO:1901607 alpha-amino acid biosynthetic process 6.45% (4/62) 4.5 2e-05 0.000233
GO:0036094 small molecule binding 22.58% (14/62) 1.65 9e-05 0.000975
GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3.23% (2/62) 6.2 0.000182 0.001872
GO:1901605 alpha-amino acid metabolic process 6.45% (4/62) 3.5 0.000372 0.003628
GO:0006807 nitrogen compound metabolic process 24.19% (15/62) 1.32 0.00064 0.005947
GO:0016887 ATPase 9.68% (6/62) 2.34 0.001066 0.00945
GO:0008152 metabolic process 30.65% (19/62) 0.99 0.00187 0.015856
GO:0044237 cellular metabolic process 24.19% (15/62) 1.15 0.002063 0.016758
GO:0044238 primary metabolic process 24.19% (15/62) 1.13 0.002373 0.018506
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3.23% (2/62) 4.61 0.002641 0.01981
GO:0051287 NAD binding 4.84% (3/62) 3.32 0.003078 0.022228
GO:0043648 dicarboxylic acid metabolic process 3.23% (2/62) 4.39 0.003665 0.024647
GO:0009067 aspartate family amino acid biosynthetic process 3.23% (2/62) 4.39 0.003665 0.024647
GO:0009987 cellular process 37.1% (23/62) 0.77 0.004094 0.024949
GO:0000166 nucleotide binding 16.13% (10/62) 1.4 0.003974 0.025001
GO:1901265 nucleoside phosphate binding 16.13% (10/62) 1.4 0.003974 0.025001
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3.23% (2/62) 4.2 0.004844 0.028626
GO:0043167 ion binding 19.35% (12/62) 1.19 0.00517 0.029654
GO:0071704 organic substance metabolic process 25.81% (16/62) 0.97 0.005361 0.029868
GO:0046983 protein dimerization activity 3.23% (2/62) 4.03 0.006174 0.032539
GO:0009066 aspartate family amino acid metabolic process 3.23% (2/62) 4.03 0.006174 0.032539
GO:0015977 carbon fixation 1.61% (1/62) 6.2 0.013614 0.047407
GO:0004455 ketol-acid reductoisomerase activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0008964 phosphoenolpyruvate carboxylase activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0004356 glutamate-ammonia ligase activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0015696 ammonium transport 1.61% (1/62) 6.2 0.013614 0.047407
GO:0006542 glutamine biosynthetic process 1.61% (1/62) 6.2 0.013614 0.047407
GO:0003879 ATP phosphoribosyltransferase activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0008705 methionine synthase activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0004665 prephenate dehydrogenase (NADP+) activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0006570 tyrosine metabolic process 1.61% (1/62) 6.2 0.013614 0.047407
GO:0008839 4-hydroxy-tetrahydrodipicolinate reductase 1.61% (1/62) 6.2 0.013614 0.047407
GO:0004635 phosphoribosyl-AMP cyclohydrolase activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0006571 tyrosine biosynthetic process 1.61% (1/62) 6.2 0.013614 0.047407
GO:0008977 prephenate dehydrogenase (NAD+) activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0004424 imidazoleglycerol-phosphate dehydratase activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0008519 ammonium transmembrane transporter activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0004399 histidinol dehydrogenase activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0042084 5-methyltetrahydrofolate-dependent methyltransferase activity 1.61% (1/62) 6.2 0.013614 0.047407
GO:0055114 obsolete oxidation-reduction process 11.29% (7/62) 1.44 0.01388 0.047483
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Campylobacter jejuni HCCA Cluster_9 0.028 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_11 0.041 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_18 0.029 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_27 0.033 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_28 0.03 OrthoFinder Compare
Escherichia coli HCCA Cluster_7 0.116 OrthoFinder Compare
Escherichia coli HCCA Cluster_11 0.06 OrthoFinder Compare
Escherichia coli HCCA Cluster_18 0.066 OrthoFinder Compare
Escherichia coli HCCA Cluster_32 0.093 OrthoFinder Compare
Escherichia coli HCCA Cluster_34 0.059 OrthoFinder Compare
Escherichia coli HCCA Cluster_37 0.058 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_2 0.034 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_3 0.054 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_8 0.032 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_9 0.043 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_11 0.201 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_43 0.057 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_50 0.028 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_7 0.036 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_10 0.051 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_15 0.099 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_13 0.034 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_35 0.043 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_2 0.034 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_12 0.041 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_17 0.032 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_24 0.051 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_31 0.044 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_39 0.038 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_47 0.033 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_53 0.029 OrthoFinder Compare
Salmonella enterica HCCA Cluster_39 0.033 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_1 0.1 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_1 0.039 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_17 0.028 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_2 0.045 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_5 0.048 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_10 0.06 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_14 0.027 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_15 0.038 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_25 0.069 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_28 0.028 OrthoFinder Compare
Sequences (62) (download table)

InterPro Domains

GO Terms

Family Terms