AAL22838 (STM3999, polA)

Aliases : STM3999, polA

Description : DNA polymerase I [Ensembl]. 5'-3' exonuclease, 3'-5' exonuclease, DNA polymerase family A [Interproscan].

Gene families : OG_02_0000357 (OrthoFinder) Phylogenetic Tree(s): OG0000357_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAL22838
Cluster	HCCA: Cluster_35

Target	Alias	Description	ECC score	Gene Family Method
AAC76861	polA, b3863	5' to 3' DNA polymerase and 3' to 5'/5' to 3'...	0.15	OrthoFinder
AKP15249	polA, WX61_01200	DNA polymerase I [Ensembl]. 5'-3' exonuclease, 3'-5'...	0.04	OrthoFinder
CCG26484	No alias	DNA polymerase I [Ensembl]. 5'-3' exonuclease, DNA...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	Interproscan
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	IEA	Interproscan
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008408	3'-5' exonuclease activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0034061	DNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001514	selenocysteine incorporation	IEP	Enrichment
MF	GO:0003700	DNA-binding transcription factor activity	IEP	Enrichment
MF	GO:0004340	glucokinase activity	IEP	Enrichment
MF	GO:0004345	glucose-6-phosphate dehydrogenase activity	IEP	Enrichment
MF	GO:0004347	glucose-6-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004396	hexokinase activity	IEP	Enrichment
MF	GO:0004476	mannose-6-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004620	phospholipase activity	IEP	Enrichment
MF	GO:0004743	pyruvate kinase activity	IEP	Enrichment
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Enrichment
MF	GO:0005536	glucose binding	IEP	Enrichment
BP	GO:0005975	carbohydrate metabolic process	IEP	Enrichment
BP	GO:0005996	monosaccharide metabolic process	IEP	Enrichment
BP	GO:0006006	glucose metabolic process	IEP	Enrichment
BP	GO:0006090	pyruvate metabolic process	IEP	Enrichment
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Enrichment
BP	GO:0006096	glycolytic process	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	Enrichment
BP	GO:0006304	DNA modification	IEP	Enrichment
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Enrichment
BP	GO:0006417	regulation of translation	IEP	Enrichment
BP	GO:0006451	translational readthrough	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006757	ATP generation from ADP	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
BP	GO:0009056	catabolic process	IEP	Enrichment
BP	GO:0009116	nucleoside metabolic process	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009135	purine nucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009185	ribonucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009889	regulation of biosynthetic process	IEP	Enrichment
BP	GO:0010468	regulation of gene expression	IEP	Enrichment
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0010608	posttranscriptional regulation of gene expression	IEP	Enrichment
BP	GO:0016052	carbohydrate catabolic process	IEP	Enrichment
MF	GO:0016298	lipase activity	IEP	Enrichment
BP	GO:0016310	phosphorylation	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016657	oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor	IEP	Enrichment
MF	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	IEP	Enrichment
MF	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor	IEP	Enrichment
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Enrichment
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Enrichment
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0019222	regulation of metabolic process	IEP	Enrichment
BP	GO:0019318	hexose metabolic process	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
MF	GO:0030955	potassium ion binding	IEP	Enrichment
BP	GO:0031323	regulation of cellular metabolic process	IEP	Enrichment
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Enrichment
MF	GO:0031420	alkali metal ion binding	IEP	Enrichment
BP	GO:0032268	regulation of cellular protein metabolic process	IEP	Enrichment
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Enrichment
MF	GO:0033739	preQ1 synthase activity	IEP	Enrichment
BP	GO:0034248	regulation of cellular amide metabolic process	IEP	Enrichment
MF	GO:0042279	nitrite reductase (cytochrome, ammonia-forming) activity	IEP	Enrichment
BP	GO:0046031	ADP metabolic process	IEP	Enrichment
BP	GO:0046034	ATP metabolic process	IEP	Enrichment
BP	GO:0046939	nucleotide phosphorylation	IEP	Enrichment
BP	GO:0050789	regulation of biological process	IEP	Enrichment
BP	GO:0050794	regulation of cellular process	IEP	Enrichment
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Enrichment
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0051246	regulation of protein metabolic process	IEP	Enrichment
BP	GO:0051252	regulation of RNA metabolic process	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Enrichment
BP	GO:0065007	biological regulation	IEP	Enrichment
BP	GO:0072521	purine-containing compound metabolic process	IEP	Enrichment
BP	GO:0080090	regulation of primary metabolic process	IEP	Enrichment
MF	GO:0098809	nitrite reductase activity	IEP	Enrichment
MF	GO:0140110	transcription regulator activity	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901575	organic substance catabolic process	IEP	Enrichment
BP	GO:1901657	glycosyl compound metabolic process	IEP	Enrichment
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Enrichment
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR020045	DNA_polI_H3TH	171	270
IPR020046	5-3_exonucl_a-hlix_arch_N	9	170
IPR001098	DNA-dir_DNA_pol_A_palm_dom	552	925
IPR002562	3'-5'_exonuclease_dom	330	517

External Links

No external refs found!

AAL22838 (STM3999, polA)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation