CCG26322 (MutL)

Aliases : MutL

Description : DNA mismatch repair protein MutL [Ensembl]. Histidine kinase-, DNA mismatch repair protein, MutL C terminal dimerisation domain [Interproscan].

Gene families : OG_02_0000756 (OrthoFinder) Phylogenetic Tree(s): OG0000756_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCG26322
Cluster	HCAA: Cluster_10

Target	Alias	Description	ECC score	Gene Family Method
AAL23179	STM4359, mutL	enzyme in methyl-directed mismatch repair [Ensembl]....	0.03	OrthoFinder
AKI49401	mutL, L2625_01501	DNA mismatch repair protein [Ensembl]. DNA mismatch...	0.03	OrthoFinder
CRO54409	mutL	DNA mismatch repair protein MutL [Ensembl]. Histidine...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0003684	damaged DNA binding	IEP	Enrichment
MF	GO:0003747	translation release factor activity	IEP	Enrichment
MF	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IEP	Enrichment
MF	GO:0004140	dephospho-CoA kinase activity	IEP	Enrichment
MF	GO:0004150	dihydroneopterin aldolase activity	IEP	Enrichment
MF	GO:0004476	mannose-6-phosphate isomerase activity	IEP	Enrichment
BP	GO:0006109	regulation of carbohydrate metabolic process	IEP	Enrichment
BP	GO:0006284	base-excision repair	IEP	Enrichment
BP	GO:0006289	nucleotide-excision repair	IEP	Enrichment
BP	GO:0006415	translational termination	IEP	Enrichment
MF	GO:0008079	translation termination factor activity	IEP	Enrichment
MF	GO:0008270	zinc ion binding	IEP	Enrichment
MF	GO:0009378	four-way junction helicase activity	IEP	Enrichment
MF	GO:0015075	ion transmembrane transporter activity	IEP	Enrichment
MF	GO:0015128	gluconate transmembrane transporter activity	IEP	Enrichment
MF	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	IEP	Enrichment
MF	GO:0016832	aldehyde-lyase activity	IEP	Enrichment
BP	GO:0022411	cellular component disassembly	IEP	Enrichment
BP	GO:0032984	protein-containing complex disassembly	IEP	Enrichment
MF	GO:0042879	aldonate transmembrane transporter activity	IEP	Enrichment
BP	GO:0043624	cellular protein complex disassembly	IEP	Enrichment
MF	GO:0046914	transition metal ion binding	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR014790	MutL_C	462	604
IPR013507	DNA_mismatch_S5_2-like	209	326

External Links

No external refs found!

CCG26322 (MutL)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation