CCG27509

Description : DNA topoisomerase I [Ensembl]. Toprim domain, DNA topoisomerase, Topoisomerase DNA binding C4 zinc finger [Interproscan].

Gene families : OG_02_0000393 (OrthoFinder) Phylogenetic Tree(s): OG0000393_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCG27509
Cluster	HCAA: Cluster_11

Target	Alias	Description	ECC score	Gene Family Method
AAK99944	spr1141, topA	DNA topoisomerase I [Ensembl]. Toprim domain, DNA...	0.05	OrthoFinder
AAL20632	STM1714, topA	DNA topoisomerase type I, omega protein [Ensembl]....	0.08	OrthoFinder
ADK86690	topA, MPNE_0293	DNA topoisomerase I [Ensembl]. Toprim domain [Interproscan].	0.03	OrthoFinder
AGT24669	N559_3006	DNA topoisomerase I [Ensembl]. Toprim domain [InterProScan].	0.06	OrthoFinder
AHY40871	CJ8421_08495	DNA topoisomerase I [Ensembl]. Toprim domain, DNA...	0.03	OrthoFinder
AKI49271	topA, L2625_01365	DNA topoisomerase I [Ensembl]. TOPRIM domain, DNA...	0.04	OrthoFinder
CRO91125	topA_2	DNA topoisomerase 1 [Ensembl]. Toprim domain, DNA...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000921	septin ring assembly	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003735	structural constituent of ribosome	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005198	structural molecule activity	IEP	Enrichment
CC	GO:0005840	ribosome	IEP	Enrichment
CC	GO:0005856	cytoskeleton	IEP	Enrichment
CC	GO:0005940	septin ring	IEP	Enrichment
BP	GO:0006412	translation	IEP	Enrichment
BP	GO:0006518	peptide metabolic process	IEP	Enrichment
BP	GO:0007010	cytoskeleton organization	IEP	Enrichment
MF	GO:0008312	7S RNA binding	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
BP	GO:0019538	protein metabolic process	IEP	Enrichment
BP	GO:0031106	septin ring organization	IEP	Enrichment
CC	GO:0032156	septin cytoskeleton	IEP	Enrichment
BP	GO:0032185	septin cytoskeleton organization	IEP	Enrichment
BP	GO:0032784	regulation of DNA-templated transcription, elongation	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0043043	peptide biosynthetic process	IEP	Enrichment
BP	GO:0043603	cellular amide metabolic process	IEP	Enrichment
BP	GO:0043604	amide biosynthetic process	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044267	cellular protein metabolic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
CC	GO:0048500	signal recognition particle	IEP	Enrichment
BP	GO:0070925	organelle assembly	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
CC	GO:1990904	ribonucleoprotein complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006171	TOPRIM_domain	6	72
IPR013497	Topo_IA_cen	87	500
IPR013498	Topo_IA_Znf	530	565
IPR013498	Topo_IA_Znf	609	641
IPR013498	Topo_IA_Znf	569	606

External Links

No external refs found!

CCG27509

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation