CCP44899 (metH, Rv2124c)

Aliases : metH, Rv2124c

Description : 5-methyltetrahydrofolate--homocystein methyltransferase MetH (methionine synthase, vitamin-B12 dependent isozyme) (ms) [Ensembl]. B12 binding domain, Pterin binding enzyme, Homocysteine S-methyltransferase, Vitamin B12 dependent methionine synthase [Interproscan].

Gene families : OG_02_0000961 (OrthoFinder) Phylogenetic Tree(s): OG0000961_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCP44899
Cluster	HCCA: Cluster_44

Target	Alias	Description	ECC score	Gene Family Method	Actions
AAC73364	mmuM, b0261	CP4-6 prophage; S-methylmethionine:homocysteine...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	None	Extended
BP	GO:0000097	sulfur amino acid biosynthetic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006555	methionine metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	None	Extended
MF	GO:0008172	S-methyltransferase activity	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
MF	GO:0008705	methionine synthase activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009066	aspartate family amino acid metabolic process	None	Extended
BP	GO:0009067	aspartate family amino acid biosynthetic process	None	Extended
BP	GO:0009086	methionine biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0019842	vitamin binding	None	Extended
MF	GO:0031419	cobalamin binding	IEA	Interproscan
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	None	Extended
BP	GO:0042558	pteridine-containing compound metabolic process	IEA	Interproscan
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044272	sulfur compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	IEA	Interproscan
MF	GO:0046906	tetrapyrrole binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended
BP	GO:1901607	alpha-amino acid biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004144	diacylglycerol O-acyltransferase activity	IEP	Enrichment
MF	GO:0004478	methionine adenosyltransferase activity	IEP	Enrichment
BP	GO:0006556	S-adenosylmethionine biosynthetic process	IEP	Enrichment
MF	GO:0008374	O-acyltransferase activity	IEP	Enrichment
MF	GO:0016411	acylglycerol O-acyltransferase activity	IEP	Enrichment
BP	GO:0045017	glycerolipid biosynthetic process	IEP	Enrichment
BP	GO:0046486	glycerolipid metabolic process	IEP	Enrichment
BP	GO:0046500	S-adenosylmethionine metabolic process	IEP	Enrichment
MF	GO:0051536	iron-sulfur cluster binding	IEP	Enrichment
MF	GO:0051540	metal cluster binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR000489	Pterin-binding_dom	326	562
IPR003759	Cbl-bd_cap	624	696
IPR004223	VitB12-dep_Met_synth_activ_dom	957	1171
IPR006158	Cobalamin-bd	710	827
IPR003726	HCY_dom	2	291

External Links

No external refs found!

CCP44899 (metH, Rv2124c)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation