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CCP45172 (mbtA, Rv2384)


Aliases : mbtA, Rv2384

Description : Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase [Ensembl]. AMP-binding enzyme C-terminal domain [Interproscan].


Gene families : OG_02_0000029 (OrthoFinder) Phylogenetic Tree(s): OG0000029_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: CCP45172
Cluster HCCA: Cluster_17

Target Alias Description ECC score Gene Family Method Actions
AAC73695 entE, b0594 2,3-dihydroxybenzoate-AMP ligase component of... 0.02 OrthoFinder
AAL19547 STM0596, entE 2,3-dihydroxybenzoate-AMP ligase [Ensembl]. AMP-binding... 0.02 OrthoFinder
CCP45386 fadD9, Rv2590 Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA... 0.05 OrthoFinder
CCP45752 fadD22, Rv2948c P-hydroxybenzoyl-AMP ligase FadD22 [Ensembl].... 0.04 OrthoFinder
CCP45898 fadD13, Rv3089 Probable chain-fatty-acid-CoA ligase FadD13... 0.04 OrthoFinder
CCP46335 fadD18, Rv3513c Probable fatty-acid-CoA ligase FadD18 (fragment)... 0.06 OrthoFinder
CRO74822 dhbE 2,3-dihydroxybenzoate-AMP ligase [Ensembl]. AMP-binding... 0.02 OrthoFinder
CRP28398 No alias Long-chain-fatty-acid--CoA ligase FadD15 [Ensembl].... 0.03 OrthoFinder
EDJ91610 CGSHi22421_07562 acyl-CoA synthase [Ensembl]. AMP-binding enzyme... 0.02 OrthoFinder
KNA56884 VCV51_030519 2,3-dihydroxybenzoate-AMP ligase [Ensembl]. AMP-binding... 0.03 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
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Type GO Term Name Evidence Source
BP GO:0000105 histidine biosynthetic process IEP Enrichment
MF GO:0000287 magnesium ion binding IEP Enrichment
MF GO:0003879 ATP phosphoribosyltransferase activity IEP Enrichment
CC GO:0005737 cytoplasm IEP Enrichment
BP GO:0006547 histidine metabolic process IEP Enrichment
BP GO:0009116 nucleoside metabolic process IEP Enrichment
MF GO:0015399 primary active transmembrane transporter activity IEP Enrichment
MF GO:0016763 pentosyltransferase activity IEP Enrichment
MF GO:0016887 ATPase IEP Enrichment
MF GO:0022804 active transmembrane transporter activity IEP Enrichment
MF GO:0042626 ATPase-coupled transmembrane transporter activity IEP Enrichment
BP GO:1901657 glycosyl compound metabolic process IEP Enrichment
InterPro domains Description Start Stop
IPR000873 AMP-dep_Synth/Lig 48 457
IPR025110 AMP-bd_C 468 542
UniProtKB P71716