CCP46429 (folK, Rv3606c)

Aliases : folK, Rv3606c

Description : 2-amino-4-hydroxy-6-hydroxymethyldihydropteridinepyrophosphokinase FolK (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK) (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase) (7,8-dihydro-6-hydroxymethylpterin-diphosphokinase) (6-hydroxymethyl-7,8-dihydropterin diphosphokinase) [Ensembl]. 7 [Interproscan].

Gene families : OG_02_0000420 (OrthoFinder) Phylogenetic Tree(s): OG0000420_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCP46429
Cluster	HCCA: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method
AAK99073	spr0269, sulD	Aldolase-pyrophosphokinase [Ensembl]. 7,...	0.03	OrthoFinder
AEA95204	folK, OG1RF_12517	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine...	0.07	OrthoFinder
AGT25897	N559_4277	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine...	0.02	OrthoFinder
AKI48194	folK, L2625_00228	2-amino-4-hydroxy-6-hydroxymethyldihydropteridinepyrophos...	0.03	OrthoFinder
AKP15698	folK, WX61_01663	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine...	0.03	OrthoFinder
CCG27577	No alias	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine...	0.03	OrthoFinder
CCL17638	folK, BN171_1640028	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine...	0.03	OrthoFinder
KNA51848	VCV51_033531	7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003848	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	IEA	Interproscan
BP	GO:0006575	cellular modified amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006760	folic acid-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009396	folic acid-containing compound biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016778	diphosphotransferase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0042398	cellular modified amino acid biosynthetic process	None	Extended
BP	GO:0042558	pteridine-containing compound metabolic process	None	Extended
BP	GO:0042559	pteridine-containing compound biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000105	histidine biosynthetic process	IEP	Enrichment
BP	GO:0002949	tRNA threonylcarbamoyladenosine modification	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004150	dihydroneopterin aldolase activity	IEP	Enrichment
MF	GO:0004635	phosphoribosyl-AMP cyclohydrolase activity	IEP	Enrichment
BP	GO:0006066	alcohol metabolic process	IEP	Enrichment
BP	GO:0006400	tRNA modification	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006547	histidine metabolic process	IEP	Enrichment
MF	GO:0008144	drug binding	IEP	Enrichment
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Enrichment
MF	GO:0008658	penicillin binding	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
BP	GO:0016311	dephosphorylation	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016832	aldehyde-lyase activity	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
MF	GO:0019238	cyclohydrolase activity	IEP	Enrichment
BP	GO:0019751	polyol metabolic process	IEP	Enrichment
MF	GO:0031406	carboxylic acid binding	IEP	Enrichment
MF	GO:0033218	amide binding	IEP	Enrichment
MF	GO:0033293	monocarboxylic acid binding	IEP	Enrichment
BP	GO:0043647	inositol phosphate metabolic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046164	alcohol catabolic process	IEP	Enrichment
BP	GO:0046174	polyol catabolic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0046434	organophosphate catabolic process	IEP	Enrichment
BP	GO:0046838	phosphorylated carbohydrate dephosphorylation	IEP	Enrichment
BP	GO:0046855	inositol phosphate dephosphorylation	IEP	Enrichment
BP	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process	IEP	Enrichment
BP	GO:0071545	inositol phosphate catabolic process	IEP	Enrichment
BP	GO:1901615	organic hydroxy compound metabolic process	IEP	Enrichment
BP	GO:1901616	organic hydroxy compound catabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR000550	Hppk	5	139

External Links

No external refs found!

CCP46429 (folK, Rv3606c)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation