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AEA94015 (pflA, OG1RF_11328)


Aliases : pflA, OG1RF_11328

Description : pyruvate formate-lyase activating enzyme [Ensembl]. Radical SAM superfamily, 4Fe-4S single cluster domain [Interproscan].


Gene families : OG_02_0000132 (OrthoFinder) Phylogenetic Tree(s): OG0000132_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AEA94015
Cluster HCCA: Cluster_25

Target Alias Description ECC score Gene Family Method Actions
AAC73988 pflA, b0902 pyruvate formate-lyase 1-activating enzyme;... 0.02 OrthoFinder
CCG27719 No alias Pyruvate formate-lyase activating enzyme [Ensembl].... 0.04 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0051536 iron-sulfur cluster binding IEA Interproscan
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Type GO Term Name Evidence Source
MF GO:0004417 hydroxyethylthiazole kinase activity IEP Enrichment
MF GO:0004470 malic enzyme activity IEP Enrichment
MF GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity IEP Enrichment
BP GO:0006084 acetyl-CoA metabolic process IEP Enrichment
BP GO:0006637 acyl-CoA metabolic process IEP Enrichment
BP GO:0006772 thiamine metabolic process IEP Enrichment
BP GO:0006814 sodium ion transport IEP Enrichment
BP GO:0006873 cellular ion homeostasis IEP Enrichment
BP GO:0006875 cellular metal ion homeostasis IEP Enrichment
BP GO:0006879 cellular iron ion homeostasis IEP Enrichment
MF GO:0008199 ferric iron binding IEP Enrichment
MF GO:0008410 CoA-transferase activity IEP Enrichment
MF GO:0008771 [citrate (pro-3S)-lyase] ligase activity IEP Enrichment
MF GO:0008814 citrate CoA-transferase activity IEP Enrichment
MF GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity IEP Enrichment
BP GO:0009228 thiamine biosynthetic process IEP Enrichment
CC GO:0009346 ATP-independent citrate lyase complex IEP Enrichment
BP GO:0016310 phosphorylation IEP Enrichment
MF GO:0016491 oxidoreductase activity IEP Enrichment
MF GO:0016615 malate dehydrogenase activity IEP Enrichment
MF GO:0016684 oxidoreductase activity, acting on peroxide as acceptor IEP Enrichment
MF GO:0016740 transferase activity IEP Enrichment
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Enrichment
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Enrichment
MF GO:0016782 transferase activity, transferring sulphur-containing groups IEP Enrichment
MF GO:0016829 lyase activity IEP Enrichment
MF GO:0016877 ligase activity, forming carbon-sulfur bonds IEP Enrichment
MF GO:0016878 acid-thiol ligase activity IEP Enrichment
BP GO:0019725 cellular homeostasis IEP Enrichment
BP GO:0030003 cellular cation homeostasis IEP Enrichment
BP GO:0035383 thioester metabolic process IEP Enrichment
BP GO:0042180 cellular ketone metabolic process IEP Enrichment
BP GO:0042181 ketone biosynthetic process IEP Enrichment
BP GO:0042592 homeostatic process IEP Enrichment
BP GO:0042723 thiamine-containing compound metabolic process IEP Enrichment
BP GO:0042724 thiamine-containing compound biosynthetic process IEP Enrichment
BP GO:0045149 acetoin metabolic process IEP Enrichment
BP GO:0045151 acetoin biosynthetic process IEP Enrichment
BP GO:0045454 cell redox homeostasis IEP Enrichment
BP GO:0046165 alcohol biosynthetic process IEP Enrichment
BP GO:0046916 cellular transition metal ion homeostasis IEP Enrichment
MF GO:0046917 triphosphoribosyl-dephospho-CoA synthase activity IEP Enrichment
MF GO:0047605 acetolactate decarboxylase activity IEP Enrichment
BP GO:0051191 prosthetic group biosynthetic process IEP Enrichment
MF GO:0051920 peroxiredoxin activity IEP Enrichment
BP GO:0055072 iron ion homeostasis IEP Enrichment
BP GO:0055082 cellular chemical homeostasis IEP Enrichment
BP GO:0055114 obsolete oxidation-reduction process IEP Enrichment
BP GO:0065008 regulation of biological quality IEP Enrichment
BP GO:1901617 organic hydroxy compound biosynthetic process IEP Enrichment
BP GO:1902652 secondary alcohol metabolic process IEP Enrichment
BP GO:1902653 secondary alcohol biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR007197 rSAM 26 185
No external refs found!