AEA94759 (mutY, OG1RF_12072)

Aliases : mutY, OG1RF_12072

Description : A/G-specific adenine glycosylase [Ensembl]. NUDIX domain, Helix-hairpin-helix motif, Iron-sulfur binding domain of endonuclease III, HhH-GPD superfamily base excision DNA repair protein [Interproscan].

Gene families : OG_02_0000830 (OrthoFinder) Phylogenetic Tree(s): OG0000830_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AEA94759
Cluster	HCCA: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method
AAK99911	spr1108, mutY	Similar to A/G-specific adenine glycosylase [Ensembl]....	0.04	OrthoFinder
AHY40793	CJ8421_08105	A/G-specific adenine glycosylase [Ensembl]....	0.03	OrthoFinder
AKP16234	mutY, WX61_02210	A/G-specific adenine glycosylase [Ensembl]. NUDIX...	0.03	OrthoFinder
CPD01787	mutY, ERS093114_01836	A/G-specific adenine glycosylase [Ensembl]. NUDIX...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006284	base-excision repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
MF	GO:0051536	iron-sulfur cluster binding	None	Extended
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEA	Interproscan
MF	GO:0051540	metal cluster binding	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003678	DNA helicase activity	IEP	Enrichment
MF	GO:0004386	helicase activity	IEP	Enrichment
MF	GO:0004788	thiamine diphosphokinase activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
BP	GO:0006282	regulation of DNA repair	IEP	Enrichment
BP	GO:0006353	DNA-templated transcription, termination	IEP	Enrichment
BP	GO:0008033	tRNA processing	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008144	drug binding	IEP	Enrichment
MF	GO:0008658	penicillin binding	IEP	Enrichment
BP	GO:0009229	thiamine diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009403	toxin biosynthetic process	IEP	Enrichment
BP	GO:0009404	toxin metabolic process	IEP	Enrichment
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0017150	tRNA dihydrouridine synthase activity	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019748	secondary metabolic process	IEP	Enrichment
MF	GO:0030975	thiamine binding	IEP	Enrichment
MF	GO:0031406	carboxylic acid binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
MF	GO:0033218	amide binding	IEP	Enrichment
MF	GO:0033293	monocarboxylic acid binding	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0042357	thiamine diphosphate metabolic process	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0044550	secondary metabolite biosynthetic process	IEP	Enrichment
BP	GO:0048583	regulation of response to stimulus	IEP	Enrichment
MF	GO:0050660	flavin adenine dinucleotide binding	IEP	Enrichment
BP	GO:0051052	regulation of DNA metabolic process	IEP	Enrichment
BP	GO:0080134	regulation of response to stress	IEP	Enrichment
BP	GO:0080135	regulation of cellular response to stress	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
MF	GO:1901681	sulfur compound binding	IEP	Enrichment
BP	GO:2001020	regulation of response to DNA damage stimulus	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR000445	HhH_motif	110	136
IPR003651	Endonuclease3_FeS-loop_motif	203	219
IPR029119	MutY_C	248	385
IPR003265	HhH-GPD_domain	46	171

External Links

No external refs found!

AEA94759 (mutY, OG1RF_12072)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation