AAC73260 (mrcB, b0149)


Aliases : mrcB, b0149

Description : fused glycosyl transferase and transpeptidase [Ensembl]. Bifunctional transglycosylase second domain, Penicillin binding protein transpeptidase domain, Transmembrane domain of transglycosylase PBP1 at N-terminal [Interproscan].


Gene families : OG_02_0000069 (OrthoFinder) Phylogenetic Tree(s): OG0000069_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AAC73260
Cluster HCCA: Cluster_45

Target Alias Description ECC score Gene Family Method Actions
AAL00626 spr1823, pbp2a Penicillin-binding protein 2a [Ensembl].... 0.02 OrthoFinder
AAL19154 STM0190, mrcB transpeptidase of penicillin-binding protein 1b... 0.05 OrthoFinder
AAL22355 STM3493, mrcA transpeptidase of penicillin-binding protein 1a... 0.03 OrthoFinder
AEA94137 pbp1B, OG1RF_11450 penicillin-binding protein 1B [Ensembl].... 0.03 OrthoFinder
AGT22201 N559_0388 peptidoglycan synthetase [Ensembl]. Penicillin-binding... 0.03 OrthoFinder
CRO22459 mrcB Murein polymerase [Ensembl]. Bifunctional... 0.03 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0008658 penicillin binding IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEP Enrichment
MF GO:0004222 metalloendopeptidase activity IEP Enrichment
CC GO:0005575 cellular_component IEP Enrichment
BP GO:0006081 cellular aldehyde metabolic process IEP Enrichment
BP GO:0006090 pyruvate metabolic process IEP Enrichment
BP GO:0006364 rRNA processing IEP Enrichment
BP GO:0006396 RNA processing IEP Enrichment
MF GO:0008168 methyltransferase activity IEP Enrichment
MF GO:0008170 N-methyltransferase activity IEP Enrichment
MF GO:0008649 rRNA methyltransferase activity IEP Enrichment
MF GO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEP Enrichment
MF GO:0008990 rRNA (guanine-N2-)-methyltransferase activity IEP Enrichment
BP GO:0009240 isopentenyl diphosphate biosynthetic process IEP Enrichment
CC GO:0016020 membrane IEP Enrichment
BP GO:0016072 rRNA metabolic process IEP Enrichment
MF GO:0016435 rRNA (guanine) methyltransferase activity IEP Enrichment
MF GO:0016725 oxidoreductase activity, acting on CH or CH2 groups IEP Enrichment
MF GO:0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor IEP Enrichment
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Enrichment
MF GO:0016853 isomerase activity IEP Enrichment
MF GO:0016859 cis-trans isomerase activity IEP Enrichment
BP GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Enrichment
BP GO:0019682 glyceraldehyde-3-phosphate metabolic process IEP Enrichment
BP GO:0034470 ncRNA processing IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
BP GO:0046490 isopentenyl diphosphate metabolic process IEP Enrichment
BP GO:0050992 dimethylallyl diphosphate biosynthetic process IEP Enrichment
BP GO:0050993 dimethylallyl diphosphate metabolic process IEP Enrichment
MF GO:0051745 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity IEP Enrichment
BP GO:0055085 transmembrane transport IEP Enrichment
CC GO:0110165 cellular anatomical entity IEP Enrichment
MF GO:0140096 catalytic activity, acting on a protein IEP Enrichment
MF GO:0140102 catalytic activity, acting on a rRNA IEP Enrichment
InterPro domains Description Start Stop
IPR028166 UB2H 113 197
IPR001264 Glyco_trans_51 209 380
IPR032730 PBP1b_TM 1 79
IPR001460 PCN-bd_Tpept 473 714
UniProtKB P02919