AAC74924 (pykA, b1854)

Aliases : pykA, b1854

Description : pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].

Gene families : OG_02_0000218 (OrthoFinder) Phylogenetic Tree(s): OG0000218_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC74924
Cluster	HCCA: Cluster_31

Target	Alias	Description	ECC score	Gene Family Method
AAK99601	spr0797, pykF	Pyruvate kinase I; fructose-stimulated [Ensembl]....	0.05	OrthoFinder
AAL20302	STM1378, pykF	pyruvate kinase I [Ensembl]. Pyruvate kinase [Interproscan].	0.23	OrthoFinder
AAL20804	STM1888, pykA	pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].	0.26	OrthoFinder
AEA93466	pyk, OG1RF_10779	pyruvate kinase [Ensembl]. Pyruvate kinase,...	0.07	OrthoFinder
AGT23623	N559_1890	pyruvate kinase [Ensembl]. barrel domain, alpha/beta...	0.11	OrthoFinder
AGT23869	N559_2155	pyruvate kinase [Ensembl]. barrel domain, alpha/beta...	0.04	OrthoFinder
AKI49567	pyk, L2625_01676	pyruvate kinase [Ensembl]. PEP-utilising enzyme,...	0.03	OrthoFinder
AKP15076	pykA, WX61_01018	Pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].	0.03	OrthoFinder
CCG26415	No alias	Pyruvate kinase [Ensembl]. Pyruvate kinase [Interproscan].	0.05	OrthoFinder
CPD26981	pykA, ERS093114_02430	Pyruvate kinase [Ensembl]. Pyruvate kinase,...	0.1	OrthoFinder
CRP56454	pykA	Pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].	0.03	OrthoFinder
KNA49521	VCV51_030321	pyruvate kinase [Ensembl]. Pyruvate kinase [Interproscan].	0.18	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004743	pyruvate kinase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0005975	carbohydrate metabolic process	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006090	pyruvate metabolic process	None	Extended
BP	GO:0006091	generation of precursor metabolites and energy	None	Extended
BP	GO:0006096	glycolytic process	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006165	nucleoside diphosphate phosphorylation	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006757	ATP generation from ADP	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009132	nucleoside diphosphate metabolic process	None	Extended
BP	GO:0009135	purine nucleoside diphosphate metabolic process	None	Extended
BP	GO:0009150	purine ribonucleotide metabolic process	None	Extended
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	None	Extended
BP	GO:0009185	ribonucleoside diphosphate metabolic process	None	Extended
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016052	carbohydrate catabolic process	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030955	potassium ion binding	IEA	Interproscan
MF	GO:0031420	alkali metal ion binding	None	Extended
BP	GO:0032787	monocarboxylic acid metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046031	ADP metabolic process	None	Extended
BP	GO:0046034	ATP metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
BP	GO:0046939	nucleotide phosphorylation	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003872	6-phosphofructokinase activity	IEP	Enrichment
MF	GO:0004340	glucokinase activity	IEP	Enrichment
MF	GO:0004347	glucose-6-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Enrichment
MF	GO:0004396	hexokinase activity	IEP	Enrichment
MF	GO:0004592	pantoate-beta-alanine ligase activity	IEP	Enrichment
MF	GO:0004618	phosphoglycerate kinase activity	IEP	Enrichment
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Enrichment
MF	GO:0004807	triose-phosphate isomerase activity	IEP	Enrichment
MF	GO:0005536	glucose binding	IEP	Enrichment
BP	GO:0005996	monosaccharide metabolic process	IEP	Enrichment
BP	GO:0006006	glucose metabolic process	IEP	Enrichment
BP	GO:0006007	glucose catabolic process	IEP	Enrichment
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
MF	GO:0008443	phosphofructokinase activity	IEP	Enrichment
BP	GO:0008643	carbohydrate transport	IEP	Enrichment
MF	GO:0008942	nitrite reductase [NAD(P)H] activity	IEP	Enrichment
BP	GO:0009061	anaerobic respiration	IEP	Enrichment
BP	GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system	IEP	Enrichment
BP	GO:0015939	pantothenate metabolic process	IEP	Enrichment
BP	GO:0015940	pantothenate biosynthetic process	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	IEP	Enrichment
MF	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor	IEP	Enrichment
MF	GO:0016774	phosphotransferase activity, carboxyl group as acceptor	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Enrichment
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Enrichment
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Enrichment
MF	GO:0019200	carbohydrate kinase activity	IEP	Enrichment
BP	GO:0019318	hexose metabolic process	IEP	Enrichment
BP	GO:0019320	hexose catabolic process	IEP	Enrichment
BP	GO:0019645	anaerobic electron transport chain	IEP	Enrichment
MF	GO:0020037	heme binding	IEP	Enrichment
BP	GO:0022900	electron transport chain	IEP	Enrichment
BP	GO:0022904	respiratory electron transport chain	IEP	Enrichment
MF	GO:0042279	nitrite reductase (cytochrome, ammonia-forming) activity	IEP	Enrichment
MF	GO:0043546	molybdopterin cofactor binding	IEP	Enrichment
BP	GO:0046168	glycerol-3-phosphate catabolic process	IEP	Enrichment
BP	GO:0046365	monosaccharide catabolic process	IEP	Enrichment
MF	GO:0046857	oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0046906	tetrapyrrole binding	IEP	Enrichment
MF	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Enrichment
BP	GO:0052646	alditol phosphate metabolic process	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
MF	GO:0098809	nitrite reductase activity	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR015793	Pyrv_Knase_brl	6	344
IPR015795	Pyrv_Knase_C	363	477

External Links

UniProtKB	P21599

AAC74924 (pykA, b1854)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation