GO:0009401: phosphoenolpyruvate-dependent sugar phosphotransferase system (Biological process)

"The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC." [http://www.ucs.mun.ca/~n55lrb/general_pts.html]


There are 2540 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_13 Clostridioides difficile 15.09 % 1e-06 0.000131
Cluster_26 Enterococcus faecalis 12.2 % 0.006366 0.048378
Cluster_8 Enterococcus faecalis 11.94 % 0.000629 0.027671
Cluster_1 Enterococcus faecalis 8.89 % 4.3e-05 0.005446
Cluster_14 Enterococcus faecalis 19.57 % 5e-06 0.000498
Cluster_16 Enterococcus faecalis 10.99 % 0.000254 0.035813
Cluster_10 Escherichia coli 5.91 % 0.0 9e-06
Cluster_14 Escherichia coli 7.14 % 0.000129 0.01185
Cluster_19 Klebsiella pneumoniae 6.98 % 0.000582 0.004513
Cluster_30 Klebsiella pneumoniae 5.33 % 0.000186 0.004048
Cluster_8 Listeria monocytogenes 13.76 % 0.0 1.7e-05
Cluster_23 Listeria monocytogenes 15.69 % 8.4e-05 0.009003
Cluster_22 Listeria monocytogenes 21.15 % 0.0 1.9e-05
Cluster_17 Listeria monocytogenes 24.0 % 0.0 0.0
Cluster_51 Pseudomonas aeruginosa 2.38 % 0.001603 0.008259
Cluster_67 Salmonella enterica 66.67 % 0.000338 0.011829
Cluster_35 Salmonella enterica 4.93 % 0.000709 0.009687
Cluster_11 Staphylococcus aureus 7.21 % 6e-06 0.000726
Cluster_6 Streptococcus pneumoniae 11.93 % 0.0 0.0
Cluster_2 Streptococcus pyogenes 6.78 % 0.000103 0.002834
Sequences (2540) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms