AAC75083 (hisB, b2022)

Aliases : hisB, b2022

Description : histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase [Ensembl]. Polynucleotide kinase 3 phosphatase, Imidazoleglycerol-phosphate dehydratase [Interproscan].

Gene families : OG_02_0000943 (OrthoFinder) Phylogenetic Tree(s): OG0000943_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC75083
Cluster	HCCA: Cluster_32

Target	Alias	Description	ECC score	Gene Family Method
AAL20978	STM2074, hisB	imidazole glycerol-phosphate dehydratase [Ensembl]....	0.14	OrthoFinder
AGT23515	N559_1779	histidinol-phosphatase/imidazoleglycerol-phosphate...	0.1	OrthoFinder
AHY40772	CJ8421_08000	imidazole glycerol-phosphate dehydratase/histidinol...	0.04	OrthoFinder
AKI48515	hisB, L2625_00579	imidazoleglycerol-phosphate dehydratase [Ensembl]....	0.06	OrthoFinder
CCL17753	hisB, BN171_1750014	Imidazoleglycerol-phosphate dehydratase [Ensembl]....	0.11	OrthoFinder
CCP44365	hisB, Rv1601	Probable imidazole glycerol-phosphate dehydratase HisB...	0.02	OrthoFinder
CPC68085	hisB, ERS093114_01042	imidazoleglycerol-phosphate dehydratase [Ensembl]....	0.21	OrthoFinder
EDJ91521	CGSHi22421_07117	imidazole glycerol-phosphate dehydratase/histidinol...	0.15	OrthoFinder

Type	GO Term	Name	Evidence	Source
BP	GO:0000105	histidine biosynthetic process	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004424	imidazoleglycerol-phosphate dehydratase activity	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006547	histidine metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016829	lyase activity	None	Extended
MF	GO:0016835	carbon-oxygen lyase activity	None	Extended
MF	GO:0016836	hydro-lyase activity	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEP	Enrichment
MF	GO:0003879	ATP phosphoribosyltransferase activity	IEP	Enrichment
MF	GO:0004399	histidinol dehydrogenase activity	IEP	Enrichment
MF	GO:0004635	phosphoribosyl-AMP cyclohydrolase activity	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
MF	GO:0005507	copper ion binding	IEP	Enrichment
BP	GO:0006553	lysine metabolic process	IEP	Enrichment
MF	GO:0008839	4-hydroxy-tetrahydrodipicolinate reductase	IEP	Enrichment
BP	GO:0009066	aspartate family amino acid metabolic process	IEP	Enrichment
BP	GO:0009067	aspartate family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009085	lysine biosynthetic process	IEP	Enrichment
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Enrichment
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016763	pentosyltransferase activity	IEP	Enrichment
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEP	Enrichment
MF	GO:0019238	cyclohydrolase activity	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043169	cation binding	IEP	Enrichment
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Enrichment
BP	GO:0046451	diaminopimelate metabolic process	IEP	Enrichment
MF	GO:0046872	metal ion binding	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013954	PNK3P	8	134
IPR000807	ImidazoleglycerolP_deHydtase	196	337

External Links

UniProtKB	P06987

AAC75083 (hisB, b2022)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation