Coexpression cluster: Cluster_5 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0034220 ion transmembrane transport 23.53% (12/51) 5.44 0.0 0.0
GO:1902600 proton transmembrane transport 21.57% (11/51) 5.66 0.0 0.0
GO:0098655 cation transmembrane transport 21.57% (11/51) 5.53 0.0 0.0
GO:0098662 inorganic cation transmembrane transport 21.57% (11/51) 5.53 0.0 0.0
GO:0098660 inorganic ion transmembrane transport 21.57% (11/51) 5.53 0.0 0.0
GO:0046034 ATP metabolic process 17.65% (9/51) 5.25 0.0 0.0
GO:0006811 ion transport 23.53% (12/51) 3.89 0.0 0.0
GO:0006812 cation transport 21.57% (11/51) 4.08 0.0 0.0
GO:0006754 ATP biosynthetic process 9.8% (5/51) 5.66 0.0 0.0
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 9.8% (5/51) 5.66 0.0 0.0
GO:0009144 purine nucleoside triphosphate metabolic process 9.8% (5/51) 5.66 0.0 0.0
GO:0009145 purine nucleoside triphosphate biosynthetic process 9.8% (5/51) 5.66 0.0 0.0
GO:0009142 nucleoside triphosphate biosynthetic process 9.8% (5/51) 5.66 0.0 0.0
GO:0015986 ATP synthesis coupled proton transport 9.8% (5/51) 5.66 0.0 0.0
GO:0009205 purine ribonucleoside triphosphate metabolic process 9.8% (5/51) 5.66 0.0 0.0
GO:0009199 ribonucleoside triphosphate metabolic process 9.8% (5/51) 5.66 0.0 0.0
GO:0009201 ribonucleoside triphosphate biosynthetic process 9.8% (5/51) 5.66 0.0 0.0
GO:0015985 energy coupled proton transport, down electrochemical gradient 9.8% (5/51) 5.66 0.0 0.0
GO:0015078 proton transmembrane transporter activity 11.76% (6/51) 5.25 0.0 0.0
GO:0055085 transmembrane transport 27.45% (14/51) 2.6 0.0 0.0
GO:0022890 inorganic cation transmembrane transporter activity 11.76% (6/51) 4.66 0.0 0.0
GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain 7.84% (4/51) 5.66 0.0 1e-06
GO:0009152 purine ribonucleotide biosynthetic process 9.8% (5/51) 4.98 0.0 1e-06
GO:0046390 ribose phosphate biosynthetic process 9.8% (5/51) 4.98 0.0 1e-06
GO:0009260 ribonucleotide biosynthetic process 9.8% (5/51) 4.98 0.0 1e-06
GO:0009141 nucleoside triphosphate metabolic process 9.8% (5/51) 4.98 0.0 1e-06
GO:0019693 ribose phosphate metabolic process 11.76% (6/51) 4.34 0.0 1e-06
GO:0009259 ribonucleotide metabolic process 11.76% (6/51) 4.34 0.0 1e-06
GO:0009150 purine ribonucleotide metabolic process 11.76% (6/51) 4.34 0.0 1e-06
GO:0006163 purine nucleotide metabolic process 11.76% (6/51) 4.16 0.0 3e-06
GO:0015318 inorganic molecular entity transmembrane transporter activity 11.76% (6/51) 4.16 0.0 3e-06
GO:0006164 purine nucleotide biosynthetic process 9.8% (5/51) 4.66 1e-06 3e-06
GO:1901137 carbohydrate derivative biosynthetic process 9.8% (5/51) 4.66 1e-06 3e-06
GO:0098796 membrane protein complex 9.8% (5/51) 4.66 1e-06 3e-06
GO:0072521 purine-containing compound metabolic process 11.76% (6/51) 4.08 1e-06 3e-06
GO:0072522 purine-containing compound biosynthetic process 9.8% (5/51) 4.52 1e-06 5e-06
GO:0008324 cation transmembrane transporter activity 11.76% (6/51) 3.85 2e-06 9e-06
GO:0009117 nucleotide metabolic process 11.76% (6/51) 3.66 5e-06 2e-05
GO:1901293 nucleoside phosphate biosynthetic process 9.8% (5/51) 4.08 6e-06 2.7e-05
GO:0009165 nucleotide biosynthetic process 9.8% (5/51) 4.08 6e-06 2.7e-05
GO:0006753 nucleoside phosphate metabolic process 11.76% (6/51) 3.49 1e-05 3.8e-05
GO:0015075 ion transmembrane transporter activity 11.76% (6/51) 3.49 1e-05 3.8e-05
GO:0032991 protein-containing complex 9.8% (5/51) 3.59 4e-05 0.000154
GO:0090407 organophosphate biosynthetic process 9.8% (5/51) 3.52 5.1e-05 0.000192
GO:0051234 establishment of localization 27.45% (14/51) 1.67 6.2e-05 0.00022
GO:0051179 localization 27.45% (14/51) 1.67 6.2e-05 0.00022
GO:0006810 transport 27.45% (14/51) 1.67 6.2e-05 0.00022
GO:0019637 organophosphate metabolic process 11.76% (6/51) 3.0 7.5e-05 0.000263
GO:0055086 nucleobase-containing small molecule metabolic process 11.76% (6/51) 2.82 0.000155 0.000527
GO:0006796 phosphate-containing compound metabolic process 11.76% (6/51) 2.72 0.000227 0.000758
GO:0006793 phosphorus metabolic process 11.76% (6/51) 2.69 0.000256 0.000839
GO:0034654 nucleobase-containing compound biosynthetic process 9.8% (5/51) 2.98 0.000333 0.00107
GO:1901135 carbohydrate derivative metabolic process 11.76% (6/51) 2.6 0.000362 0.0011
GO:0022857 transmembrane transporter activity 19.61% (10/51) 1.82 0.00036 0.001114
GO:0005215 transporter activity 19.61% (10/51) 1.82 0.00036 0.001114
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 3.92% (2/51) 5.66 0.000384 0.001124
GO:0015252 proton channel activity 3.92% (2/51) 5.66 0.000384 0.001124
GO:0019438 aromatic compound biosynthetic process 9.8% (5/51) 2.62 0.001084 0.003122
GO:0005261 cation channel activity 3.92% (2/51) 5.08 0.001136 0.003216
GO:0018130 heterocycle biosynthetic process 9.8% (5/51) 2.52 0.001502 0.004182
GO:1901362 organic cyclic compound biosynthetic process 9.8% (5/51) 2.43 0.002029 0.005555
GO:0005216 ion channel activity 3.92% (2/51) 4.34 0.003692 0.009943
GO:1901566 organonitrogen compound biosynthetic process 11.76% (6/51) 1.96 0.003839 0.010176
GO:0042626 ATPase-coupled transmembrane transporter activity 5.88% (3/51) 3.0 0.005648 0.014738
GO:0044271 cellular nitrogen compound biosynthetic process 11.76% (6/51) 1.84 0.005882 0.015112
GO:0015399 primary active transmembrane transporter activity 5.88% (3/51) 2.92 0.006553 0.016581
GO:0009987 cellular process 31.37% (16/51) 0.86 0.009221 0.022984
GO:0022803 passive transmembrane transporter activity 3.92% (2/51) 3.66 0.00995 0.024082
GO:0015267 channel activity 3.92% (2/51) 3.66 0.00995 0.024082
GO:0044281 small molecule metabolic process 11.76% (6/51) 1.49 0.018207 0.043436
GO:0004618 phosphoglycerate kinase activity 1.96% (1/51) 5.66 0.019775 0.043453
GO:0033179 proton-transporting V-type ATPase, V0 domain 1.96% (1/51) 5.66 0.019775 0.043453
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) 1.96% (1/51) 5.66 0.019775 0.043453
GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain 1.96% (1/51) 5.66 0.019775 0.043453
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) 1.96% (1/51) 5.66 0.019775 0.043453
GO:0004807 triose-phosphate isomerase activity 1.96% (1/51) 5.66 0.019775 0.043453
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Clostridioides difficile HCCA Cluster_20 0.083 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_31 0.061 OrthoFinder Compare
Escherichia coli HCCA Cluster_1 0.04 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_13 0.031 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_12 0.044 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_7 0.088 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_1 0.04 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_22 0.032 OrthoFinder Compare
Salmonella enterica HCCA Cluster_6 0.034 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_12 0.043 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_3 0.027 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_14 0.029 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_2 0.053 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_4 0.045 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_16 0.031 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_9 0.058 OrthoFinder Compare
Sequences (51) (download table)

InterPro Domains

GO Terms

Family Terms